A5021889989- Bariatric Surgery and Outcomes
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Body Contouring and Surgery
- Gastric Cancer Management and Outcomes
- Dental Erosion and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Diet and metabolism studies
- Intestinal and Peritoneal Adhesions
- Metabolism and Genetic Disorders
- Opioid Use Disorder Treatment
- Hernia repair and management
- Enhanced Recovery After Surgery
- Dental materials and restorations
- Abdominal Surgery and Complications
- Appendicitis Diagnosis and Management
- Hemoglobin structure and function
- Protein Structure and Dynamics
- Dental Anxiety and Anesthesia Techniques
- Enzyme Structure and Function
- Gastrointestinal disorders and treatments
- Biochemical and Molecular Research
- Pelvic and Acetabular Injuries
- Dysphagia Assessment and Management
- Minimally Invasive Surgical Techniques
Geisinger Health System
2021-2025
Geisinger Medical Center
2013-2024
The University of Texas Medical Branch at Galveston
2020-2024
Gold Coast Hospital
2011-2024
Saint Xavier University
2021
Norfolk Record Office
2020
Gold Coast Health
2019
Queensland Health
2019
RELX Group (United States)
2018
RELX Group (Netherlands)
2018
We tested the hypothesis that tumor necrosis factor-alpha (TNF) induces a peroxynitrite (ONOO-)-mediated depletion of glutathione via protein kinase C (PKC)-dependent mechanism in pulmonary artery endothelial monolayers (PAEM). PAEM were incubated with TNF (1,000 U/ml) for 6 and 18 h. The assayed ONOO(-)-dependent changes concentration luminol, free [Gfree; i.e., reduced oxidized (GSSG)] GSSG. treatment decreased luminol Gfree, increased GSSG GSSG/Gfree, compared control media. TNF-induced...
Dental erosion involves dissolution of the hydroxyapatite fraction enamel and dentine, so agents that reduce rate could find application in food products aimed at reducing erosion. This study was performed to test some common ingredients additives for their effect on a citric acid solution representative soft drinks. Pyrophosphate, tripolyphosphate linear chain polyphosphate (average 25 phosphate units) significantly reduced by 35, 46 64%, respectively. Xanthan gum carboxymethylcellulose 29...
Current treatment outcome of patients with glioblastoma (GBM) remains poor. Following standard therapy, recurrence is universal limited survival. Tumors from 173 GBM are analysed for somatic mutations to generate a personalized peptide vaccine targeting tumor-specific neoantigens. All were treated within the scope an individual healing attempt. Among all vaccinated patients, including 70 prior progression (primary) and 103 after (recurrent), median overall survival first diagnosis 31.9...
The aim of this study was to investigate enamel dissolution in citric acid solutions as a function solution calcium and phosphate concentrations degree saturation with respect hydroxyapatite (DSHA). primary relevance the is development soft drinks reduced erosive potential. Nanoindentation used changes hardness polished human surfaces after 120 s 300 exposure pH 3.30 range concentrations. All were undersaturated hydroxyapatite, 0.000 < or = DSHA 0.295. A complex dependence softening on...
Because unsubstantiated beliefs link hysterectomy and cholecystectomy with bowel function, this study examined all the women who had these operations in a defined population (79 37 respectively, out of 1058) respect to habits, irritable syndrome symptoms, whole gut transit time calculated from records three defecations. Compared unoperated controls, after were more likely consider themselves constipated; they also strained admitted often bloating feelings incomplete evacuation. Their stools...
Abstract Background Emergency appendicectomy is the most common emergency surgical procedure performed in Australia. Despite this frequency, there a relative paucity of contemporary, broad‐based, local data that examine how appendicectomies are currently and what outcomes from these operations. Methods A multicentre, prospective, observational study was performed. Patients were recruited by investigators for period 2 months with 30‐day follow‐up. eligible inclusion if they underwent an...
The aim of the present in vitro study was to investigate toothbrush abrasion surface softened enamel using tapping mode atomic force microscopy (TM-AFM) and AFM nanoindentation. TM-AFM investigations showed that typical prismatic pattern as observed after demineralisation retained toothbrushing. exposure artificial saliva resulted deposition a 'sausage-shape' material with random orientation. Brushing these samples did not lead complete removal this deposited material. Enamel mineral loss...
1. The formation of the non-enzymic adduct NAD+ and sulphite was investigated. In agreement with others we conclude that dianion adds to NAD+. 2. ternary complexes either lactate dehydrogenase or malate u.v. spectrum NAD–sulphite same whether free enzyme-bound at pH6 pH8. This suggests adducts have a similar electronic structure. 3. effect pH on concentration bound both enzymes measured in new titration apparatus. Unlike (where stability change simply reflects HSO3−=SO32−+H+), showed...