Leonel Mendoza

ORCID: 0000-0002-7769-2151
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About
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Research Areas
  • Infectious Diseases and Mycology
  • Mycobacterium research and diagnosis
  • Fungal Infections and Studies
  • Plant Pathogens and Fungal Diseases
  • Actinomycetales infections and treatment
  • Plant Pathogens and Resistance
  • Antifungal resistance and susceptibility
  • Myxozoan Parasites in Aquatic Species
  • Oral and Maxillofacial Pathology
  • Veterinary Oncology Research
  • Yeasts and Rust Fungi Studies
  • Fungal Biology and Applications
  • Immunotherapy and Immune Responses
  • Microbial infections and disease research
  • Cervical Cancer and HPV Research
  • Milk Quality and Mastitis in Dairy Cows
  • Nail Diseases and Treatments
  • Plant Disease Resistance and Genetics
  • Plant-Microbe Interactions and Immunity
  • Polysaccharides and Plant Cell Walls
  • Escherichia coli research studies
  • T-cell and Retrovirus Studies
  • Leptospirosis research and findings
  • Insect symbiosis and bacterial influences
  • Bartonella species infections research

Michigan State University
2012-2024

Michigan United
2019-2024

CS Diagnostics
2008-2024

SUNY Downstate Health Sciences University
2020

State University of New York
2020

Florida Aquarium
2016

Instituto Lauro de Souza Lima
2007

New York University
2007

Harbor Branch Oceanographic Institute
2007

Colorado State University
2007

Paracoccidioidomycosis (PCM) is a systemic disease endemic to most of Latin America, with greatest impact in rural areas. The taxonomic status one the best studied Paracoccidioides isolates (Pb01) as P. brasiliensis remains unresolved due its genomic differences from other three previously described phylogenetic species (S1, PS2 and PS3; Carrero et al., 2008. Fungal Genet. Biol. 45, 605). Using genealogic concordance method recognition (GCPSR) via maximum parsimony Bayesian analysis, we...

10.1016/j.ympev.2009.04.005 article EN publisher-specific-oa Molecular Phylogenetics and Evolution 2009-04-18

Pythium insidiosum sp. nov., the etiologic agent of pythiosis, a cosmopolitan disease horses, cattle, and dogs, is described illustrated.

10.1128/jcm.25.2.344-349.1987 article EN Journal of Clinical Microbiology 1987-02-01

Abstract Objectives Human pythiosis is a life-threatening disease for which no standard treatment protocols with proven efficacy exist. We present the results of our institutional protocol, composed surgery, antifungal agents, iron chelator (only vascular cases) and immunotherapy. Methods retrospectively analysed patients ocular in King Chulalongkorn Memorial Hospital from April 2003 to May 2013. Fisher's exact test Wilcoxon's rank-sum were used. The MICs seven agents combination drugs...

10.1093/jac/dkv008 article EN Journal of Antimicrobial Chemotherapy 2015-01-27

ABSTRACT Lacazia loboi is the last of classical fungal pathogens to remain a taxonomic enigma, primarily because it has resisted cultivation and only causes cutaneous subcutaneous infections in humans dolphins New World tropics. To place evolutionary tree life, as been done for other enigmatic human Pneumocystis carinii Rhinosporidium seeberi , we amplified its 18S small-subunit ribosomal DNA (SSU rDNA) 600 bp chitin synthase-2 gene. Our phylogenetic analysis indicated that L. sister taxon...

10.1128/jcm.39.1.309-314.2001 article EN Journal of Clinical Microbiology 2001-01-01

We describe the ecological niche of human and animal pathogen Pythium insidiosum within endemic agricultural areas Thailand. Samples were collected from irrigation water, including rice paddy fields, channels reservoirs. Zoospores P. captured water by use a sterile hair baiting technique. isolates identified based on phenotypic characteristics using specific PCR assay for insidiosum. In addition, internal transcribed spacer (ITS) regions rDNA sequenced used in phylogenetic analysis 20 other...

10.1080/13693780701513840 article EN Medical Mycology 2008-01-01

10.1007/s12281-013-0144-z article EN Current Fungal Infection Reports 2013-06-04

Ever since the uncultivated South American fungal pathogen Lacazia loboi was first described 90 years ago, its etiology and evolutionary traits have been at center of endless controversies. This infects skin humans as long believed, dolphin skin. However, recent DNA analyses infected dolphins placed sequences within Paracoccidioides species. came a surprise suggested human pathogens may be different In this study, population genetic from four grouped in monophyletic cluster sister to P....

10.1038/s41598-021-97429-7 article EN cc-by Scientific Reports 2021-09-13

Culture filtrate antigens of Basidiobolus ranarum and Conidiobolus coronatus were analyzed by immunodiffusion (ID) with homologous rabbit antisera. B. C. each found to have five specific antigens. Results tests heterologous antisera indicated that all the species shared at least one antigen. ID incorporating precipitin bands as references developed for detection basidiobolomycosis conidiobolomycosis. These performed sera from humans horses proven conidiobolomycosis well control animals...

10.1128/jcm.28.9.1887-1890.1990 article EN Journal of Clinical Microbiology 1990-09-01

Abstract Cutaneous granulomas in dolphins were believed to be caused by Lacazia loboi, which also causes a similar disease humans. This hypothesis was recently challenged reports that fungal DNA sequences from grouped this pathogen with Paracoccidioides brasiliensis. We conducted phylogenetic analysis of fungi 6 bottlenose (Tursiops truncatus) cutaneous and chains yeast cells infected tissues. Kex gene P. brasiliensis showed 100% homology cultivated brasiliensis, 73% those L. 93% lutzii....

10.3201/eid2212.160860 article EN cc-by Emerging infectious diseases 2016-10-27

A practical, sensitive, and specific immunodiffusion test was developed for diagnosing monitoring pythiosis in horses. Culture filtrates, a soluble cell mass, trypsinized Pythium sp. antigens were evaluated against prepared rabbit anti-Pythium serum horse case sera. The culture filtrate demonstrated the greatest capacity detecting precipitins stability during storage. In contrast, had weakest capability multiple poorest stability. 13 sera from horses with proven active positive tests...

10.1128/jcm.23.5.813-816.1986 article EN Journal of Clinical Microbiology 1986-05-01

Summary. Cladosporium carrionii, Fonsecaea pedro‐soi and Phialophora uerrucosa , the three most important agents of chromoblastomycosis, produced large numbers sclerotic bodies at 25 °C, greater 37 after inoculation into a defined pH 2.5 medium containing 0.1 mmol I ‐1 Ca 2 + . Higher concentrations reversed this tendency promoted maintenance hyphal growth. Addition 2+ chelator EGTA to same buffered 6.5 also induced bodies, but in more concentration‐dependent fashion. 0.5–1.0 maximum Cl....

10.1111/j.1439-0507.1993.tb00744.x article DE Mycoses 1993-05-01

10.1111/j.2042-3306.1990.tb04273.x article EN Equine Veterinary Journal 1990-07-01

Two outbreaks of zigomycosis with rhinofacial and two other rhinopharyngeal lesions involving fungi filamentous coaenocytic hyphae characteristic entomoph-thoramycetous are reported in the state Paraíba, northeastern Brazil. One outbreak zygomycosis occurred during rainy season affecting 5 sheep. Another clinical form affected one out 40 sheep dry season. Common signs infection were bilateral serosanguineous nasal discharge swelling nostrils, upper lip, skin face. At necropsy mucosa showed...

10.1590/s0100-736x2008000100005 article EN cc-by Pesquisa Veterinária Brasileira 2008-01-01
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