- Kidney Stones and Urolithiasis Treatments
- Cancer-related molecular mechanisms research
- TGF-β signaling in diseases
- Acute Kidney Injury Research
- Cancer-related gene regulation
- Advanced Neuroimaging Techniques and Applications
- Urologic and reproductive health conditions
- Renal Transplantation Outcomes and Treatments
- Cancer-related Molecular Pathways
- HIV Research and Treatment
- RNA modifications and cancer
- Cytomegalovirus and herpesvirus research
- Hippo pathway signaling and YAP/TAZ
- Cell death mechanisms and regulation
- Heme Oxygenase-1 and Carbon Monoxide
- Circular RNAs in diseases
- Cell Adhesion Molecules Research
- Ginseng Biological Effects and Applications
- Organ Transplantation Techniques and Outcomes
- Urinary Bladder and Prostate Research
- Fetal and Pediatric Neurological Disorders
- Medicinal plant effects and applications
- Orthopedic Infections and Treatments
- Urinary and Genital Oncology Studies
- Neonatal Health and Biochemistry
Peking University
2022
Peking University People's Hospital
2022
Nantong University
2015-2021
Taizhou People's Hospital
2015-2021
Beijing University of Chinese Medicine
2019
Shanghai University
2014
Sichuan University
2006
Ginsenoside Rh2 (GRh2) has been reported to have therapeutic effects on some types of cancer, but its effect prostatic cancer not extensively evaluated. Here, we show that GRh2 can substantially inhibit the growth in vivo and vitro. Moreover, inhibition tumor appeared result from a combined inhibitory cell proliferation invasiveness. Further analyses suggest seemed activate transforming factor β (TGFβ) receptor signaling cells, which subsequently inhibits invasion through regulating...
The role of yes-associated protein (YAP) in human prostate cancer DU145 cells and its underlying molecular mechanisms were explored the present study. Initially, expression levels YAP detected cells, which revealed that was highly expressed these cells. To investigate a stable YAP‑silenced cell line generated using YAP‑small interfering RNA. Reverse transcription‑quantitative polymerase chain reaction western blotting performed for mRNA detection, respectively. An MTT assay flow cytometry to...
Expression of microRNA(miR)-142-3p has been implicated to be associated with several cancers, whereas its function in bladder cancer (BC) remains unknown. The present study aimed explore the correlation between expression miR-142-3p and proliferation, migration invasion cells by activating Rac1. qRT-PCR was used measure miR-142- 3p tissues cell lines. RNA transfection silence accelerate cells. CCK-8 trans-well assays were detect before after transfection. direct interaction Rac1 demonstrated...
The aim of the present study was to explore association between parameters diffusion tensor imaging (DTI), including fractional anisotropy (FA) values, apparent coefficient (ADC) values and tractography (DTT) map, with Gleason score prostate cancer (PCa). A retrospective 50 cases PCa confirmed by biopsy or surgical pathology performed. Conventional magnetic resonance DTI scans were conducted in these cases. divided into three groups, low, intermediate high grade, according score. Post-DTI...
To explore the effects of cinobufagin (CBF), an active component toad venom (Bufo bufo gargarizans CANTOR), on proliferation and apoptosis PC3 human prostate cancer cells in vitro preliminarily investigate mechanism CBF suppressing tumor cell growth vivo. The effect was detected using MTT assay. morphological changes were observed under optical microscope. Colony formation assays used to observe colony by cells. after treatment with for 48 hours monitored flow cytometry. Furthermore,...
Abstract We present here the three-dimensional (3D) visualization fused with ultrasound and to evaluate its clinical application effect preliminarily. One hundred eighteen patients renal calculi in our hospital from September 2017 December 2019 were prospectively randomized into two groups. The experimental group was treated percutaneous puncture guided by 3D ultrasound. control B-ultrasonography (B-US). time versus 4.36 ± 1.28 min 10.72 2.94 ( P = 0.000), operation 65.85 10.63 81.34 12.52...
Abstract We present here the three-dimensional (3D) visualization fused with ultrasound and to evaluate its clinical application effect preliminarily. One hundred eighteen patients renal calculi in our hospital from September 2017 December 2019 were prospectively randomized into two groups. The experimental group was treated percutaneous puncture guided by 3D ultrasound. control B-ultrasonography (B-US). time, operation loss of hemoglobin lower than those group, success rate establishing...
Background: Reconstruction after en bloc resection of the distal tibia has remained an unsettled issue despite many attempts with bone grafts or prostheses in past. Failures previous methods have been attributed to inadequate mechanical strength, poor articular stability, failed osseointegration, and soft tissue coverage. To overcome these shortcomings, we designed applied a 3D-printed megaprosthesis ankle arthrodesis. Methods: A total 13 patients underwent tibial tumor reconstruction...
Objective To investigate the pathological and immunohistochemical characteristics of female bladder ectopic skene glands. Methods A with tumor was treated in our hospital May 2013. Preoperative sonography revealed a 0.9 cm×0.6 cm round solid mass bottom wall. Mass hypoechoic homogeneous regular shape, blood flow within noted. The transurethral resection. Routine examination suggested Skene glands. Immunohistochemical stains for prostate specific antigen (PSA), spectific acid...