A5047519697- Mesenchymal stem cell research
- Osteoarthritis Treatment and Mechanisms
- Cardiac Ischemia and Reperfusion
- Periodontal Regeneration and Treatments
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- T-cell and B-cell Immunology
- Cancer, Hypoxia, and Metabolism
- Cancer-related molecular mechanisms research
- biodegradable polymer synthesis and properties
- Bone health and treatments
- Cardiac Fibrosis and Remodeling
- CAR-T cell therapy research
- Bone fractures and treatments
- Adipose Tissue and Metabolism
- Cardiac Structural Anomalies and Repair
- Congenital heart defects research
Université de Montpellier
2021-2024
Laboratoire d'études sur les monothéismes
2024
Hôpital Saint Eloi
2024
Inserm
2021-2024
Institute for Regenerative Medicine & Biotherapy
2019-2022
Mesenchymal Stromal Cells (MSC) have been widely used for their therapeutic properties in many clinical applications including myocardial infarction. Despite promising preclinical results and evidences of safety efficacy phases I/ II, inconsistencies phase III trials reported. In a previous study, we shown using MSC derived from the bone marrow PPARβ/δ (Peroxisome proliferator-activated receptors β/δ) knockout mice that acute cardioprotective during first hour reperfusion are...
Initially discovered for its ability to regenerate ear holes, the Murphy Roth Large (MRL) mouse has been subject of multiple research studies aimed at evaluating other body tissues and deciphering mechanisms underlying it. These enhanced abilities regenerate, retained during adulthood, protect MRL from degenerative diseases such as osteoarthritis (OA). Here, we hypothesized that mesenchymal stromal/stem cells (MSC) derived regenerative could be involved in their potential through release...
Objective: Cartilage, as the majority of adult mammalian tissues, has limited regeneration capacity. Cartilage degradation consecutive to joint injury or aging then leads irreversible damage and diseases. In contrast, several vertebrate species such zebrafish have remarkable capacity spontaneously regenerate skeletal structures after severe injuries. The objective our study was test regenerative Meckel’s cartilage (MC) upon mechanical in identify mechanisms underlying this process. Methods...
Abstract Background: Initially discovered for its ability to regenerate ear holes, the MRL mouse has been subject of multiple research studies aimed at evaluating other body tissues and deciphering mechanisms underlying it. These enhanced abilities regenerate, retained in adult, protect from degenerative diseases such as osteoarthritis (OA). Here, we hypothesized that MSC derived regenerative could be involved their potential through release pro-regenerative mediators. Method: To address...
Abstract Background Initially discovered for its ability to regenerate ear holes, the MRL mouse has been subject of multiple research studies aimed at evaluating other body tissues and deciphering mechanisms underlying it. These enhanced abilities regenerate, retained in adult, protect from degenerative diseases such as osteoarthritis (OA). Here, we hypothesized that MSC derived regenerative could be involved their potential through release pro-regenerative mediators. Method To address this...
Abstract Background: Mesenchymal Stromal Cells (MSC) have been widely used for their therapeutic properties in many clinical applications including myocardial infarction. Despite promising preclinical results and evidences of safety efficacy phases I/ II, inconsistencies phase III trials reported. In a previous study, we shown using MSC derived from the bone marrow PPARβ/δ (Peroxisome proliferator-activated receptors β/δ) knockout mice that acute cardioprotective during first hour...