- Luminescence Properties of Advanced Materials
- Nanoplatforms for cancer theranostics
- Nanoparticles: synthesis and applications
- Radiation Detection and Scintillator Technologies
- Photodynamic Therapy Research Studies
- Hemoglobin structure and function
- biodegradable polymer synthesis and properties
- Silk-based biomaterials and applications
- Boron Compounds in Chemistry
- Advanced biosensing and bioanalysis techniques
- Carbon Nanotubes in Composites
- Drug Solubulity and Delivery Systems
- Bee Products Chemical Analysis
- Quantum and electron transport phenomena
- Magneto-Optical Properties and Applications
- Erythrocyte Function and Pathophysiology
- Dyeing and Modifying Textile Fibers
- Enzyme Production and Characterization
- Proteins in Food Systems
- Carbon and Quantum Dots Applications
- Quantum Dots Synthesis And Properties
- Advanced Drug Delivery Systems
- Analytical Methods in Pharmaceuticals
- Spectroscopy Techniques in Biomedical and Chemical Research
- 3D Printing in Biomedical Research
Saratov State University
2022-2025
Saratov State Medical University
2022-2024
Institute of Physics
2024
Control of spin wave transport in polymer 3D films was realized by magnetic microvolcanoes embedded waveguides, fabricated soft-matter specific techniques. Propagate the signal excited yttrium iron garnet (YIG) with self-standing chambers on top filled nanoparticles evaluated Brillouin light scattering and microwave spectroscopy. The moment varied change field bias direction inside YIG films, which shown 2D mapping outer surface films. good correlation micromagnetic modeling experimental...
Cell spheroids (CSs) are three-dimensional models in vitro that have a microenvironment similar to tissues. Such cellular structures of great interest the field nano biomedical research, as they can simulate information about characteristics nanoparticles (NPs) by avoiding use laboratory animals. Due development areas such bioethics and tissue engineering, it is expected 3D cell will become an even more valuable tool hands researchers. We present overview carbon nanotubes (CNTs) research on...
Inflammatory dermatoses represent a global problem with increasing prevalence and recurrence among the world population. Topical glucocorticoids (GCs) are most commonly used anti-inflammatory drugs in dermatology due to wide range of their therapeutic actions, which, however, have numerous local systemic side effects. Hence, there is growing need create new delivery systems for GCs, ensuring drug localization pathological site, thus effectiveness therapy lowering risk Here, we propose novel...
Hybrid carriers with the mineral CaCO3/Fe3O4 core and protein-tannin shell are attractive for drug delivery applications due to reliable coupling of anticancer drugs complex possibility remote control over localization by external magnetic field. This study aims elucidate mechanisms release via enzymatic degradation a carrier triggered proteolytic hydrolases trypsin pepsin under physiological conditions. To do this, were incubated enzyme solutions in special buffers maintain activity. The...
Three-dimensional (3D) spheroid cell cultures of fibroblast (L929) and tumor mammary mouse (4T1) were chosen as in vitro tissue models for imaging ternary AgInS/ZnS fraction quantum dots (QDs). We showed that the tissue-mimetic morphology spheroids through well-developed cell–cell cell–matrix interactions distinct diffusion/transport characteristics makes it possible to predict effect QDs on vital activity cells while simultaneously comparing with classical two-dimensional (2D) cultures. The...
The effect of an extremely low frequency alternating magnetic field (ELF AMF) at frequencies 17, 48, and 95 Hz 100 mT on free internalized 4T1 breast cancer cell submicron mineral carriers with anticancer drug, mitoxantrone, was shown. (100 mT; Hz; time treatment—10.5 min a 30 s delay) does not lead to the significant destruction carrier shells release mitoxantrone or bovine serum albumin from them according data spectrophotometry, heating in process exposure fields. most optimal set factors...
The present work demonstrates the assessment of cytotoxicity upconversion nanoparticles (UCNPs) coated by SiO<sub>2</sub> on different normal and cancer murine cell lines in vitro. viability is scored for cytotoxic effects UCNPs at dark conditions. silica shells provide a dose-dependent effect all studied which was most pronounced Raw264.7 line. It probably caused high phagocytic activity macrophages. less sensitive line 4T1. statistically significant differences after 24 48 h incubation...
Carriers based on upconversion nanoparticles (UCNPs) and cyanine dye are suitable for theranostic application in oncology, although care must be taken selection of the surface coating material, UCNP charge, size, dosage material. Investigation influence annealing temperature particles luminescence properties cytotoxic effect relevant. The present work demonstrates assessment cytotoxicity UCNPs unannealed annealed at 550 oC different normal cancer murine cell lines vitro. viability is scored...