A5067395679- Reconstructive Surgery and Microvascular Techniques
- Head and Neck Surgical Oncology
- Reconstructive Facial Surgery Techniques
- Molecular Biology Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Innovations in Medical Education
- Orthopedic Infections and Treatments
- Bone fractures and treatments
- Craniofacial Disorders and Treatments
- History of Medical Practice
- Surgical Simulation and Training
- Cancer Immunotherapy and Biomarkers
- Facial Nerve Paralysis Treatment and Research
- Sarcoma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Anatomy and Medical Technology
- Dental Education, Practice, Research
- Oral Health Pathology and Treatment
- Cleft Lip and Palate Research
- Medical and Biological Sciences
Ente Ospedaliero Ospedali Galliera
2017-2024
Oral squamous cell carcinoma (OSCC) accounts for approximately 90% of oral malignancies and has a 5-year mortality rate close to 50%. A consistent part (70%) all cancers is diagnosed at an advanced stage since available screening techniques are ineffective. Therefore, it would be urgent improve them. The diagnostic gold standard tissue biopsy with histological immunohistochemical assessment. This method presents some limitations. Biopsy invasive the histopathological evaluation...
This study is a retrospective analysis of our experience in microsurgical bone transfers for complex limb reconstructions. The aim this to evaluate reliability the vascularized fibula technique: infection recurrence, hypertrophy, time union, complications, and healing severe osteomyelitis (Cierny-Mader III IV) cases over 38 93 month follow-up.From March 2010 until December 2015, 18 patients' limbs (6 females 1 2 males; mean age 48.7 years) were reconstructed with 10 free flaps, 5 pedicled 3...
Abstract Extended tumor resection in the middle third of face leads to complex defects: wide, 3-dimensional, and multitissutal. Appropriate reconstruction is challenging but mandatory obtain a functional aesthetic outcome for preservation an acceptable quality life. Three-dimensional combined flaps multistep procedures concur reach this scope. This exemplified on treatment invasive recurrent skin malignancy involving cheek maxillary bone association with full-thickness nasal defect....
Iacoviello, Paolo MD; Da Rold, Mariano Romeo, Antonella DDS; Gramegna, Marco Chiodi, Stefano Mattioli, Beniamino Mazzoni, Luca Tavakkoli, Alice Cardillo, Giovanni Audino, Signorini, Giuseppe Costanzo, Domenico MD Author Information
Background: An adequate OSCC macroscopic resection margin (MRM) is essential for effective treatment. This study analyzed the effects of formalin fixation (FF) on MRM. Material and Methods: A total 42 patients were enrolled in this study. Tumors from floor mouth (FOM; n = 23), tongue (TC; 10), maxilla (MT; 9) studied. 3D scanner was used to create virtual models, further analysis conducted according established protocol. Results: The most significant shrinkage observed TC (MRM 121; Med. 1.5...
Background For head and neck reconstructive procedures, free flap survival depends on microsurgical anatomical choices besides multimodal clinical management. The aim of the present study is to identify relevant variables for in our initial consecutive series. Methods A single-center, novel team surgical series was revised. outcome analyzed terms observing considered more relevant: type, recipient artery, vein(s), graft interposition were discussed facial thirds be reconstructed. Statistical...