A5036781973- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Prenatal Screening and Diagnostics
- Reproductive Health and Technologies
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Renal and related cancers
- Pluripotent Stem Cells Research
- Epigenetics and DNA Methylation
- Uterine Myomas and Treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sexual function and dysfunction studies
- Family Dynamics and Relationships
- Ovarian cancer diagnosis and treatment
- Sexual Differentiation and Disorders
- Grief, Bereavement, and Mental Health
- Reproductive Health and Contraception
- COVID-19 Impact on Reproduction
- Maternal Mental Health During Pregnancy and Postpartum
- Genetic Syndromes and Imprinting
- Gut microbiota and health
- Infant Nutrition and Health
Chung Shan Medical University
2016-2025
Chung Shan Medical University Hospital
2016-2025
Taichung Hospital
1999-2023
National Chung Hsing University
2023
Women's Hospital
2004-2023
China Medical University
2004-2010
National Academy of Medicine
2008
Abstract Background Several studies have demonstrated that iDAScore is more accurate in predicting pregnancy outcomes cycles without preimplantation genetic testing for aneuploidy (PGT-A) compared to KIDScore and the Gardner criteria. However, effectiveness of with PGT-A has not been thoroughly investigated. Therefore, this study aims assess association between artificial intelligence (AI)-based (version 1.0) single-embryo transfer (SET) PGT-A. Methods This retrospective was approved by...
Current semen analysis still commonly depends on a manual microscopy method in clinical laboratories worldwide. However, some of the major disadvantages this technique are that it is labour-intensive, subjective, laboratory-based and time-consuming. Although computer-assisted analysers (CASAs) have enabled partial automation routine analysis, they lack wider acceptance due to their complicated operation. Therefore, development an accessible, rapid standardised for urgently needed. Here, we...
Recently, reports showed that embryos identified as mosaic after preimplantation genetic testing for aneuploid (PGT-A) could result in live birth with lower pregnancy and higher loss rates compared euploid embryos. However, the effects of mosaicism level on reproductive outcomes remain controversial. This study aimed to examine outcomes. Single embryo transfer was offered 108 women who only had Mosaic were labeled by utilizing next generation sequencing (NGS) based PGT-A day 5/6...
: To evaluate the effect of intrauterine infusion and hysteroscopic injection autologous platelet-rich plasma (PRP) in patients with a persistent thin endometrium (EM) undergoing euploid frozen embryo transfer (EFET) cycles.
Blastocysts were cryopreserved by a new two-step ultra-rapid cooling in super-cooled liquid nitrogen (-205 degrees C).There 308 mouse blastocysts collected from fertile B6CBF1 mice and 249 human 51 couples treated with IVF. The Vit-Master cryoloops after treatment 50 100% vitrification solution (VS) for 2 min 30 s, respectively. VS was composed of 20% ethylene glycol, dimethylsulphoxide 0.5 mol/l sucrose tubular fluid medium serum albumin. embryos warmed 0.25 0.125 3 min, survival observed...
This study was designed to assess the capability of ovarian reserve markers, including baseline FSH levels, anti-Müllerian hormone (AMH) and antral follicle count (AFC), as predictors live births during IVF cycles, especially for infertile couples with advanced maternal age and/or male factors.A prospective cohort 336 first IVF/ICSI cycles undergoing a long protocol GnRH agonist investigated. Patients endocrine disorders or unilateral ovaries were excluded.Among tests, AMH had greater area...
Sleep disturbance is a common issue that can arise from emotional distress. Women who received the complicated invasive in-vitro fertilization (IVF) procedures be stressful. The purpose of this study to understanding association between distress (measured as anxiety and depression) sleep quality for women undergoing IVF treatment. This research was cross-sectional questionnaire design. Questionnaires were completed during controlled ovarian hyperstimulation A total 97 participants complete...
This study evaluated the effectiveness of intraovarian platelet-rich plasma (PRP) injection in improving ovarian response and embryo quality IVF patients with poor previous controlled hyperstimulation (COH) cycles. 74 participated, 30 control group 44 PRP group. was injected during follicular phase for The completed two COH cycles, while underwent cycles before after injection. In first cycle, there were no significant differences between groups. However, second showed improvements: number...
Background Matrix metalloproteinases (MMPs) and tissue inhibitors of (TIMPs) are critical regulators extracellular matrix (ECM) proteolysis play a pivotal role in trophoblast invasion during embryo implantation. This study aimed to investigate the effects single-nucleotide polymorphisms (SNPs) MMP TIMP genes on clinical outcomes women undergoing vitro fertilization (IVF). Methods retroprospective included 1014 their first fresh IVF cycle without donor eggs at Lee Women’s Hospital between...
This retrospective analysis compared the efficiency of gonadotropin- releasing hormone (GnRH) antagonist (GnRH-ant) protocol and GnRH agonist long (GnRH-a) for patients with diminished ovarian reserve (DOR). A total 1,233 DOR (anti-Mullerian <1.1 ng/mL) were recruited this case-control study. They divided into two groups according to female age. Younger assigned POSEIDON group3 (PG3: age ≤35 years); older group 4 (PG4: >35 years). All underwent controlled stimulation fresh embryo transfer...
The primary objective of this study was to investigate whether preimplantation genetic testing for aneuploidy (PGT-A) blastocysts through array comparative genomic hybridization (aCGH) improves live birth rates (LBR) in IVF cycles patients with high prevalence aneuploidy. This included 1389 aCGH results derived from 296 PGT-A advanced maternal age (AMA) (n = 87, group A), those repeated implantation failure (RIF) 82, B), recurrent miscarriage (RM) C), and oocyte donors (OD) 45, young age, as...
The early development of the gut microbiome is governed by multiple factors and has significantly long-term effects on later-in-life health. To minimize inter-individual variations in environment, we determined developmental trajectories 28 healthy neonates during their stay at a postpartum center. Stool samples were collected three time points: first-pass meconium within 24 h life, 7 days age. Illumina sequencing V3-V4 region 16S rRNA was used to investigate microbiota profiles. We found...
Scand J Caring Sci; 2010; 24; 507–513 Grief Responses and coping strategies among Infertile Women after failed in vitro fertilization Treatment Reproductive technology has increased the childbearing potential for many infertile women, but (IVF) failures are common, which often trigger grief responses to manage stressful life event. The present cross-sectional study investigated 66 women who had experienced at least one failure with IVF treatment. data were gathered by a self-administered...