A5077876991- Machine Learning in Healthcare
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
- Chromosomal and Genetic Variations
- Retinal Imaging and Analysis
- Tactile and Sensory Interactions
- Social Robot Interaction and HRI
- RNA Research and Splicing
- Genomics and Phylogenetic Studies
- Colorectal Cancer Screening and Detection
- Plant Molecular Biology Research
- Artificial Intelligence in Healthcare
- PI3K/AKT/mTOR signaling in cancer
- Bayesian Methods and Mixture Models
- Machine Learning and Data Classification
- Health Promotion and Cardiovascular Prevention
- Evolutionary Psychology and Human Behavior
- Face Recognition and Perception
- Plant Gene Expression Analysis
- Machine Learning and ELM
- Face recognition and analysis
- Mental Health via Writing
- Visual perception and processing mechanisms
- Photosynthetic Processes and Mechanisms
- Medicinal Plant Research
Liaoning University
2024
Northeast Normal University
2022-2023
Kyoto University
2023
Okayama University
2019-2021
Laboratoire de Probabilités et Modèles Aléatoires
2020
Laboratoire de Probabilités, Statistique et Modélisation
2020
Université Paris Cité
2019
University of Rochester Medical Center
2006
Vanderbilt University
1999
Howard Hughes Medical Institute
1998
Myocyte enhancer factor 2 (MEF2) transcriptional regulatory proteins are key regulators of muscle-specific gene expression and also play a general role in the cellular response to growth factors, cytokines environmental Stressors. To identify signaling pathway components that might mediate these events, potential MAP kinase PKC modulation MEF2A phosphorylation activity were therefore studied. In transient transfection reporter assays, activated p38 potently increased trans -activating...
5-fluorouracil (5FU) is an effective anti-cancer drug, yet its mechanism of action remains unclear. Here, we examine the effect 5FU on pre-mRNA splicing in vivo. Using RT-PCR, show that a number pre-mRNAs inhibited HeLa cells have been exposed to low dose 5FU. It appears this inhibitory not due incorporation into pre-mRNA, because partially or fully 5FU-substituted when injected Xenopus oocytes, spliced just as well unsubstituted pre-mRNA. Detailed analyses 5FU-treated indicate incorporated...
Abstract Background Analysis of the relationship between chromosomal structural variation (synteny breaks) and 3D-chromatin architectural changes among closely related species has potential to reveal causes correlates change chromatin remodeling. Of note, contrary extensive studies in animal species, pace pattern following speciation plants remain unexplored; moreover, there is little exploration occurrence synteny breaks context multiple genome topological hierarchies within same model...
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCo) has long been studied from many perspectives. As a multisubunit (large subunits [LSUs] and small subunits[SSUs]) protein encoded by genes residing in the chloroplast ( rbcL ) nuclear rbcS genomes, RuBisCo also is model for cytonuclear coevolution following allopolyploid speciation plants. Here, we genomic transcriptional coordination of auxiliary chaperonin chaperones that facilitate biogenesis across multiple natural artificially...
Associations between 3D chromatin architectures and epigenetic modifications have been characterized in animals. However, any impact of DNA methylation on architecture plants is understudied, which confined to Arabidopsis thaliana. Because plant species differ genome size, composition, overall packing, it unclear what extent findings from A. thaliana hold other species. Moreover, the incomplete architectural profiles low-resolution high-throughput chromosome conformation capture (Hi-C) data...
Many ophthalmic diseases such as age-Related macular degeneration can lead to central vision loss. Loss of reduce some cognitive abilities like reading, driving or face recognition. Training brain improve the ability people use their peripheral vision. Researchers have difficulty in finding enough subjects who loss ensure validity experiment. Central-scotoma simulator (A software simulate dark spot vision) patient's by which subject. In previous studies, central-scotoma based on eye tracker...
Touch shape discrimination is not only closely related to tactile mechanoreceptors but also higher cognitive function. However, previous methods are difficult complete in a short time, and the devices complicated operate user-friendly for nonprofessionals. Here, we propose new method, evaluation quantity of which angle threshold. In addition, make this method easy use nonprofessionals, designed haptic sorting system, including device software. To evaluate two-angle experiments were compared,...
With the advent of era artificial intelligence, more and robots appear in daily life. To better meet aesthetic needs public, appearance design robot becomes particularly important. Some researchers suggested that human beings have instinct to protect their offspring, which makes adults usually think infants as attractive likable adults. In addition, Lorentz et al. put forward baby schema (or Kindchenschema) summed up special features infants' face it may be reason why are different from make...
We introduce WildWood (WW), a new ensemble algorithm for supervised learning of Random Forest (RF) type. While standard RF algorithms use bootstrap out-of-bag samples to compute scores, WW uses these produce improved predictions given by an aggregation the all possible subtrees each fully grown tree in forest. This is achieved with exponential weights computed over samples, that are exactly and very efficiently thanks called context weighting. improvement, combined histogram strategy...
Macular disease patients who lost central vision must use their peripheral to read slowly. There are some assistive methods proposed improve reading experience. Sequence word display like RSVP suited the performance of low people because it can reduce crowding effect, limit visual span and do not need saccades. However, these in is satisfactory. This study aimed design a assistant system that uses new method by fixed gaze patient test effects software called NRSVP produced improvement...
Contrastive representation learning has been recently proved to be very efficient for self-supervised training. These methods have successfully used train encoders which perform comparably supervised training on downstream classification tasks. A few works started build a theoretical framework around contrastive in guarantees its performance can proven. We provide extensions of these results with multiple negative samples and multiway classification. Furthermore, we convergence the...