A5038194738- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Fungal Biology and Applications
- Sesquiterpenes and Asteraceae Studies
- Phytochemicals and Antioxidant Activities
- Synthesis and biological activity
- Metal complexes synthesis and properties
- Traditional and Medicinal Uses of Annonaceae
- Polysaccharides and Plant Cell Walls
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Analytical Chemistry and Chromatography
- Synthesis and Biological Evaluation
- Bioactive Natural Diterpenoids Research
- Plant Toxicity and Pharmacological Properties
- Asymmetric Synthesis and Catalysis
- Microbial Natural Products and Biosynthesis
- Synthetic Organic Chemistry Methods
- Tannin, Tannase and Anticancer Activities
- Medicinal plant effects and applications
- Metabolomics and Mass Spectrometry Studies
- Synthesis of Organic Compounds
- Phytochemical compounds biological activities
- Synthesis and Characterization of Heterocyclic Compounds
- Chemical Synthesis and Analysis
University of Belgrade
2013-2024
Institute of Chemistry, Technology and Metallurgy
2003-2024
Institute for Technology of Nuclear and other Mineral Raw Materials
1999-2015
University of Kragujevac
2014
Universität Greifswald
2006
Institute of Chemistry
1996
Mushrooms are experiencing a kind of renaissance as part the contemporary human diet. These valuable organisms more than food, they fit in perfectly novel market group known nutra-mycoceuticals. Immune-balancing mushroom dietary fibers and secondary metabolites such polyphenols main focus healthcare industry. Wellness cosmetic companies increasingly using extracts rich these ingredients. This review considers basic molecular immunomodulatory mechanisms action most commonly used fibers,...
Euphorbia nicaeensis All. belongs to the flowering plant family Euphorbiaceae. Our previous research has shown that latex of this species is a rich source jatrophane-type diterpenes. Due exceptional biological activities exhibited by these compounds, was extended root species. From roots E. nicaeensis, collected in Deliblato Sand (Serbia), diterpene from an extremely rare class lumiphorbol isolated for first time The structure compound determined spectroscopic techniques (1D and 2D NMR), as...
From the Montenegrin spurge Euphorbia dendroides, seven new diterpenoids [jatrophanes (1–6) and a tigliane (7)] were isolated their structures elucidated by spectroscopic techniques. The biological activity of compounds was studied against four human cancer cell lines. most effective jatrophane-type compound (2) its structurally closely related derivative (1) evaluated for interactions with paclitaxel doxorubicin using multi-drug-resistant line. Both exerted strong reversal potential...
A 1,7-bis(alkylamino)diazachrysene-based small molecule was previously identified as an inhibitor of the botulinum neurotoxin serotype light chain metalloprotease. Subsequently, a variety derivatives this chemotype were synthesized to develop structure−activity relationships, and all are inhibitors BoNT/A LC. Three-dimensional analyses indicated that half originally discovered 1,7-DAAC structure superimposed well with 4-amino-7-chloroquinoline-based antimalarial agents. This observation led...
Hot water extract (LN), partially purified polysaccharides (LP) and hot alkali extracted (LNa) obtained from fruiting bodies of the wild basidiomycete Laetiporus sulphureus were examined for their antioxidant activities. LNa was most active antioxidant, as shown by median effective concentrations (EC50 values) 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity (0.5 ± 0.2 mg/ml), reducing power (4.0 0.3 mg/ml) ferrous ion-chelating ability (1.5 0.1 mg/ml). contained highest level...
Three different polysaccharide extracts of a wild European source the mushroom Ganoderma lucidum were screened for their free radical-blocking potential, which could strengthen skin?s barrier function, and provide skinlightening effect via potential inhibition tyrosinase. The anti-collagenase anti-elastase activities, can help to restore skin elasticity tensile strength, also evaluated three extracts. Carbohydrates most abundant components extracts, followed by smaller quantities proteins,...
A study of secondary metabolites from the bark Alnus glutinosa led to isolation fourteen diarylheptanoids: oregonin (1), platyphylloside (2), rubranoside (3), B (4), hirsutanonol (5), hirsutenone (6), hirsutanonol-5-O-β-D-glucopyranoside (7), platyphyllonol-5-O-β-D-xylopyranoside (8), aceroside VII (9), alnuside (10), (11), 1,7-bis-(3,4-dihydoxyphenyl)-5-hydroxy-heptane-3-O-β-D-xylopyranoside (12), (5S)-1-(4-hydroxyphenyl)-7-(3,4-dihydroxyphenyl)-5-O-β-D-glucopyranosyl-heptan-3-one (13), and...