Alessandro Negri

ORCID: 0000-0002-7828-2947
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Research Areas
  • Body Contouring and Surgery
  • Extracellular vesicles in disease
  • Intracranial Aneurysms: Treatment and Complications
  • Dermatological and COVID-19 studies
  • Nanoparticle-Based Drug Delivery
  • Adipose Tissue and Metabolism
  • Textile materials and evaluations
  • Blood properties and coagulation
  • Hydrogels: synthesis, properties, applications
  • Tissue Engineering and Regenerative Medicine
  • Lower Extremity Biomechanics and Pathologies
  • Electrospun Nanofibers in Biomedical Applications
  • Characterization and Applications of Magnetic Nanoparticles
  • Nanoplatforms for cancer theranostics

University of Verona
2022-2025

This study investigates the theranostic potential of doped ferrite nanoparticles (NPs) with self-regulating temperature (SRT) properties, termed M55, coated glucose (GM55), chitosan (CM55), and poly-ethylene glycol (PM55). The NPs were assessed for their physicochemical attributes, magnetic fluid hyperthermia (MFH) efficacy, dual-imaging capabilities in Magnetic Resonance Imaging (MRI) Particle (MPI), cytocompatibility, cellular uptake. Physicochemical characterization was conducted using...

10.2147/ijn.s506443 article EN cc-by-nc International Journal of Nanomedicine 2025-03-01

The development of efficient and biocompatible contrast agents is particularly urgent for modern clinical surgery. Nanostructured materials raised great interest as different imaging techniques, which essential features are high contrasts, in the case precise surgery, minimization signal spatial dispersion when embedded biological tissues. This study deals with a multimodal agent based on an injectable hydrogel nanocomposite containing lanthanide-activated layered double hydroxide coupled to...

10.1021/acs.biomac.4c00312 article EN Biomacromolecules 2024-05-24

This paper reports a comprehensive investigation of magnetic nanoparticle (MNP), named M55, which belongs to class innovative doped ferrite nanomaterials, characterized by self-limiting temperature. M55 is obtained from M48, an MNP previously described our group, implementing additional purification step in the synthesis. after citrate and glucose coating, G-M55. The present study aimed demonstrate properties G-M55 as diagnostic contrast agent for MRI particle imaging (MPI), antitumoral...

10.3390/cancers14205150 article EN Cancers 2022-10-20

Abstract Background During the sexual maturation, gluteal femoral adipose tissue is subjected to numerous modifications, not observable in other regions, particular women and less men. Other authors described this region, but they used imaging techniques having lower resolution, than MRI proposed study. High resolution might provide important more detailed information about anatomy of region. Methods This study has been performed using 7 T‐magnetic resonance ultrastructural analysis order...

10.1111/jocd.16314 article EN cc-by Journal of Cosmetic Dermatology 2024-04-18

Dermal white adipose tissue (dWAT) in humans can be characterized as a relaxed dermal skin compartment consisting of functionally interlinked adipocytes. dWAT is typically discerned both terms morphology and function from subcutaneous (sWAT). In particular human thigh, the appears thin extensions panniculus to dermis, it primarily associated with pilosebaceous units, hair follicles, sebaceous glands, erector pili muscles. this work, fat samples obtained post-mortem gluteo-femoral region were...

10.1016/j.aanat.2024.152289 article EN cc-by Annals of Anatomy - Anatomischer Anzeiger 2024-06-06

Adipose tissue-derived adult stem (ADAS) cells and extracellular vesicle (EV) therapy offer promising avenues for treating neurodegenerative diseases due to their accessibility potential autologous cell transplantation. However, the clinical application of ADAS or EVs is limited by challenge precisely identifying them in specific regions interest. This study compares two superparamagnetic iron oxide nanoparticles, differing mainly size, determine efficacy allowing non-invasive tracking via...

10.3390/ijms25179701 article EN International Journal of Molecular Sciences 2024-09-07
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