A5101494629- Peptidase Inhibition and Analysis
- Advanced Proteomics Techniques and Applications
- Endoplasmic Reticulum Stress and Disease
- Natural product bioactivities and synthesis
- Ubiquitin and proteasome pathways
- Enzyme function and inhibition
- Phytoestrogen effects and research
- Vibrio bacteria research studies
- Protein Hydrolysis and Bioactive Peptides
- Cancer, Lipids, and Metabolism
- Medical Imaging Techniques and Applications
- Legionella and Acanthamoeba research
- Polyamine Metabolism and Applications
- Metabolomics and Mass Spectrometry Studies
- Pancreatic and Hepatic Oncology Research
- Radiopharmaceutical Chemistry and Applications
Fujian Medical University
2019-2021
Mengchao Hepatobiliary Hospital
2019-2021
First Affiliated Hospital of Fujian Medical University
2019-2020
Wroclaw University of Environmental and Life Sciences
2010
Centers for Disease Control and Prevention
2007
Abstract Early detection and intervention are key strategies to reduce mortality, increase long-term survival, improve the therapeutic effects of hepatocellular carcinoma (HCC) patients. Herein, isobaric tag for relative absolute quantitation (iTRAQ)-based quantitative proteomic strategy was used study secretomes in conditioned media from HCC cancerous tissues, surrounding noncancerous distal tissues identify diagnostic prognostic biomarkers HCC. In total, 22 49 dysregulated secretory...
Hepatoma is one of the most common malignant tumor, and patients have very poor prognosis. Early prediction intervention hepatoma recurrence/metastasis are effective way to improve patients' clinical outcomes. Here, we used isobaric tags for relative absolute quantitation (iTRAQ) based quantitative phospho-proteomics approach identify biomarkers associated with in cell lines increasing metastasis ability. In total, 75 phosphorylated peptides corresponding 60 phosphoproteins were...
Abstract Early detection and intervention are key strategies to reduce mortality, increase long-term survival improve the therapeutic effects of hepatocellular carcinoma (HCC) patients. Herein, isobaric tag for relative absolute quantitation (iTRAQ) quantitative proteomic strategy was used study secretome in conditioned media from HCC cancerous tissues, surrounding noncancerous distal tissues identify diagnostic prognostic biomarkers HCC. In total, 22 49 secretory proteins were identified be...