Yuping Li

ORCID: 0000-0002-8032-3605
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About
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Research Areas
  • Biochemical and Molecular Research
  • RNA modifications and cancer
  • Regional Economic and Spatial Analysis
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Ferroptosis and cancer prognosis
  • Ubiquitin and proteasome pathways
  • Evaluation Methods in Various Fields
  • Genomics and Phylogenetic Studies
  • Elevator Systems and Control
  • Microbial Natural Products and Biosynthesis
  • Extracellular vesicles in disease
  • Peptidase Inhibition and Analysis
  • Pancreatic function and diabetes
  • Smart Parking Systems Research
  • Plant Pathogens and Fungal Diseases

Sichuan Cancer Hospital
2024

University of Electronic Science and Technology of China
2024

Zhengzhou Normal University
2017-2019

Shenyang Agricultural University
2018

ABSTRACT Selective screening of the population based on NSCLC risk is an effective technique for minimising overdiagnosis and overtreatment. Platelets components can be used as liquid‐biopsy markers, potentially assessing NSCLC, which are easily deployed in clinical applications. Platelet RNA sequencing datasets were analysed to identify specific genes derived from patients healthy donors. Then, expressions selected gene validated a trial. Not only availability differentiating donors but...

10.1111/jcmm.70544 article EN cc-by Journal of Cellular and Molecular Medicine 2025-04-01

<title>Abstract</title> Background While the PRP (platelet-rich plasma) method was most widely used in tumor-educated platelets (TEPs) research, there were still peripheral blood unextracted which are whose histology and function currently alien. Objectives To prove existed, to explore correlation of with lung cancer progression. Methods A second centrifugation step establish a modified approach, compared based on PRR (platelet recovery rate). Sequencing analysis platelets. Results The...

10.21203/rs.3.rs-4444704/v1 preprint EN cc-by Research Square (Research Square) 2024-05-31

Abstract Nicotinamide N ‐methyltransferase (NNMT) catalyzes the methyl transfer from universal donor S‐adenosyl methionine (SAM) to nicotinamide (NA) form ‐methylnicotinamide. This important process is related level of adenine dinucleotide (NAD + ) in vivo; thus, NNMT regarded as an drug target linked with various diseases. Although has been extensively studied area biology and medicine, detailed mechanism still not clear, especially aspect role solvents (water) enzyme catalysis. Here, we...

10.1002/poc.4093 article EN Journal of Physical Organic Chemistry 2020-06-30

Nicotinamide N-methyltransferase (NNMT), a key cytoplasmic protein in the human body, is accountable to catalyze nicotinamide (NCA) N1-methylation through S-adenosyl-L-methionine (SAM) as methyl donor, which has been linked many diseases. Although extensive studies have concerned about biological aspect, detailed mechanism study of enzyme function, especially part dynamics lacking. Here, wild-type together with mutation at position 20 Y20F, Y20G, and free tryptophan were carried out explore...

10.3906/biy-2101-54 article EN TURKISH JOURNAL OF BIOLOGY 2021-05-20

This essay makes relevant statistical analysis of the four aspects family income, wage transfer and property income rural households in Luoyang City based on SPSS.17. Through analysis, it can be concluded that farmers' promoted by actively promoting optimization geographical location, increasing industrial investment number enterprises, improving education output value, expanding employment channels development sideline businesses.

10.1109/icis46139.2019.8940253 article EN 2019-06-01

By measuring correlated variables in housing estates corresponding to different grades of roads Zhengzhou City, obtain the conclusion based on correlation values: saturated headway is low, average travel speed high high-grade estate, i.e. impact types estate openness road passage. Then mode and scale, propose reasonable suggestions for urban planning sector traffic administrative department from two aspects: income increase expenditure reduction.

10.1109/icis.2017.7960085 article EN 2017-05-01

In this paper, we carried out the statistics and cluster analysis of household operating income, wage transferable income property rural residents in Luoyang City by SPSS.17. After analysis, drew a conclusion that all districts counties can promote growth actively optimizing geographical position, increasing industrial investment enterprises, improving educational output value, employment channels developing sidelines.

10.1109/icis.2018.8466442 article EN 2018-06-01
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