A5065598007- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Neuroscience and Neural Engineering
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Ion channel regulation and function
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Healthcare Systems and Public Health
- Streptococcal Infections and Treatments
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
British Heart Foundation
2024
King's College London
2024
National Institute for Health Research
2024
St Thomas' Hospital
2024
East Surrey Hospital
2022
St George's Hospital
2020
St George's Hospital
2020
Imperial College London
2014-2019
St George’s University Hospitals NHS Foundation Trust
2019
Abstract Aims The aim of this study was to understand the changing trends in atrial fibrillation (AF) incidence and mortality across Europe from 1990 2017, how socioeconomic factors sex differences play a role. Methods results We performed temporal analysis data 2017 Global Burden Disease Database for 20 countries using Joinpoint regression analysis. Age-adjusted incidence, mortality, mortality-to-incidence ratios (MIRs) approximate case fatality rate are presented. Incidence were...
Abstract Aims To assesses trends in rheumatic heart disease (RHD) burden high-income, European Union 15+ (EU15+) countries between 1990 and 2019. Methods results Cross-sectional analysis of the incidence mortality RHD was conducted using data from Global Burden Disease (GBD) Study database. Age-standardized rates (ASIRs) age-standardized (ASMRs) were extracted for EU15+ per sex each years to 2019, inclusive, mortality-to-incidence indices (MII) computed. Joinpoint regression used description...
Heart failure with preserved ejection fraction (HFpEF) is a common condition few effective therapies and hence represents major healthcare burden. The clinical syndrome of HFpEF can be caused by varying pathophysiological processes, coronary microvascular dysfunction (CMD) proposed as one the aetiologies, although confirming causality has been challenging. CMD characterised inability vasculature to augment blood flow in response physiological stressor established driver angina patients...
Abstract Background Atrial fibrillation (AF) is one of the most common arrhythmias found in general population, carrying risk associated cardiovascular and cerebrovascular complications, presenting a significant global health burden. Better understanding its epidemiology may have public implications. Purpose To describe trends AF incidence mortality throughout Europe from 1990 to 2017. Methods We performed temporal analysis data deposited Global Burden Disease Study Database for countries...
<h3>Introduction</h3> Pulmonary vein isolation (PVI) is a commonly used element in treatment of atrial fibrillation (AF) but has never been tested an intentionally placebo (sham) controlled trial. Nevertheless there have several randomized trials (RCTs) which both arms receive ablation procedure the only difference between inclusion or omission PVI. As long as doctor and patient reason to believe that procedures are effective, such RCTs could be effective proxy for trials. <h3>Methods</h3>...
Abstract Background Valvular heart disease is common globally; mitral regurgitation the most valve pathology in general population and subsequently second frequent indication for surgery Europe. Whilst European epidemiology of aortic stenosis well elucidated literature, no Europe-wide study has been undertaken to identify trends incidence mortality secondary non-rheumatic degenerative disease. Purpose Our aim describe throughout Europe from 1990 2019. Methods We performed a temporal analysis...