A5029266917- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Bone health and treatments
- Advanced Radiotherapy Techniques
- Pharmacological Effects and Toxicity Studies
- Drug Transport and Resistance Mechanisms
- Ion Transport and Channel Regulation
- Dermatological and Skeletal Disorders
- Contact Dermatitis and Allergies
- Mechanisms of cancer metastasis
- Additive Manufacturing and 3D Printing Technologies
- Autoimmune Bullous Skin Diseases
- Neuroblastoma Research and Treatments
- Cancer Cells and Metastasis
- Inflammatory Myopathies and Dermatomyositis
- Neuroendocrine Tumor Research Advances
- Bone Tissue Engineering Materials
- Cancer, Hypoxia, and Metabolism
- PI3K/AKT/mTOR signaling in cancer
- Ovarian cancer diagnosis and treatment
- Orthopaedic implants and arthroplasty
- Lung Cancer Research Studies
- Spine and Intervertebral Disc Pathology
- Sarcoma Diagnosis and Treatment
- Testicular diseases and treatments
Marshall University
2022-2024
Translational Genomics Research Institute
2022
Limited data are currently available on clinical outcomes after stereotactic body radiation therapy (SBRT) for pediatric and adolescent young adult (AYA) patients with cancer. We aimed to perform a systematic review study-level meta-analysis characterize associated local control (LC), progression-free survival (PFS), overall survival, toxicity SBRT.
The repair of orthopedic and maxillofacial defects in modern medicine currently relies heavily on the use autograft, allograft, void fillers, or other structural material composites. This study examines vitro osteo regenerative potential polycaprolactone (PCL) tissue scaffolding, fabricated via a three-dimensional (3D) additive manufacturing technology, i.e., pneumatic micro extrusion (PME) process. objectives this were: (i) To examine innate osteoinductive osteoconductive 3D-printed PCL...
The mechanistic target of rapamycin (mTOR) kinase is a component two signaling complexes that are known as mTOR complex 1 (mTORC1) and mTORC2. We sought to identify mTOR-phosphorylated proteins differently expressed in clinically resected clear cell renal carcinoma (ccRCC) relative pair-matched normal tissue. Using proteomic array, we found N-Myc Downstream Regulated (NDRG1) showed the greatest increase (3.3-fold) phosphorylation (on Thr346) ccRCC. This was associated with an total NDRG1....
The objective of this study was to compare clinical outcomes following single fraction versus fractionated stereotactic body radiotherapy (SBRT) for spinal metastases.A multi-institutional registry queried patients with metastases treated single-fraction or SBRT. Potential predictive factors local control (LC) and overall survival were evaluated. Pretreatment posttreatment Visual Analog Scale scores analyzed examine initial durable pain responses complete response (CR) rates. Logistic...
Glioblastomas (GBMs) are a form of malignant gliomas characterized by dismal prognosis. Standard treatment for glioblastoma patients is combined maximal surgical removal the tumor with postoperative radiotherapy and concomitant chemotherapy Temozolomide (TMZ). Among histological characteristics that contribute to GBM progression rapid proliferation neo-angiogenetic processes. The Na+/K+-ATPase transporter promotes migration cancer cells, its aberrant expression activity have been associated...
e17584 Background: Disease recurrence and progression of ovarian cancer is a common event, which accompanied by the development platinum-resistant or refractory disease. The presence chemo-resistant stem cells (CSCs) contributes to tumor propagation, maintenance, treatment resistance this difficult treat choice appropriate chemotherapy critical management advanced epithelial cancer. We developed CSCs assay (ChemoID) that identifies most effective for individual patients from panel...
e20507 Background: Pulmonary typical carcinoid tumors(TC) are rare and the treatment of these tumors has not been well studied. The purpose our investigation is to find whether or increasing in frequency assess value different options. Methods: National Cancer Database was queried from years 2004-2015 for those patients who underwent a surgical resection((bi)lobectomy(L+) sub-lobar resection(L-)) TC. Multi-variate analysis overall survival (OS) used propensity matching determine benefits...
Symmetrical drug-related intertriginous and flexural exanthema (also known as Baboon syndrome) is a skin eruption in the areas. It believed to be delayed-type hypersensitivity response drug which occurs secondary systemic absorption of agents after cutaneous sensitization. Our case provides high quality clinical images aid diagnosis this uncommon eruption.