- Bacillus and Francisella bacterial research
- Rabies epidemiology and control
- Poxvirus research and outbreaks
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Liver Disease Diagnosis and Treatment
- Vector-Borne Animal Diseases
- Head and Neck Surgical Oncology
- Viral-associated cancers and disorders
- Hepatitis C virus research
- Neuroblastoma Research and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Virology and Viral Diseases
- Colorectal and Anal Carcinomas
- T-cell and Retrovirus Studies
- Organ Transplantation Techniques and Outcomes
- Ear and Head Tumors
- Virus-based gene therapy research
- Retinoids in leukemia and cellular processes
- Acupuncture Treatment Research Studies
- Angiogenesis and VEGF in Cancer
- Amoebic Infections and Treatments
- Head and Neck Cancer Studies
- Protein Tyrosine Phosphatases
- Fungal Biology and Applications
Sichuan University
2016-2020
State Key Laboratory of Biotherapy
2020
Jilin Province Tumor Hospital
2019
China Medical University
2018
Sun Yat-sen University
2013-2014
Sun Yat-sen University Cancer Center
2013
82th Hospital of Pla
2013
BACKGROUND The current study investigated the prevalence and prognostic value of chronic hepatitis B virus (HBV) infection in patients with nasopharyngeal carcinoma (NPC) from an area southern China which HBV NPC are endemic. METHODS A total 1301 nonmetastatic, histologically proven who were treated radiotherapy or chemoradiotherapy retrospectively reviewed. RESULTS In this series, 142 (10.9%) had (hepatitis surface antigen [HBsAg] seropositive). percentages non–cancer‐related deaths (15.0%...
Background . Ganoderma lucidum polysaccharides (GLP) has anti-inflammatory and immunomodulatory effects. Dysregulated immune responses are involved in the pathogenesis of dextran sulfate sodium (DSS)-induced colitis. The aim this study was to assess therapeutic potential GLP alleviate DSS-induced Methods mice were administered with by intragastric gavage daily for two weeks prior DSS treatment. Mice orally 2.5% dissolved drinking water or treatment 6 days. killed on day 7 after induction...
We aimed to evaluate the prognostic value of clinical and pathologic factors in rectal squamous cell carcinomas (SCC) construct a nomogram for their outcome prediction.The study cohort was selected from Surveillance, Epidemiology, End Results (SEER) program between January 2004 December 2013. Univariate multivariate analyses were performed using Cox proportional hazards regression model involved variables. All combined predict overall survival (OS), followed by discrimination as well...
Bovine herpesvirus 1 (BHV-1) has received increasing attention for its potential oncolytic applications. BHV-1 recognizes nectin-1 cell entry via viral glycoprotein D (gD) but represents a low-affinity binding virus. The molecular basis underlying this low receptor-binding affinity, however, remains unknown. Here, the crystal structures of gD in free and nectin-1-bound forms are presented. While showing an overall resembled mode to other alphaherpesvirus gDs, unique G-strand/α2-helix...
To ensure the high purity and biological activity of adenovirus vector to be used for clinical applications, a stable linearly scalable preparation method is highly imperative. During adenovirus-harvesting process, Triton X-100-based lysis possesses advantages higher efficiency as well easier linearization amplification. Most X-100 can removed from sample by chromatographic purification. However, there no report that small amount residual X-100, present in sample, affect particle integrity,...