A5089111319- Gut microbiota and health
- GABA and Rice Research
- Probiotics and Fermented Foods
- Food composition and properties
- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Liver Disease Diagnosis and Treatment
- Tea Polyphenols and Effects
- Proteins in Food Systems
- Genetic Neurodegenerative Diseases
- Phytoestrogen effects and research
- Pancreatitis Pathology and Treatment
- Antioxidants, Aging, Portulaca oleracea
- Adipose Tissue and Metabolism
- Hydrogen's biological and therapeutic effects
- Mitochondrial Function and Pathology
- Metabolomics and Mass Spectrometry Studies
- Medicinal Plants and Bioactive Compounds
- Nutritional Studies and Diet
Johns Hopkins Medicine
2025
Johns Hopkins University
2025
Shihezi University
2024-2025
Ministry of Agriculture and Rural Affairs
2025
Tianjin University of Science and Technology
2019-2024
The influence of phenolic compound extracts from three colored rice cultivars on the gut microbiota was investigated. results revealed that protocatechuic acid, chlorogenic caffeic acid and p-coumaric were major metabolites after fermentation. presence compounds led to a significantly decreased ratio Firmicutes Bacteroidetes, while abundance Proteobacteria decreased. At genus level, promoted an increase Prevotella, Megamonas Bifidobacterium, Bacteroides Escherichia-Shigella inhibited....
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by CAG-repeat expansion in exon-1 of the huntingtin gene. Currently, no disease-modifying therapies are available, with significant challenge evaluating therapeutic efficacy before clinical symptoms emerge. This highlights need for early biomarkers and intervention strategies. Therefore, it essential to develop characterize accurate mouse models identify preclinical development. In this study, we characterized...
This study investigated effects of triterpenoids derived from Ganoderma lucidum (GLT) on the ability to attenuate cognitive impairment and reduce oxidative stress inflammation induced by D-galactose using an aged rats model. The data revealed that dietary GLT intervention improved memory in a water maze experiment. A reduction was also achieved as decreased levels MDA, AGEs, NO, TNF-α AChE activity, increased activity T-AOC, GSH-Px, T-SOD, CAT IL-2 level serum. revised hepatocyte cellular...
The current study applied an ob/ob mouse model of obesity for investigating the impact different RS doses in a high-fat (HF) diet on attenuation metabolic syndrome. Although significant reduction body weight was not achieved, intervention significantly decreased liver with suppressed lipid accumulation tissue and reduced adipocyte size fat tissue. All levels were associated enriched pathways PPAR, NAFLD cGMP-PKG signaling. In contrast, either medium or higher intake (MRS HRS, respectively)...
Considering that the study on impact of long-term consumption resistant starch metabolic syndromes induced by a high-fat diet (HFD) is rare, this investigation designed 36-week HFD containing three RS levels (LRS, MRS, and HRS) for measuring changes in serum parameters, liver transcriptome, gut microbiota. Results indicated all significantly reduced food intakes body gain, followed increased leptin PYY, but did not show dose-dependence. Furthermore, MRS triggered greater number enriched...