A5030932376- NF-κB Signaling Pathways
- Neonatal Respiratory Health Research
- Agricultural pest management studies
- Mass Spectrometry Techniques and Applications
- Epigenetics and DNA Methylation
- Immune Response and Inflammation
- Melanoma and MAPK Pathways
- Agricultural Science and Fertilization
- Genetic and Environmental Crop Studies
- RNA modifications and cancer
- Protein Kinase Regulation and GTPase Signaling
- Receptor Mechanisms and Signaling
- MicroRNA in disease regulation
- Infant Nutrition and Health
- RNA and protein synthesis mechanisms
- DNA Repair Mechanisms
- Analytical Chemistry and Sensors
- Quantum Information and Cryptography
- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- Arsenic contamination and mitigation
- Cold Atom Physics and Bose-Einstein Condensates
- Advanced Proteomics Techniques and Applications
- Silicon and Solar Cell Technologies
- Atherosclerosis and Cardiovascular Diseases
Massachusetts General Hospital
2024
Harvard University
2024
University of Massachusetts Boston
2021-2023
University of New Mexico
2023
Bangladesh Agricultural Research Institute
2020
Institute of Science and Technology
2015
Sadjad University of Technology
2015
University of Dhaka
2014
Temple University
2012-2013
Thomas Jefferson University
2011-2012
The non-carcinogenic and carcinogenic risk of arsenic lead to adults children via daily dietary intake food composites in Bangladesh was estimated. target hazard quotients (THQs), index (HI) (TR) were calculated evaluate the health from lead. Most individual contain a considerable amount highest mean concentrations found cereals (0.254 mg kg⁻¹ fw) vegetables (0.250 fw), (0.714 fish (0.326 fw). results showed THQs for both which exceeded safe limit (> 1) indicating that are main items...
Background —Monocyte-endothelium adhesion is a crucial early event in atherogenesis. Several reports indicate that α-tocopherol (AT) potent antioxidant plasma and LDL also has intracellular effects are antiatherogenic. Recently, it been shown AT supplementation results decreased monocyte–endothelial cell adhesion. However, there paucity of data on the mechanisms by which inhibits monocytes. We studied effect enrichment human monocytic line, U937, to umbilical vein endothelial cells (HUVECs)....
An assay method for GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha 1-6fucosyltransferase (alpha 1-6FucT; EC 2.4.1.68) activity has been developed, involving a fluorescent pyridylaminated substrate. A glycopeptide derived from bovine gamma-globulin was coupled with 4-(2-pyridylamino)butylamine (PABA) through the peptide bond, and following substrate obtained. [equation: see text] The guanosine diphospho-fucopyranoside (GDP-Fuc) were incubated crude enzyme extract 2 h, then enzymatic product...
Surfactant protein A (SP-A) is important for immune defense within the alveolus.Cyclic AMP (cAMP) stimulation of SP-A expression in lung type II cells O 2 dependent and mediated by increased phosphorylation binding thyroid transcription factor 1 (TTF-1) to an upstream response element (TTF-1-binding [TBE]).Interleukin-1 (IL-1) NF-B (p65/p50) activation TBE.In this study, we found that also was permissive IL-1 induction cAMP cell nuclear TBE.Using chromatin immunoprecipitation, observed when...
Surfactant protein-A (SP-A) gene expression in human fetal lung type II cells is stimulated by cAMP and IL-1 inhibited glucocorticoids. cAMP/IL-1 stimulation of SP-A mediated increased binding thyroid transcription factor-1 nuclear factor (NF)-kappaB to the TTF-1-binding element (TBE) promoter. This associated with decreased histone deacetylases (HDACs), recruitment coactivators, enhanced acetylation H3 (K9,14) at TBE. In present study, endogenous glucocorticoid receptor (GR) was found...
High grade serous ovarian carcinoma (HGSOC) is the most common and aggressive malignancy. Accumulating evidence indicates that HGSOC may originate from human fallopian tube epithelial cells (FTECs), although exact pathogen(s) and/or molecular mechanism underlying malignant transformation of FTECs unclear. Here we show papillomavirus (HPV), which could reach via retrograde menstruation or sperm-carrying, interacts with yes-associated protein 1 (YAP1) to drive FTECs. HPV prevents natural...
Abstract The human surfactant protein-A2 (hSP-A2) gene is developmentally regulated, expressed in type II pneumonocytes, and induced by cAMP. cAMP induction of hSP-A2 expression O2 dependent mediated increased phosphorylation, DNA binding, transcriptional activation thyroid transcription factor-1 (TTF-1). TTF-1-binding element (TBE) at −175 bp contains a reverse-oriented nuclear factor-κB (NF-κB) binding site. IL-1 SP-A lung cells had additive stimulatory effects with Nuclear extracts from...
The double stranded RNA binding protein Adad1 (adenosine deaminase domain containing 1) is a member of the adenosine acting on RNAs (Adar) family with germ cell-specific expression. In mice, necessary for sperm differentiation, however its function outside mammals has not been investigated. Here, through an N-ethyl-N-nitrosourea (ENU) based forward genetic screen, we identified adad1 mutant zebrafish line that develops as sterile males. Further histological examination revealed complete lack...
Oxidative stress has been implicated in the pathogenesis of various cardiovascular diseases, including ischemic heart disease and failure. The peroxisome proliferator-activated receptor gamma (PPARγ) agonist improves insulin sensitivity limits tissue inflammation cellular apoptosis, but there are few data on relationship between PPARγ agonist, rosiglitazone (RSG), thioredoxin (TRx) system oxidatively stressed cardiomyocytes (CMCs). Here we provide evidence that RSG protects rat CMCs from...
Induction of surfactant protein-A (SP-A) gene expression in fetal lung type II cells by cAMP and IL-1 is mediated increased binding thyroid transcription factor-1 (TTF-1) NF-B proteins p50 p65 to the TTF-1-binding element (TBE) at -183 bp. In cell transfections, dexamethasone (Dex) markedly inhibits cAMP-induced rabbit SP-A:human growth hormone (hGH) fusion genes containing as little 300 bp SP-A 5'-flanking sequence. Dex inhibition blocked RU-486, suggesting a role glucocorticoid receptor...
The eukaryotic structural maintenance of chromosomes (SMC) proteins are involved in key processes chromosome structure and dynamics. SMC1β was identified as a component the meiotic cohesin complex vertebrates, which aids keeping sister chromatids together prior to segregation meiosis II is association homologous I. role has primarily been studied mice, where mutant male female mice infertile due germ cell arrest at pachytene metaphase stages, respectively. Here, we investigate function...
The experiment was conducted to know the abundance of major insect pests on 15 mungbean varieties viz., BARI Mung-1, Mung-2, Mung-3, Mung-4, Mung-5, Mung-6, BINA Moog-4, Moog-5, Moog-6, Moog-7, Moog-8, BU Mug-1, Mug-2, Mug-4 and Patuakhali local Mung role weather parameters population mobility insects at farmer’s field sadar upazila district, Bangladesh during late Robi season 2016. Variety Mung-4 had lowest number leaf folder while variety Mung-6 highest indicating higher susceptibility...
Thin film solar cells have gained a lot of attention due to the reduced material cost. However, decreasing thickness reduces overall current cell can generate. As result, use nanoparticles improve performance thin is topic increased research and interest [1, 2]. Semiconductor allow absorption photons higher energy emission lower energy. In this work, effect luminescent indium nitride (InN-NPs) spin coated on top a-Si:H studied. The generation InN-NPs was carried out using nanosecond pulsed...
ABSTRACT The eukaryotic structural maintenance of chromosomes (SMC) proteins are involved in key processes chromosome structure and dynamics. SMC1β was identified as a component the meiotic cohesion complex vertebrates, which aids keeping sister chromatids together prior to segregation meiosis II is association homologous I. role has primarily been studied mice, where mutant male female mice infertile due germ cell arrest at pachytene metaphase stages, respectively. Here, we investigate...
Mungbean is one of the important pulse crops in Bangladesh. More than 12 species insect pests infest mungbean, among them flea beetle cause significant yield loss due to attack from seedling vegetative stages. The experiment was conducted find out tolerant and susceptible varieties mungbean against at farmer’s field Patuakhali, Bangladesh January April 2016. Results revealed that BARI Mung-4 had lowest abundance while BINA Moog-7 Mung-6 highest abundance. Among tested all varieties,...