A5100667631- Drug-Induced Hepatotoxicity and Protection
- Pharmacological Effects of Natural Compounds
- Advanced Neuroimaging Techniques and Applications
- Prenatal Screening and Diagnostics
- Functional Brain Connectivity Studies
- Retinal Diseases and Treatments
- Fungal Biology and Applications
- Schizophrenia research and treatment
- Nanoparticles: synthesis and applications
- Retinal Imaging and Analysis
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Gut microbiota and health
- Drug Transport and Resistance Mechanisms
- Glaucoma and retinal disorders
- Parvovirus B19 Infection Studies
- Biological and pharmacological studies of plants
- Moringa oleifera research and applications
- Polysaccharides and Plant Cell Walls
- Congenital Anomalies and Fetal Surgery
- Ginger and Zingiberaceae research
- Liver Disease Diagnosis and Treatment
- Tryptophan and brain disorders
- Bone Tissue Engineering Materials
Gannan Medical University
2023-2024
Guiyang Medical University
2021-2024
Northwest University
2024
Affiliated Hospital of Guizhou Medical University
2021-2024
Shanghai Jiao Tong University
2019-2024
Shanghai Children's Medical Center
2024
Qingdao University
2021-2022
Affiliated Hospital of Qingdao University
2021-2022
Hebei Medical University
2022
Dazhou Central Hospital
2022
Background and Purpose Acetaminophen‐induced acute liver injury (AILI) is the most frequent cause of failure in developed countries. Given significant limitations associated with N‐acetyl cysteine, only antidote used to treat AILI, development novel therapeutic approaches that can offer a wide range time‐windows clearly needed. Glycycoumarin (GCM), natural coumarin purified from liquorice, has been previously demonstrated possess potent hepatoprotective effects. In present study, we aimed...
Grifola frondosa is an edible medicinal mushroom that has been proven to have a variety of health benefits. The main active ingredients this are polysaccharides. In study, ultrasonic-assisted extraction was used obtain crude polysaccharides (GFPs). Then, purified GFP obtained after purification. optimum conditions were time 71 min, temperature 90°C in solid-to-liquid ratio 1:37 g/mL, and ultrasonic power 500 W. using DEAE-52 Sephadex G-100. structural characterization performed Fourier...
Purpose A number of studies have shown that the levels some proteins in aqueous humor (AH) are altered and correlate with mechanisms or prognosis many eye diseases. To identify possible lead to development wet age‐related macular degeneration (AMD), a proteomic analysis AH composition from AMD patients was performed compared non‐AMD cataract patients. Experimental design Six six were enrolled. approach which included two‐dimensional electrophoresis coupled MS bioinformatics methods used...
Abstract Background Atopic dermatitis (AD) often arises in infancy, and gut microbial dysbiosis is associated with the development of AD. However, less known about specific changes early‐life microbiome AD severity. This study aims to reveal composition function profiles severity infants. Methods Sixty‐two infants (mean [SD] age, 4.7[1.9] months) different severities were enrolled divided into three groups (mild, moderate severe) according Scoring Dermatitis (SCORAD) index. The analysed by...
Dendrobium officinale flos (DOF), a novel food raw material, is used in Chinese folk medicine to nourish the stomach. However, there still no available study evaluate effects of DOF on animal models acute gastric injury and its mechanism by modern pharmacological research.
Background . Ganoderma lucidum polysaccharides (GLP) has anti-inflammatory and immunomodulatory effects. Dysregulated immune responses are involved in the pathogenesis of dextran sulfate sodium (DSS)-induced colitis. The aim this study was to assess therapeutic potential GLP alleviate DSS-induced Methods mice were administered with by intragastric gavage daily for two weeks prior DSS treatment. Mice orally 2.5% dissolved drinking water or treatment 6 days. killed on day 7 after induction...
The mechanisms responsible for macular edema with branch retinal vein occlusion (BRVO) remain to be elucidated. It is known that the expression profile of certain proteins in aqueous humor (AH) changes some diseases. Accordingly, determining these AH may aid understanding their potential role this pathogenesis. aim study was identify possible involved development BRVO-induced edema. A proteomic analysis composition eyes patients BRVO performed and compared cataract (non-BRVO; controls). from...
This study was aimed to explore the mechanism of Aconiti Lateralis Radix Praeparata (ALRP) and Zingiberis Rhizoma (ZR) on doxorubicin (DOX)-induced chronic heart failure (CHF) in rats by integrated approaches.
<b><i>Purpose:</i></b> To investigate a possible association between gene variants and patient response to treatment with intravitreal ranibizumab for neovascular age-related macular degeneration (AMD). <b><i>Methods:</i></b> Visual acuity score (VAS) was recorded at baseline subsequent visit 6 months. Genotypes of 3 polymorphisms in known AMD susceptibility loci (rs1061170 complement factor H (CFH), rs11200638 HTRA1 rs1413711 VEGF) were...
Abstract Acetaminophen (APAP)‐induced acute liver injury (AILI) is the most frequent cause of failure in developed countries. Trimethylamine N‐oxide (TMAO) a metabolite derived from gut microbiota and relatively high circulation elderly, individuals with diabetes, heart disease. Herein, we showed that TMAO exacerbates APAP hepatotoxicity. It possible delayed repair regeneration resulted reduced macrophage accumulation was responsible for this combined Moreover, matrix metalloproteinase 12...
A novel approach has been adopted for synthesizing green silver nanoparticles (AgNPs) over hemp/cotton blended woven fabrics. The nanosilvers were synthesized from the bark of mammoth pines (Sequoiadendron giganteum) through ensuring in situ synthesis protocol. AgNPs displayed brilliant color appearances on surfaces fabrics due to LSPR (localized surface plasmon resonance) effects. deposited quantified by X-ray fluorescence (XRF) tests solid samples and found significant presence metallic...