Zhiwei Wang

ORCID: 0000-0002-7857-1837
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Research Areas
  • Cancer, Hypoxia, and Metabolism
  • Zebrafish Biomedical Research Applications
  • Autophagy in Disease and Therapy
  • Cellular Mechanics and Interactions
  • Endoplasmic Reticulum Stress and Disease
  • Angiogenesis and VEGF in Cancer

First Affiliated Hospital of Zhengzhou University
2022-2023

Abstract Background Diabetes-related limb ischemia is a challenge for lower extremity amputation. Aurora Kinase A (AURKA) an essential serine/threonine kinase mitosis, while its role in remains unclear. Method Human microvascular endothelial cells (HMEC-1) were cultured high glucose (HG, 25 mmol/L d -glucose) and no additional growth factors (ND) medium to mimic diabetes low deprivation as vitro model. Diabetic C57BL/6 mice induced by streptozotocin (STZ) administration. After seven days,...

10.1186/s10020-023-00635-4 article EN cc-by Molecular Medicine 2023-03-28
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