- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Organ and Tissue Transplantation Research
- Trauma Management and Diagnosis
- Nerve Injury and Rehabilitation
- Oral health in cancer treatment
- Cleft Lip and Palate Research
- Transplantation: Methods and Outcomes
- Organ Donation and Transplantation
- Spine and Intervertebral Disc Pathology
- Tracheal and airway disorders
- Head and Neck Cancer Studies
- Trigeminal Neuralgia and Treatments
- Facial Trauma and Fracture Management
- Pluripotent Stem Cells Research
- Orthopedic Surgery and Rehabilitation
- Diabetic Foot Ulcer Assessment and Management
- Mesenchymal stem cell research
- Mast cells and histamine
- Testicular diseases and treatments
- Ocular Oncology and Treatments
- Neurosurgical Procedures and Complications
- NF-κB Signaling Pathways
- Genomics, phytochemicals, and oxidative stress
- Facial Nerve Paralysis Treatment and Research
Chiayi Chang Gung Memorial Hospital
2008-2023
Fanjingshan National Nature Reserve
2023
Weatherford College
2022
Taipei Veterans General Hospital
2007-2014
National Yang Ming Chiao Tung University
2007-2014
Central South University
2014
National Yang Ming University Hospital
2007-2014
Hunan University of Traditional Chinese Medicine
2014
Chang Gung University
2001-2013
Taipei Tzu Chi Hospital
2013
Background: Microsurgical free tissue transfer has become a reliable technique. Nevertheless, 5 to 25 percent of transferred flaps require re-exploration due circulatory compromise. This study was conducted evaluate the timing occurrence flap compromise following transfer, and its correlation with salvage outcome. Methods: Between January 2002 June 2003, 1142 procedures were performed 113 (9.9 percent) received All patients cared for in microsurgical intensive care unit days. Through...
Extensive composite defects of the oromandibular area are usually created after surgical treatment T3 and T4 cancers, requiring complex reconstructive plastic procedures. The preferred method for this type defect is reconstruction with two free flaps. use vascularized fibula osteoseptocutaneous flap bone inner lining well known accepted. Among flaps that can be used outer soft-tissue reconstruction, most commonly have been forearm rectus abdominis myocutaneous flap. However, these some...
Free thin anterolateral thigh flaps combined with cervicoplasty were used in a series of seven patients undergoing reconstruction for previous burn injury from September 2000 to May 2001 at Chang Gung Memorial Hospital. This method uses suprafascial dissection technique provide flap improve cervical contour. Neck contractures had resulted flame burns six and chemical one patient. The mean age was 32.7 years (range, 22 45 years). size excised scar ranged 10 x 2 cm 26 5 (mean, 19.7 3.3 cm). 11...
Repairing full-thickness cheek defects involving the oral commissure in head and neck regions after tumor resection is a challenge for reconstructive surgeons. First, they are usually relatively large defects. Second, axes of intraoral lining different from each other. Third, shape volume defect sphincter should be considered individually. Lateral femoral circumflex perforator flaps with at least two independent cutaneous perforators suitable reconstruction such one stage. In this study,...
Massive defects of the head and neck regions after resection advanced carcinoma often require two flaps for optimal reconstruction. This study focuses on selection proper recipient vessels.A total 262 free-flap transfers were performed in 130 patients using two-flap approach (one patient received twice).For microvascular anastomosis inner (intraoral lining-bone reconstruction flaps), ipsilateral facial artery was used 56 (42.8 percent), superior thyroid 49 (37.4 a branch internal jugular...
Although postoperative radiotherapy has proved effective in improving local control and survival patients with head neck cancers, its complications, especially mandibular osteoradionecrosis, reduce the quality of life. Mandibular surgery before adds an additional risk factor for osteoradionecrosis. This study reviews Chang Gung Memorial Hospital, Taipei, Taiwan, over a 10-year period, who underwent intraoral cancer resection followed by thereafter developed osteoradionecrosis mandible. A...
Abstract Background Antioxidants have been shown to enhance the proliferation of adipose-derived mesenchymal stem cells (ADMSCs) in vitro , although detailed mechanism(s) and potential side effects are not fully understood. In this study, human ADMSCs cultured ImF-A medium supplemented with antioxidants ( N -acetyl- l -cysteine ascorbic acid-2-phosphate) fibroblast growth factor 2 (FGF-2) were compared FGF-2 alone (ImF) or under 5% pO conditions (ImF-H). Results During log-phase growth,...
chen m.-y., huang w.-c., peng y.-s., guo j.-s., c.-p., jong m.-c. & lin h.-c. (2011) Effectiveness of a health promotion programme for farmers and fishermen with type-2 diabetes in Taiwan. Journal Advanced Nursing 67(9), 2060–2067. Aims. This paper is report study examining the control foot self-care capability following introduction multi-stage, multi-disciplinary team community-based small group programme. Background. Improving critical issue Taiwan because mortality rates are increasing...
Head and neck tumors often require radiotherapy as part of the treatment protocol. Although it improves survival rate in cancer patients, may cause osteoradionecrosis, especially mandible maxilla. Twelve patients with osteoradionecrosis maxilla were treated microsurgical free tissue transplantations between April 1996 August 2002. There 10 male two female a mean age 60.2 years. The dose was 6674 cGy. radiation could not be traced three because performed elsewhere. Radical sequestrectomy,...
The pulmonary inflammatory response and dysfunction after cardiopulmonary bypass is a major problem in patients undergoing cardiac surgery. Propofol has anti-inflammatory immunomodulatory properties which may attenuate this response. Thirty were randomly assigned to receive saline (control group) or propofol (propofol group). Pulmonary thoracic compliance, respiratory index, malondialdehyde interleukin-8 concentrations intrapulmonary polymorphonucleocyte sequestration measured at pre-bypass...
Certain composite tissue allotransplants contain vascularized bone grafts (e.g., hand/forearm allotransplants). The authors investigated the role of graft within hind-limb osteomyocutaneous flap in inducing tolerance.Brown Norway and Lewis rats were used as allotransplant donors recipients, respectively. Experimental groups follows: group I, syngeneic controls (Lewis to Lewis); II, allogeneic (both received no pretransplantation total body irradiation); III, IV, V, which 5 mg antilymphocyte...
Mixed chimerism induces donor-specific tolerance to composite tissue allotransplants (CTAs). In the present studies, we used a nonmyeloablative conditioning approach establish and promote CTA acceptance.
Chen K-H, Lee K-F, Hsu H-C, Huang W-C, Hsiao K-Y, Fang K-M: The Role of High-Resolution Ultrasound in the Diagnosis a Traumatic Neuroma an Injured Median Nerve. Since development high-resolution ultrasound, its role diagnosis peripheral nerve lesions has steadily increased. We present case 42-yr-old woman who experienced consistent numbness over left hand and fingers after cutting wrist suicide attempt subsequent tendon median repair period rehabilitation. Electrodiagnostic testing was...
Background: The radial forearm flap has been a workhorse for soft-tissue or coverage reconstruction in the head and neck area. Although it several major advantages, requires sacrifice of artery. In this article, authors present their modification harvesting based on large septocutaneous branch artery proximal with without sacrificing main They name flap. Methods: From September 2003 to March 2004, total 14 free flaps were used 12 patients. There was one female patient 11 male Their ages...
Percutaneous radiofrequency trigeminal rhizotomy (RF-TR) is a well-established treatment for patients suffering from neuralgia (TN) as primary modality or those refractory to medical treatment. However, few existing studies have identified intraoperative parameter navigation technique that can be used predict the rates of short-term long-term pain relief. In this study, we analyzed patient characteristics, parameters and technical factors, postoperative changes in relation immediate...
<b>Introduction</b> Perforator flap transfer has the benefits of minimal donor site morbidity and customization in design. This study reports on proximal lateral leg perforator (PLLP) for head neck reconstruction. <b>Materials Methods</b> From January 2000 through December 2009, 18 patients underwent reconstruction with PLLP flap, including 16 males 2 females ranging age between 32 80 years old. The mean follow-up time was 9.8 months. <b>Results</b> Mother vessels flaps can arise 77.8%...
The brain-derived neurotrophic factor (BDNF) is vital in the neural differentiation of stem/progenitor cells, and together may have therapeutic potential for regeneration. In this study, a multiplexed polybutylcyanoacrylate nanoparticle (PBCA NP) delivery platform was constructed, incorporating either surface-adsorbed or encapsulated BDNF induction induced pleuripotent stem cells (iPSCs), where tween 80 (T80) superparamagnetic iron oxide (SPIO) were added central nervous system (CNS)...
Anterior cervical scar contracture remains a challenging problem for the plastic surgeon. Recent advances in flap techniques have made it possible to transfer various kinds of autogenous tissue. A free lateral leg perforator (LLPF) was first introduced and developed reconstruct this burn deformity, according special nature anatomy. The authors used resurface post-burn anterior 31-year-old female patient with second-to-third-degree flame burns. size excised 25 × 5.5 cm; 22 8 cm, total...
Previous studies demonstrated that both cyclosporine and tacrolimus in combination with antilymphocyte globulin could facilitate mixed chimerism induce tolerance to composite tissue allotransplants under partial myeloablative conditioning. The purpose of this study was compare the efficacy tacrolimus.Brown-Norway Lewis rats were used as allotransplant donors recipients, respectively. Cyclosporine groups I (n = 6), II 9), III 5) received subcutaneous injection 16 mg/kg (days 0 10);...