A5101793748- BRCA gene mutations in cancer
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Reproductive tract infections research
- Ethics in Clinical Research
- Genomics and Rare Diseases
- Adolescent Sexual and Reproductive Health
- Pharmaceutical industry and healthcare
- Urinary Tract Infections Management
- Ethics and Legal Issues in Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Genetic factors in colorectal cancer
- Focus Groups and Qualitative Methods
- Urinary and Genital Oncology Studies
- HIV, TB, and STIs Epidemiology
- Biotechnology and Related Fields
- Prenatal Screening and Diagnostics
- DNA Repair Mechanisms
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Biomedical Ethics and Regulation
- Autism Spectrum Disorder Research
- Nutrition, Genetics, and Disease
- Genetics and Neurodevelopmental Disorders
- Patient Satisfaction in Healthcare
- Genetic Syndromes and Imprinting
Cone Health
2013-2022
University of North Carolina at Greensboro
2009-2014
Birmingham Community Healthcare NHS Trust
2010-2012
The purpose of this study was to assess primary care physicians' awareness, experience, opinions and preparedness answer patients' questions regarding direct-to-consumer (DTC) genetic testing. An anonymous survey mailed 2,402 family internal medicine providers in North Carolina. Of the 382 respondents, 38.7% (n = 148) were aware 15% 59) felt prepared about DTC tests. Respondents aged 50 or older more likely be testing than those less 40 years old (OR 2.42). Male feel female 2.65). Among...
Introduction: Family health history is a strong predictor of disease risk. To reduce the morbidity and mortality many chronic diseases, risk-stratified evidence-based guidelines strongly encourage collection synthesis family to guide selection primary prevention strategies. However, such information not well integrated into clinical practice. address barriers use histories, Genomedical Connection developed validated MeTree, Web-based, patient-facing decision support tool. MeTree designed for...
Family health history (FHH) is the single strongest predictor of disease risk and yet significantly underutilized in primary care. We developed a patient facing FHH collection tool, MeTree©, that uses stratification to generate clinical decision support for breast cancer, colorectal ovarian hereditary cancer syndromes, thrombosis. Here we present data on experience patients providers after integration MeTree© into 2 care practices. This was Type hybrid controlled implementation-effectiveness...
The CDC's Family History Public Health Initiative encourages adoption and increase awareness of family health history. To meet these goals develop a personalized medicine implementation science research agenda, the Genomedical Connection is using an (T3 research) framework to integrate self-administered computerized history system with built-in decision support into 2 primary care clinics in North Carolina. collects three generation on 48 conditions provides (pedigree tabular history,...
To assess the educational needs of North Carolina primary care physicians (PCPs) about direct-to-consumer (DTC) genetic testing, surveys were mailed to 2,402 family and internal medicine providers in Carolina. Out 382 respondents, 323 (85%) felt unprepared answer patient questions 282 (74%) reported wanting learn DTC testing. A total 148 (39%) aware Among these, 63 (43%) thought testing was clinically useful. PCPs who either (OR = 0.354, p 0.01) or that useful 5.783, 0.00) more likely want...
Studies have shown that the quality of family health history (FHH) collection in primary care is inadequate to assess disease risk. To use FHH for risk assessment, collected data must adequate detail. address this issue, we developed a patient facing assessment tool, MeTree. In paper report content and using Design: A hybrid implementation-effectiveness study. Patients were recruited from 2009 2012. Setting: Two community clinics Greensboro, NC. Participants: All non-adopted adult English...
The Genomic Medicine Model aims to facilitate patient engagement, patient/provider education of genomics/personalized medicine, and uptake risk‐stratified evidence‐based prevention guidelines using MeTree, a patient‐facing family health history (FHH) collection clinical decision support (CDS) program. Here we report the number increased risk (above population‐level risk) patients identified for breast/ovarian cancer, colon hereditary syndrome risk, thrombosis; prevalence FHH elements...
Family health history can predict a patient's risk for common complex diseases. This project assessed the completeness of family data in medical charts and evaluated utility these performing assessments primary care.Family were collected analyzed to determine presence quality indicators that are necessary effective accurate assessment disease risk.More than 99% 390 paper contained information about history, which was usually scattered throughout chart. Information on parents more often other...
Abstract Primary care providers (PCPs) offered input regarding the incorporation of a family health history (FHH) risk assessment tool into community system (CHCS). Sixteen PCPs participated in one three focus groups. Perceived impediments included lack standard screening guidelines, effective tests, genetic counseling resources, and services for high‐risk patients. The were concerned about their level expertise, cost preventive care, discrimination. They also use FHH by oncologists within...
Abstract Several barriers inhibit collection and use of detailed family health history (FHH) in primary care. MeTree, a computer‐based FHH intake risk assessment tool with clinical decision support, was developed to overcome these barriers. Here, we describe the impact MeTree on genetic counseling (GC) referrals attendance. Non‐adopted, English speaking adults scheduled for well‐visit two community‐based primary‐care clinics were invited participate an Implementation‐Effectiveness study...
<i>Background:</i> Focus groups were conducted in a mid-sized community to explore members’ awareness and perceptions of genomic medicine identify effective methods educate the public about this topic. <i>Methods:</i> Thirteen focus with demographically representative pool 121 participants using semi-structured interview guide. Transcripts analyzed through computer assisted approach Atlas TI consisting coding, categorizing, comparing, contrasting relevant data....
According to the 2008 National Society of Genetic Counselors (NSGC) Professional Status Survey (PSS), 31 genetic counselor respondents reported spending at least 50% their time in area public health. The NSGC Public Health Special Interest Group (PHSIG) had 49 dues-paying members 2009. purpose this study was identify work settings and health activities which counselors participate. A novel online survey disseminated over PHSIG Listserv. Forty-one percent (n = 13) worked a university medical...
Specialization within genetic counseling is apparent, with 29 primary specialties listed in the National Society of Genetic Counselors' 2012 Professional Status Survey (PSS). PSS results show a steady proportion counselors primarily involved public health, yet do not identify all those performing health activities. Little known about skills needed to perform activities outside "traditional" counselor roles and expertise execute skills. This study aimed engaging activities, used, most...
Vulvovaginal candidiasis, or vaginal thrush, is a common yeast infection experienced by three out of four women at some point in their lives. Females who experience recurrent symptoms thrush may resort to buying products over-the-counter and will often fail seek professional help. The can impact greatly on the quality life woman, lead depression sexual problems with partners.
Bacterial vaginosis is experienced by 10 per cent of women and a common cause acute vaginitis.
Abstract Background: The Does It Run In Family? booklets provide educational materials about family health history (FHH) and basic genetics to readers of all levels are customizable for local communities. Purpose: were customized provided focus groups evaluate their usefulness in conveying information at a low reading level. Methods: Three with 19 participants reviewed the booklets. A semi-structured group guide was used. Transcripts analyzed manually coded themes. Results: Five themes...
Objectives Do weekly prophylactic saline or acidic catheter washouts in addition to standard long-term (LTC) care improve the outcomes of adults with LTC compared only. Design Three-arm superiority open-label randomised controlled trial. Setting UK community-based study. Participants 80 (any type/route) ≥28 days situ no plans discontinue and able self-manage washouts/study documentation with/without a carer. Interventions Randomly allocated (26:27:27) receive for up 24 months. Primary...
Individuals with Prader-Willi syndrome (PWS) have several common findings that may predispose to ingestion of potentially dangerous items. This study examined whether individuals PWS an increased prevalence toxic ingestions. A survey regarding history ingestions in and sibling controls was designed, piloted, distributed on-line. The subjects were (N = 129). subjects' non-PWS siblings served as 134). Participants who completed the anonymous online either parents or primary caretaker PWS....
Genetic testing is an instrumental tool used to determine whether individual has a predisposition certain cancers. Knowing of hereditary cancer may allow patient and their family consider high-risk screening or risk-reducing options. counselors work with physicians identify patients at increased risk for genetic using available guidelines such as those provided by the National Comprehensive Cancer Network (NCCN). Information within one hospital system's registry was individuals who qualify...