- Epilepsy research and treatment
- Metabolism and Genetic Disorders
- Neuroscience and Neuropharmacology Research
- Liver Disease Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Neonatal and fetal brain pathology
- Diet and metabolism studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Hemoglobinopathies and Related Disorders
- Infant Development and Preterm Care
- Folate and B Vitamins Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Neurological and metabolic disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Cardiac pacing and defibrillation studies
- Skin Protection and Aging
- Apelin-related biomedical research
- Tracheal and airway disorders
- Maternal and fetal healthcare
- Retinopathy of Prematurity Studies
- Neonatal skin health care
- Advancements in Transdermal Drug Delivery
- Growth Hormone and Insulin-like Growth Factors
- Data-Driven Disease Surveillance
Al-Azhar University
2016-2024
Zagazig University
2024
Al-Azhar University
2018-2021
National Heart Institute
2018
Online Technologies (United States)
2018
Zika virus infection in humans has been linked to severe neurological sequels and foetal malformations. The rapidly evolving epidemics serious complications made the frequent updates of mandatory. Web search query emerged as a low-cost real-time surveillance system anticipate infectious diseases' outbreaks. Hence, we developed prediction model that could predict Zika-confirmed cases based on volume Google Trends. We extracted weekly confirmed two epidemic countries, Brazil Colombia. got...
Abstract Background Ectopic visceral fat is a major risk factor for obesity complications including insulin resistance and metabolic syndrome. Ultrasonography simple bedside screening tool used the assessment of ectopic fatty pancreas. This study investigates association between resistance, syndrome pancreas detected by ultrasound in children with obesity. Methods case-control included 50 prepubertal obese (body mass index [BMI] ≥95th age- sex-specific percentiles) 30 lean (BMI 5th–85th as...
Uncertainty still exists regarding the role of some environmental risk in development type 1 diabetes mellitus (T1DM) both globally and Egypt. The objective here was to explore potential factors associated with T1DM among children A case-controlled study 204 an equal number age sex-matched controls conducted Assiut, Data parental, gestational, neonatal, childhood possible for were evaluated. final sex adjusted multivariable logistic regression model revealed that significantly higher rural...
Children with epilepsy have a high incidence of attention deficit hyperactivity disorder (ADHD). Oxidation stress and disturbed neurotransmitters are suggested mechanisms; however, their role is not fully explored. This study evaluates the association between circulating malondialdehyde as an oxidation marker, apelin neuropeptide, ADHD in children epilepsy. Fifty unknown etiology, which 25 ADHD, well 35 healthy were included. Serum levels estimated. We investigated seizure severity, response...
Epilepsy is a heterogeneous disorder that not limited to experiencing seizures but also includes multiple neuropsychiatric squeal (i.e. attention-deficit/hyperactivity (ADHD), depression and anxiety) adversely impact child quality of life. However, the underlying mechanism linking both disorders yet thoroughly explored. Our objective was assess pro-inflammatory cytokines levels in children with seizure controlled epilepsy explore association between co-occurrence ADHD such children. A...
Objective: Excessive salivation and drooling are distressing problems that affect both children their families. Salivary gland botulinum toxin injection is a widely studied therapeutic method for treating sialorrhea. The proper protocol such treatment modality an area of interest researchers. This study set out to assess the success ultrasound-guided injections in either submandibular or combined with parotid salivary glands cerebral palsy suffering from sialorrhea, while also identifying...
Cognitive impairment is a common consequence of epilepsy in children. This study aimed to assess the ratio omega-6 omega-3 fatty acid levels and its impact on cognitive function children with idiopathic epilepsy. We performed case-control 30 20 healthy measured alpha-linolenic (omega-3) linoleic (omega-6) by means gas-liquid chromatography. assessed Arabic version fourth edition Stanford-Binet test P300 component event-related potentials. All had an intelligent quotient greater than 70....
Abstract Inflammatory processes are increasingly attributed to macrophage polarization. Proinflammatory macrophages promote T helper (Th) 1 response, tissue repair, and Th2 responses. Detection of in sections is facilitated by CD68. Our study focused on the expression CD68 estimation proinflammatory cytokines children’s patients with chronic tonsillitis secondary vitamin D supplementation. This hospital-based Randomized prospective case–control was conducted 80 children associated deficiency...
The purpose of this study was to illustrate the association between vascular endothelial growth factor level and pulmonary artery hypertension in children with β-thalassemia major.This case-control conducted on 116 major; 58 them had hypertension. They were compared healthy who age sex-matched (control group). Serum levels echocardiographic assessment done for all children.Vascular serum significantly higher major than those without hypertension, as well control groups (p<0.001). Vascular a...
Sleep disordered breathing (SDB) represents common comorbidities of childhood obesity leading to interrupted sleep and deprivation. deprivation alters secretion brain-derived neurotrophic factor (BDNF), which is an appetite regulator. However, little known about the relation between BDNF central in children with SDB. The aim study was evaluate level anthropometric indices SDB obesity.A prospective case-control conducted on 30 (BMI > 95th percentile) healthy lean 5th-85th percentile)....
The purpose of this study was to illustrate the association between vascular endothelial growth factor level and pulmonary artery hypertension in children with β‐thalassemia major. This case–control conducted on 116 major; 58 them had hypertension. They were compared healthy who age sex‐matched (control group). Serum levels echocardiographic assessment done for all children. Vascular serum significantly higher major than those without hypertension, as well control groups (p < 0.001). a...
El deterioro cognitivo es una consecuencia común de la epilepsia en niños. objetivo del estudio fue evaluar el cociente los niveles ácidos grasos omega-6 y omega-3 su impacto funcionamiento niños con idiopática. Estudio casos controles 30 idiopática 20 sanos. Se midieron plasmáticos ácido alfa-linolénico (omega-3) linoleico (omega-6) mediante cromatografía gases. se evaluó versión árabe cuarta edición escala Stanford-Binet onda P300 potenciales relacionados eventos. Todos participantes...
Children with congenital heart disease (CHD) who have relevant systemic-to-pulmonary shunts will develop pulmonary hypertension (PH) if untreated. With advances in medical research, new biomarkers representing different physiological processes continue to emerge, providing an ever clearer risk profile for patients PH. To evaluate the role of serum galectin-3 and fatty acid binding protein (H-FABP) as early predictive PH children ventricular septal defect (VSD). The study included 50 VSD; 24...
Background: Morbidly adherent placenta is a dangerous pregnancy syndrome that becoming more well acknowledged as cause in rising incidence of maternal morbidity and mortality. In an effort to improve the mother's fetus's health. This study amid determine risk factors, outcome morbidly at Zagazig maternity hospital quality health mother fetus. Methods: recorded Interventional cohort was conducted attending antenatal care unit or emergency department Maternity Hospital. included pregnant Women...
Abstract Background Thiamine deficiency is commonly reported in patients with diabetes especially during diabetic ketoacidosis (DKA) that could attribute to myocardial dysfunction those patients. However, there limited data regarding its relation function among This study aimed explore the association between and serum thiamine levels children type 1 mellitus (DM). Methods cross-sectional comparative included 25 DKA. Clinical assessment, echocardiographic examination measurement of...
Children are frequently exposed to significant hazard for organophosphate poisoning (OP) in their environment; since the brain is growing during this period and it extra liable neurotoxicants. The aim of work was determine relationship between urinary concentrations dialkylphosphates (DAP) metabolites, which biomarkers OP pesticide exposure, attention-deficit/hyperactivity disorder (ADHD) Egyptian children ages seven twelve years. A case-control study conducted at Alzhraa University...
Background: Adenoid surface in patients suffering from secretory otitis media is usually associated with bacterial biofilm.Adenoidectomy thought to be effective treatment of cases media.Aim the study: : To Evaluat role adenoidectomy alone or combination ventilation tube insertion improving outcome OM effusion adenoid hypertrophy.Patients and Methods: This study included 40 children recurrent persistent despite proper medical for 3-6 months.They were divided into 2 equal groups.Group A...