A5035086598- Diet and metabolism studies
- Diabetes and associated disorders
- Diabetes Management and Research
- Obesity, Physical Activity, Diet
- LGBTQ Health, Identity, and Policy
- Venous Thromboembolism Diagnosis and Management
- Eating Disorders and Behaviors
- Neonatal Health and Biochemistry
- Diabetes Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Epigenetics and DNA Methylation
- Pediatric Urology and Nephrology Studies
- Adipose Tissue and Metabolism
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Autism Spectrum Disorder Research
- Chronic Disease Management Strategies
- Hormonal and reproductive studies
- Ethics and Legal Issues in Pediatric Healthcare
- Birth, Development, and Health
- Systemic Sclerosis and Related Diseases
- Peripheral Artery Disease Management
- Reproductive Health and Technologies
- Hip and Femur Fractures
- Dietary Effects on Health
- Bariatric Surgery and Outcomes
Harvard University
2020-2024
Boston Children's Hospital
2017-2024
Massachusetts General Hospital
2017-2021
Boston Children's Museum
2021
Joslin Diabetes Center
2014
Abstract Context Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by endocrine and neuropsychiatric problems including hyperphagia, anxiousness, distress. Intranasal carbetocin, an oxytocin analog, was investigated as selective replacement therapy. Objective To evaluate safety efficacy of intranasal carbetocin in PWS. Design Randomized, double-blind, placebo-controlled phase 3 trial with long-term follow-up. Setting Twenty-four ambulatory clinics at academic medical...
Youth with type 1 diabetes (T1D) are at risk for weight gain due to the epidemic of childhood overweight/obesity and common use intensive insulin therapy; latter resulted in Diabetes Control Complications Trial.To assess prevalence therapy youth T1D over a decade identify factors associated status glycemic control.We obtained cross-sectional data from four unique cohorts (1999, 2002, 2006, 2009). (N = 507, 49% male) were 8-16 yr old duration ≥6 months, A1c 6.0-12.0% (42-108 mmol/mol), daily...
Transgender and gender-diverse (TGD) youth experience barriers to accessing health care are at risk for poorer overall compared with cisgender peers. In the last year, dozens of US legislative bills have been proposed restrict rights TGD youth.1 A subset these aims access essential treatment diagnosed gender dysphoria, even when they meet rigorous criteria, as determined by a multidisciplinary evaluation (Table 1).1,2 Other legislation would criminalize clinicians who provide...
Summary Data are conflicting regarding the impact of weight loss on mood and anxiety in adolescent young adult females with moderate to severe obesity (OB), who at increased risk for dysfunction compared normal‐weight (NW). We examined depressive symptoms 94 13‐21 years old: 39 NW group (body mass index [BMI]: 5 th ‐85 percentiles) 55 OB (BMI >40 kg/m 2 or >35 comorbidities). Fifteen participants underwent bariatric surgery (gastric bypass sleeve gastrectomy) 15 getting routine care...
Abstract Background The risk of venous thromboembolism (VTE) with gender‐affirming hormone therapy (GAHT) in transgender and gender non‐binary (TNB) youth is unclear. Objective To identify the rate VTE a cohort TNB followed health clinic at Boston Children's Hospital, to investigate impact congenital thrombophilia diagnosis on use GAHT. Methods ICD‐9 ICD‐10 codes were used eligible individuals, defined as (i) having dysphoria (ii) (VTE). Data abstracted from review medical records. A second...
Background: Education and management for new onset diabetes (NOD) does not always require hospitalization. A pathway outpatient of pediatric NOD patients after initial evaluation long-acting insulin dose in the emergency department was developed at a tertiary academic medical center. Methods: multidisciplinary team identified key eligibility criteria including absence DKA, age ≥3 years, beta-hydroxybutyrate (BOHB) <1 mmol/L. Data tracking, chart review, endocrine provider surveys...
A 13-month-old white boy presents to the emergency department (ED) with sudden onset of abdominal discomfort and lethargy. There is no history fevers, vomiting, or diarrhea. He was born at 39 weeks’ gestation by spontaneous vaginal delivery. has had surgery, he does not take any medications. His immunizations are up date developmentally appropriate. Some older family members have gastric, uterine, cervical cancers. Physical examination reveals a crying but consolable child. afebrile heart...