A5016094734- Orthopaedic implants and arthroplasty
- Radiomics and Machine Learning in Medical Imaging
- Hip disorders and treatments
- Orthopedic Infections and Treatments
- Bone Tissue Engineering Materials
- Advanced X-ray and CT Imaging
- Cardiac Valve Diseases and Treatments
- Dental Implant Techniques and Outcomes
- Advanced materials and composites
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Anatomy and Medical Technology
- Metal and Thin Film Mechanics
- Ultrasound and Hyperthermia Applications
- Advanced Neuroimaging Techniques and Applications
- Total Knee Arthroplasty Outcomes
- Ultrasound Imaging and Elastography
- Lower Extremity Biomechanics and Pathologies
- Surface Treatment and Coatings
- Musculoskeletal synovial abnormalities and treatments
- Bacterial biofilms and quorum sensing
- Acute Ischemic Stroke Management
The University of Texas Southwestern Medical Center
2016-2020
Southwestern Medical Center
2017-2020
Advanced Imaging Research (United States)
2017
The University of Texas at Dallas
2015
Abstract Treatment of prosthetic joint infection (PJI) usually requires surgical replacement the infected and weeks antibiotic therapy, due to formation biofilm. We introduce a non-invasive method for thermal destruction biofilm on metallic implants using high-frequency (>100 kHz) alternating magnetic fields (AMF). In vitro investigations demonstrate >5-log reduction in bacterial counts after 5 minutes AMF exposure. Confocal scanning electron microscopy confirm removal matrix...
Purpose: Localised hyperthermia in rodent studies is challenging due to the small target size. This study describes development and characterisation of an MRI-compatible high-intensity focused ultrasound (HIFU) system perform localised mild treatments models. Material methods: The platform consisted animal HIFU system, transducers with sector-vortex lenses, a custom-made receive coil, means maintain systemic temperatures rodents. was integrated into 3T MR imager. Control software developed...
The aim of this study was to compare the anatomical registration preoperative magnetic resonance imaging (MRI) and prostate whole-mount obtained with 3D-printed, patient-specific, MRI-derived molds (PSM) versus conventional sectioning (WMS).Based on an a priori power analysis, institutional review board-approved prospectively included 50 consecutive men who underwent 3 T multiparametric MRI followed by radical prostatectomy. Two blinded independent readers (R1 R2) outlined contours prostate,...
Treatment of prosthetic joint infections often involves multiple surgeries and prolonged antibiotic administration, resulting in a significant burden to patients the healthcare system. We are exploring non-invasive method eradicate biofilm on metal implants utilizing high-frequency alternating magnetic fields (AMF) which can achieve surface induction heating. Although proof-of-concept studies demonstrate ability AMF vitro, there is legitimate safety concern related potential for thermal...
Evaluate feasibility and reliability of 3DCT semi-automatic segmentation volumetrics CAM lesions in femoroacetabular impingement determine correlations with anthropometrics.A consecutive series 43 patients type FAI underwent 3DCT. 20 males 23 females (30 unilateral 13 bilateral symptomatic hips) were included. 56 femoral heads segmented by two readers. Radial images obtained for alpha angles. Pearson ICC used analysis.In (male: female = 1 : 1.15), mean ± SD age, height, BMI 36.6 11.47 years,...
Femoroacetabular impingement (FAI) and hip dysplasia are the most common causes of groin pain originating from joint. To date, there is controversy over cut-off values for evaluation abnormal femoral head-neck anatomy with significant overlap between normal hips. Our aim was to perform three-dimensional CT analysis head bump quantify pathologies (FAI dysplasia)
Susceptibility artifacts caused by stainless steel orthodontic appliances (braces) pose significant challenges in clinical brain MRI examinations. We introduced field correction device (FCD) utilizing permanent magnets to cancel the induced B0 inhomogeneity and mitigate geometric distortions MRI. evaluated a prototype FCD using 3D-printed head phantom this proof of concept study. The was compartmented into anterior frontal lobe, temporal fronto-parieto-occipital basal ganglia thalami, stem,...
44 Background: A critical requirement for imaging-pathology correlation is adequate image registration. Since the prostate deformable, sectioning gland in a plane similar to imaging challenging. To improve vivo and ex histology registration, 3D-printed, patient-specific, MRI-derived molds (PSMs) whole-mount processing have been proposed. This study compared anatomical registration of preoperative MRI whole-mounts obtained with PSMs versus conventional (WMS). Methods: Based on an priori power...