A5085410047- Reproductive Biology and Fertility
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Sperm and Testicular Function
- Uterine Myomas and Treatments
- Gestational Trophoblastic Disease Studies
- Reproductive System and Pregnancy
- Reproductive Health and Technologies
- Ectopic Pregnancy Diagnosis and Management
- Maternal and Neonatal Healthcare
- Ovarian cancer diagnosis and treatment
- Muscle and Compartmental Disorders
- Obstructive Sleep Apnea Research
- Sleep and related disorders
- Polyomavirus and related diseases
- COVID-19 Impact on Reproduction
- Maternal and fetal healthcare
- Tissue Engineering and Regenerative Medicine
- Minimally Invasive Surgical Techniques
- Ureteral procedures and complications
- Renal Diseases and Glomerulopathies
- Pregnancy and preeclampsia studies
- Appendicitis Diagnosis and Management
- Neonatal and Maternal Infections
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
National Defense Medical Center
2009-2023
Tri-Service General Hospital
2008-2023
Chung Shan Medical University Hospital
2022-2023
Chung Shan Medical University
2023
Taipei City Hospital
2022
Taipei Municipal YangMing Hospital
2022
Cornell University
2020-2021
Weill Cornell Medicine
2020
Non-apnea sleep disorder (NASD) increases the risk of hypertension, type 2 diabetes mellitus, chronic kidney disease, cardiovascular and stroke. However, time interval NASD to female infertility has not been thoroughly understood. Our study aimed determine whether subsequent infertility.This utilized outpatient inpatient data from Longitudinal Health Insurance Database between 2000 2010 in Taiwan. We enrolled 50,154 females aged 20 45 years old diagnosed with as outpatients ≥2 times or...
Abstract We investigated the role of oxidative stress-responsive kinase-1 (OSR1) and STE20 (sterile 20)/SPS1-related proline/alanine-rich kinase (SPAK), upstream regulators Na + -K -2Cl − cotransporter (NKCC1)—essential for spermatogenesis—in mouse models male fertility. Global OSR1 +/− gene mutations, but not global SPAK −/− or Sertoli cell (SC)-specific knockout (SC-OSR1 ), cause subfertility with impaired sperm function are associated reduced abundance phosphorylated (p)-NKCC1 increased...
Does the presence of single-nucleotide polymorphisms (SNPs) in leukemia inhibitory factor (LIF) gene affect ovarian response infertile young women?This was a case-control study recruiting 1744 women between January 2014 to December 2015. The 1084 eligible patients were stratified into four groups using POSEIDON criteria. gonadotropin-releasing hormone receptor (GnRHR), follicle-stimulating (FSHR), anti-Müllerian (AMH), and LIF SNP genotypes compared among groups. distributions FSHR younger...
Ectopic pregnancy occurs in approximately 2% of all pregnancies, and over 95% ectopic pregnancies involve the oviduct. remains major cause first-trimester maternal death [1]. Tubal surgery is reported to be greatest risk factor for pregnancy. Other important factors include a previous pregnancy, utero diethylstilbestrol exposure, with an intrauterine device situ, documented tubal pathology, infertility, genital tract infection, history multiple sexual partners [2]. Transvaginal...
Abstract STUDY QUESTION Do the length of follicular phase estradiol exposure and total affect pregnancy live birth outcomes in natural frozen embryo transfer (FET) cycles? SUMMARY ANSWER An level >100 pg/ml for ≤4 days including LH surge day is associated with worse outcomes; however, not outcomes. WHAT IS KNOWN ALREADY that increases above 100 continues to increase indicative selection development a dominant follicle. In programmed FET cycles, limited duration <9 results...
Male pediatric survivors of cancers and bone marrow transplantation often require adjuvant chemoradiation therapy that may be gonadotoxic. The optimal methods to preserve fertility in these prepubertal males are still under investigation. This manuscript presents an vivo experiment which involved immature testicular tissues (ITT) from transgenic donor, wild-type recipient mice. Donors recipients were age-mismatched (from 20-week-old donors 3-week-old recipients, vice versa) the sites...
To report two cases of recurrent uterine sarcoma that developed ifosfamide-induced encephalopathy (IIE) with successful management. The patient in the first case grade 4 toxicity and had a partial response after fourth dose intravenous methylene blue was administered. Full recovery occurred days development IIE. second case, who 3 toxicity, completely recovered 32 hours thiamine. Careful evaluation patients gynecologic cancers vigilance during infusion chemotherapeutic regimens are important...
Most of the metastatic cervical lymphadenopathy results from upper aerodigestive tract [1]. Asymptomatic primary ovarian cancer in presence left supraclavicular lymph nodes is rare [2]. Whether to identify tumor or manage Stage IV represents a clinical dilemma. We report case adenocarcinoma fossa resulting occult cancer. A healthy 53-year-old menopausal woman, parity 2002, presented with growing lump as large 8 6 3 cm her fossa; she had mass for months, which on biopsy was diagnosed...
There was no national data on group B streptococcus (GBS) infections in Taiwan. Until 2012, when prenatal GBS screening introduced to obstetric practices as a health policy aimed at reducing neonatal infections. The purpose of this study examine the impact incidence maternal colonization and infection rate. Relatedly, clinical characteristics were investigated determine correlations between rate.This population-based nationwide used for 2012-2013 from National Health Insurance Research...
The use and application of robotic systems with a high-definition, three-dimensional vision system advanced EndoWrist technology have become widespread. We sought to share our clinical experience ureter identification preventive uterine artery ligation in hysterectomy. records patients undergoing hysterectomy between May 2014 December 2015, including patient preoperative characteristics, operative time, postoperative outcomes, were analyzed. evaluated the feasibility safety using early...
Injury of major retroperitoneal vascular structures is an infrequent complication laparoscopy. One the most severe complications that may occur during laparoscopic surgery trocar and Veress needle injuries to vessels. A case obese young female with ovarian teratoma, Rt suffered from postischemic compartment syndrome after laparoscopy though emergent revascularization was performed. Since this rare life-threatening conditions could easily be misdiagnosed mistreated, early diagnosis immediate...
Abstract Background: The optimal method for cryopreserving immature testicular tissue (ITT) remains unknown and there is no standardized protocol. Controlled slow freezing the mainstream of choice in human prepubertal male fertility preservation. Currently, outcomes ITT vitrification are conflicting, most data limited to vitro animal studies. Methods: A total 12 pairs donor recipient mice were included our experiments. donors transgenic mice, recipients wild-type mice. In group, was...