A5036828645- Additive Manufacturing and 3D Printing Technologies
- Welding Techniques and Residual Stresses
- Liver Disease Diagnosis and Treatment
- Spondyloarthritis Studies and Treatments
- Chemokine receptors and signaling
- Psoriasis: Treatment and Pathogenesis
- Pluripotent Stem Cells Research
- Diet, Metabolism, and Disease
- Additive Manufacturing Materials and Processes
- Glioma Diagnosis and Treatment
- Nerve injury and regeneration
- Cardiovascular Disease and Adiposity
- Nanoplatforms for cancer theranostics
- Peripheral Artery Disease Management
- Rheumatoid Arthritis Research and Therapies
- Angiogenesis and VEGF in Cancer
- Coronary Interventions and Diagnostics
- HER2/EGFR in Cancer Research
- Neurological disorders and treatments
- Synthesis and biological activity
- Quinazolinone synthesis and applications
- Cytokine Signaling Pathways and Interactions
- Lung Cancer Treatments and Mutations
- Nanoparticle-Based Drug Delivery
Agency for Science, Technology and Research
2019-2024
Institute of Materials Research and Engineering
2024
Australian Research Council
2022
The University of Queensland
2022
ARC Centre of Excellence in Advanced Molecular Imaging
2022
Singapore Bioimaging Consortium
2019-2020
NIHR Leeds Musculoskeletal Biomedical Research Unit
2012
University of Leeds
2012
Purpose . Peripheral artery disease (PAD) causes narrowing of arteries in the limbs, leading to tissue ischemia, gangrene, and eventually limb amputation. The presence diabetes greatly exacerbates course PAD, accounting for majority lower amputations. Therapeutic strategies focussing on macrovascular repair are less effective diabetic patients where smaller vessels affected, proangiogenic therapies offer a viable adjunct improve vascularisation these at risk individuals. purpose current...
Abstract Background Significant developments in stem cell therapy for Parkinson’s disease (PD) have already been achieved; however, methods reliable assessment of dopamine neuron maturation vivo are lacking. Establishing the efficacy new cellular therapies using non-invasive methodologies will be critical future regulatory approval and application. The current study examines utility neuroimaging to characterise maturation, innervation functional release transplanted human embryonic...
Purpose . Liver fibrosis is the hallmark of chronic nonalcoholic steatohepatitis (NASH) and characterised by excessive deposition extracellular matrix proteins. Early detection accurate staging liver critically important for patient management. One earliest pathological markers in NASH activation hepatic stellate cells (HSCs) which may be exploited as a marker fibrogenesis. Activated HSCs secreting factors such integrin α v β 3 propagate fibrosis. The purpose current study was to assess...
Metal products fabricated by additive manufacturing (AM), face challenges in mechanical property evaluation due to the complex thermal history of process. This study used Ti-6Al-4V alloy, widely AM examine applicability Gibson-Ashby model for samples with porosities lower than 5%. Observations from electron backscatter diffraction (EBSD) and X-ray (XRD) demonstrated that model's accuracy is limited changes topology pores phase proportions different processing parameters. However, adaptive...
Specific mutations significantly affect response to epidermal growth factor tyrosine kinase inhibitor (EGFR‐TKI) treatment in lung cancer patients. Identifying patients with these remains a major clinical challenge. EGFR T790M mutation, which conveys resistance the present study, [ 18 F]FEWZ was assessed vitro determine efficacy relative starting compound and vivo measure biodistribution specificity of binding wild‐type, L858R bearing tumours. is first evidence radiolabeled third generation...