A5038102249- Marine Bivalve and Aquaculture Studies
- Trace Elements in Health
- Marine Biology and Environmental Chemistry
- Heavy Metal Exposure and Toxicity
- Drug-Induced Hepatotoxicity and Protection
- Endoplasmic Reticulum Stress and Disease
- Marine Toxins and Detection Methods
- Bacterial biofilms and quorum sensing
- Aluminum toxicity and tolerance in plants and animals
- Bacteriophages and microbial interactions
- Bacterial Genetics and Biotechnology
- Marine Ecology and Invasive Species
- Arsenic contamination and mitigation
- Muscle Physiology and Disorders
- Environmental Toxicology and Ecotoxicology
- Liver Disease Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Nerve injury and regeneration
- Chemical synthesis and alkaloids
- Cholesterol and Lipid Metabolism
- Peroxisome Proliferator-Activated Receptors
- Axial and Atropisomeric Chirality Synthesis
- Genetic Neurodegenerative Diseases
First Affiliated Hospital of Anhui Medical University
2016-2023
Anhui Provincial Hospital
2022-2023
Anhui Medical University
2016-2023
Jinan University
2020-2021
South China Agricultural University
2021
Shanghai Jiao Tong University
2012
Previous study found that rifampicin caused intrahepatic cholestasis. This investigated the effects of on hepatic lipid metabolism. Mice were orally administered with (200 mg/kg) daily for different periods. Results showed serum TG level was progressively reduced after a short elevation. By contrast, content markedly increased in rifampicin-treated mice. An obvious accumulation, as determined by Oil Red O staining, observed mice treated more than one week. Moreover, mRNA levels Fas, Acc and...
Excessive acetaminophen (APAP) use can lead to acute liver injury (ALI) by inducing endoplasmic reticulum stress (ERS). We previously found that pretreatment with the peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand rosiglitazone (RSG) alleviated ALI in APAP-treated mice.To examine if RSG-mediated hepatoprotection is associated ERS suppression.Forty-eight male CD-1 mice were randomly divided into control, RSG, APAP 4 h, 24 RSG + and h groups. The groups received (20 mg/kg) gavage...
Abstract Microorganisms commonly use two-component systems (TCSs) to detect specific environmental changes and respond accordingly for their own benefit. However, the regulatory mechanisms physiological roles of a majority TCSs are still elusive. In this study, we focused on previously predicted TCS FleS/FleR in Pseudomonas aeruginosa systematically investigate its regulation roles. Loss fleS or fleR both genes led decreased biofilm formation attenuated motility PAO1, which could be restored...
Nerve injury commonly contributes to irreversible functional impairment, reconstruction of the function muscle is big challenge. In denervated skeletal muscle, therapid expression MyoD mRNA and protein also occurs during early postdenervation, which suggested that denervation-induced may be prevent atrophy. However, detail mechanism not clear. Therefore, in this study, we established a stable-transfected L6 cell line. After operation for cutting rats’ tibial nerve, MyoD-L6 cells were...