A5068147595- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Heart Failure Treatment and Management
- Peripheral Artery Disease Management
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Orthopaedic implants and arthroplasty
- Acute Ischemic Stroke Management
- Cardiac Arrhythmias and Treatments
- Total Knee Arthroplasty Outcomes
- Mechanical Circulatory Support Devices
- Breast Implant and Reconstruction
- Vascular Procedures and Complications
- Cardiac Arrest and Resuscitation
- Blood properties and coagulation
- Aortic Disease and Treatment Approaches
- Inflammatory Biomarkers in Disease Prognosis
Mansoura University
2025
Ministry of Health and Population
2025
Freeman Hospital
2020-2024
University of Hertfordshire
2015-2024
Montefiore Health System
2024
Armed Forces College of Medicine
2023-2024
Fayoum University
2020-2024
Hammersmith Hospital
2022-2023
Imperial College Healthcare NHS Trust
2022-2023
Newcastle University
2021-2023
AimsThe endogenous fibrinolytic system serves to prevent lasting thrombotic occlusion and infarction following initiation of coronary thrombosis. We aimed determine whether impaired fibrinolysis can identify patients with ST-segment elevation myocardial (STEMI) who remain at high cardiovascular risk despite dual antiplatelet therapy (DAPT).
Objectives: To analyze pediatric vascular injury patterns, the interventions performed, and subse-quent outcomes at a high-volume trauma center.Methods: This study is retrospective review of patients, who were admitted to Uni-versity Emergency Hospital between 2010 2020 with an International Classification 9th Dis-eases –Revision code for traumatic (900.0 – 904.9). Results: During period, 217 patients (mean age 12± 6, 135 (62%) males) sustained vascu-lar injuries.. Upper extremity...
Background and Objectives: Primary liver cancer is a major cause of mortality, ranking third among the most fatal cancers. In Egypt, constitutes 11.75% gastrointestinal malignancies, with HCC representing 70.5% cases. The landscape management was revolutionized by locoregional modalities, which offer comparable alternative to conventional techniques, low complications minimal invasiveness. RFA technique that suitable for early-stage lesions in liver, high overall survival complication rates....
Background: Diabetic patients tend to have complex coronary artery disease (CAD). Understanding their procedural risk may help guiding treatment strategies. Syntax and British Cardiovascular Intervention Society) Jeopardy Score (BCIS-JS) been used define CAD but not compared in diabetic patients. Methods: This is a retrospective analysis of prospectively collected data consecutive who underwent percutaneous intervention (PCI) were deemed unsuitable for surgical revascularization. Both syntax...
Cardiovascular disease is the primary cause of mortality and morbidity in patients with chronic kidney (CKD), particularly those end stage renal (ESRD) undergoing hemodialysis. This paper examines challenges managing acute coronary syndrome (ACS) ESRD patients, focusing on delicate balance between thrombotic bleeding risks. The review explores mechanisms underlying increased risk ESRD, including elevated platelet aggregation, endothelial dysfunction, alterations coagulation factors....
Abstract The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated opiates, which may delay gastric transit reduce DAPT absorption. We sought to assess the effect morphine on reperfusion, infarct size thrombotic status in 300 patients presenting for PPCI. Morphine was given a non-randomized fashion as required by teams en route heart attack...
Malaria has been appraised as a significant vector-borne parasitic disease with grave morbidity and high-rate mortality. Several challenges have confronting the efficient diagnosis treatment of malaria.
Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which strongly relates improved functional outcome. The impact oral anticoagulants on fibrinolysis is unknown. Our aim was test the hypothesis that apixaban enhances in non-valvular atrial fibrillation (NVAF).In a prospective cross-sectional analysis, we compared NVAF (n = 180) taking aspirin, warfarin, or apixaban. In longitudinal study, were tested before and...
Optimal myocardial reperfusion during primary percutaneous coronary intervention (pPCI) is increasingly recognized to be beyond restoring epicardial flow. Both invasive and non-invasive tools have highlighted the limitation of using this metric, more efforts are focused towards achieving optimal at level microcirculation. Recent data close relationship between thrombus burden impaired microcirculation in patients presenting with ST-segment elevation infarction (STEMI). Moreover, distal...
Remote ischaemic conditioning (RIC) has been shown to reduce myocardial infarct size in animal models of infarction. Platelet thrombus formation is a critical determinant outcome ST-segment elevation infarction (STEMI). Whether the beneficial effects RIC are related thrombotic parameters unclear.In substudy Effect Ischaemic Conditioning on clinical outcomes STEMI patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI) trial, we assessed effect status. Patients presenting...
Heart failure is heterogeneous in aetiology, pathophysiology, and presentation. Despite this diversity, clinical trials of patients hospitalized for HF deal with problem as a single entity, which may be one reason repeated failures. The first EuroHeart Failure Survey screened consecutive deaths discharges suspected heart during 2000–2001. Patients were sorted into seven mutually exclusive hierarchical presentations: (1) cardiac arrest/ventricular arrhythmia; (2) acute coronary syndrome; (3)...
Non-vitamin K antagonist oral anticoagulants (NOACs) reduce the risk of thromboembolism in patients with atrial fibrillation (AF). There has been no head-to-head comparison effect these agents on ex vivo thrombotic and thrombolytic status. Enhanced platelet reactivity impaired endogenous thrombolysis are factors for recurrent events. We aimed to assess comparative NOACs warfarin using an test thrombosis thrombolysis. Eighty newly diagnosed non-valvular AF were tested before, after being...
Background Patients with ST-elevation myocardial infarction (STEMI) exhibit pro-thrombotic and pro-inflammatory states. Markers of enhanced platelet reactivity inflammation are predictive adverse outcome. However, the relationship between these biomarkers, their combined usefulness for risk stratification, is not clear. Methods In a prospective study 541 patients presenting STEMI, blood samples were taken on arrival to measure high-sensitivity C-reactive protein (hs-CRP),...