A5078805145- Dermatology and Skin Diseases
- Immunodeficiency and Autoimmune Disorders
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Blood disorders and treatments
- Gut microbiota and health
- Congenital heart defects research
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Allergic Rhinitis and Sensitization
- Hepatitis B Virus Studies
- Renal Diseases and Glomerulopathies
- Tryptophan and brain disorders
- Pharmaceutical studies and practices
- Protein Tyrosine Phosphatases
- Cutaneous lymphoproliferative disorders research
- Genomic variations and chromosomal abnormalities
- Neurogenetic and Muscular Disorders Research
- Nail Diseases and Treatments
- Infant Health and Development
- Genomics and Rare Diseases
- Vasculitis and related conditions
- Pneumocystis jirovecii pneumonia detection and treatment
- Genetic and rare skin diseases.
- Cutaneous Melanoma Detection and Management
Shanghai Children's Medical Center
2008-2024
Shanghai Jiao Tong University
2011-2024
Abstract Background Atopic dermatitis (AD) often arises in infancy, and gut microbial dysbiosis is associated with the development of AD. However, less known about specific changes early‐life microbiome AD severity. This study aims to reveal composition function profiles severity infants. Methods Sixty‐two infants (mean [SD] age, 4.7[1.9] months) different severities were enrolled divided into three groups (mild, moderate severe) according Scoring Dermatitis (SCORAD) index. The analysed by...
To cite this article: Jin Y‐Y, Cao R‐M, Chen J, Kaku Y, Wu Cheng Shimizu T, Takase M, S‐M, T‐X. Partially hydrolyzed cow’s milk formula has a therapeutic effect on the infants with mild to moderate atopic dermatitis: randomized, double‐blind study. Pediatric Allergy Immunology 2011; 22 : 688–694. Abstract Objective: The allergy‐preventing of partially (phCMF) in at high risk dermatitis (AD) been demonstrated many studies. However, potential phCMF treating AD not reported. We sought assess...
Background: Wiskott-Aldrich syndrome (WAS) is a rare and severe X-linked disorder with variable clinical phenotypes correlating the type of mutations in WAS gene. The difficult to differentiate from idiopathic thrombocytopenic purpura (ITP) before genetic diagnosis. We retrospectively reviewed patients suspected have who were referred our hospital 2004 2016 compared features laboratory examination genetically confirmed diagnosed ITP order seek some clues distinguish Methods: Seventy-eight...
Chromosome 1p36 deletion is the most common subtelomeric syndrome characterized by variable features including unique facial appearance, intellectual disability, developmental delay, cardiac defects, seizures and hypotonia. Here, we report a patient with dilated cardiomyopathy, seizures, hirsutism cutis laxa who was diagnosed chromosome microarray analysis. This first reported case of associated our results suggest that region contains one or more genes relevant to laxa. also indicates...
Abstract Bacille Calmette‐Guérin (BCG), a live attenuated vaccine prepared using Mycobacterium bovis , can prevent tuberculosis in children and is routinely administered to infants China many other countries. A serious complication following vaccination disseminated BCG infection. The risk greatly increased patients with severe combined immunodeficiency disease (SCID), syndrome characterized by deficiency of both humoral cellular immunity. We report case infection an infant SCID caused two...
Abstract The diagnosis of food allergy in clinical practice has not been standardized, and is overdiagnosed patients with atopic dermatitis (AD). This overdiagnosis leads to unnecessary elimination diets that may exert potential adverse effects on the health children AD. Unlike classic IgE-mediated allergy, AD manifest as non-eczematous reactions, isolated eczematous or a combination these reactions. should be made based thorough history (detailed allergic feeding history), manifestations,...
BACKGROUND The presence of scalp nevi in children frequently causes apprehension, leading physicians and parents to consider unnecessary biopsies or excisions children. There are limited data on the dermoscopic characteristics Chinese OBJECTIVE aim this study was comprehensively analyze clinical features specific population pediatric patients, with a focus single dermatologic surgery practice. METHODS This retrospective cohort investigated patients who underwent surgical excision nevi. All...
<title>Abstract</title> <bold>Background: </bold>Atopic dermatitis (AD) often arises in infancy, and gut microbial dysbiosis is associated with the development of AD. However, less known about specific changes early-life microbiome AD severity. This study aims to reveal composition function profiles severity infants. <bold>Methods: </bold>Sixty-two infants (mean [SD] age, 4.7[1.9] months) different severities were enrolled divided into three groups (mild, moderate, severe) according Scoring...
Background: Mutations in LPS-responsive and beige-like anchor (LRBA) gene patients were firstly described to associate with a syndrome of immune deficiency autoimmunity 2012. However, there was still no LRBA deficient patient reported China. Objectives: We present Chinese heterozygous mutations his clinical, immunological genetic features. Methods: Patient's clinical data collected analyzed. Laboratory results included lymphocyte subsets analysis immunoglobulin quantification. Targeted...