William B. Young

ORCID: 0000-0002-8036-3666
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About
Contact & Profiles
Research Areas
  • Migraine and Headache Studies
  • Trigeminal Neuralgia and Treatments
  • Sympathectomy and Hyperhidrosis Treatments
  • Ophthalmology and Eye Disorders
  • Psychosomatic Disorders and Their Treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Olfactory and Sensory Function Studies
  • Neurological Disorders and Treatments
  • Cerebral Venous Sinus Thrombosis
  • Suicide and Self-Harm Studies
  • Botulinum Toxin and Related Neurological Disorders
  • Gallbladder and Bile Duct Disorders
  • Neurological Complications and Syndromes
  • Vestibular and auditory disorders
  • Neurosurgical Procedures and Complications
  • Anesthesia and Pain Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Maternal Mental Health During Pregnancy and Postpartum
  • Pediatric Hepatobiliary Diseases and Treatments
  • Medical Imaging and Pathology Studies
  • Anesthesia and Sedative Agents
  • Ophthalmology and Visual Health Research
  • Pain Management and Placebo Effect
  • Oropharyngeal Anatomy and Pathologies
  • Medical and Biological Sciences

Headache Care Center
1998-2024

Thomas Jefferson University
2012-2024

Thomas Jefferson University Hospital
2003-2020

Jefferson Hospital for Neuroscience
2014-2019

University of British Columbia
2011

Janssen Scientific Affairs (United States)
2010

Janssen (United States)
2010

Mayo Clinic
2010

Pacific Design Technologies (United States)
2009

Albert Einstein College of Medicine
2008

<h3>Objective</h3> Non-bacterial thrombotic endocarditis (NBTE) is a syndrome characterised by cardiac valve vegetations and/or thickening due to non-infective mechanisms. Nowadays, premortem diagnosis of NBTE possible based on echocardiographic findings. Therefore, better characterise this disease, we performed contemporary review the epidemiology, demographics, and clinical outcomes these patients. <h3>Methods</h3> Adults with seen within Mayo Clinic Enterprise from December 2014 2021 were...

10.1212/wnl.0000000000002918 article EN cc-by-nc-nd Neurology 2016-07-14

People who have a disease often experience stigma, socially and culturally embedded process through which individuals stereotyping, devaluation, discrimination. Stigma has great impact on quality of life, behavior, life chances. We do not know whether or migraine is stigmatizing.We studied 123 episodic patients, chronic 62 epilepsy patients in clinical setting to investigate the extent stigma attaches migraine, using as comparison. used scale for illness, 24-item questionnaire suitable...

10.1371/journal.pone.0054074 article EN cc-by PLoS ONE 2013-01-16

Hemicrania continua is an indomethacin-responsive headache disorder characterized by a continuous, moderate to severe, unilateral headache. More than 90 cases of hemicrania have been reported, but there still uncertainty about its clinical features.The authors compared 34 new (24 women, 10 men) with previously reported cases. All the patients met Goadsby and Lipton's proposed criteria. The baseline (continuous background headache) exacerbation (attacks severe periods headaches).The was...

10.1212/wnl.57.6.948 article EN Neurology 2001-09-25

Objective.—To determine whether there are any differences in health‐related quality of life between patients with migraine and those transformed migraine. Background.—There no published reports comparing the Methods.—We conducted a retrospective analysis examining seen at specialty headache clinic. Data collected included Short Form‐36 (SF‐36) Migraine Disability Assessment questionnaires as well demographic information. Both these forms part initial evaluation A t test Bonferroni correction...

10.1046/j.1526-4610.2001.041006573.x article EN Headache The Journal of Head and Face Pain 2001-06-01

To compare the clinical features of patients with chronic daily headache (CDH) idiopathic intracranial hypertension without papilledema (IIHWOP) to those normal CSF pressure.A case-control study was conducted at a tertiary center. Cases consisted 25 consecutive (24 women, 1 man, 38 +/- 6 years) IIHWOP diagnosed between June 1989 and 1996. if pressure 200 mm on two occasions there no papilledema. Control subjects refractory CDH who had lumbar puncture performed 1992 1996 (n = 60, 50 10 men,...

10.1212/wnl.51.1.245 article EN Neurology 1998-07-01

<b><i>Article abstract</i></b> Cluster headache with aura is rare. The authors retrospectively reviewed 101 cluster patient charts at the Jefferson Headache Center. Six patients had an associated aura, five visual and one olfactory, lasting 5 to 120 minutes. Only migraine (without aura). Auras always occurred or were followed by a severe headache. Two related.

10.1212/wnl.54.1.219 article EN Neurology 2000-01-11

Objective.—To evaluate the effect of GONB, with or without trigger point injection (TPI), on dynamic mechanical (brush) allodynia (BA) and head pain in migraine. Background.—Patients migraine often have cutaneous that is related to sensitization central neurons. Greater occipital nerve block (GONB) an effective treatment for headache; however, its unknown. Methods.—We studied patients BA who were treated GONB TPI. Demographic data, history, headache features documented. Allodynia was...

10.1111/j.1526-4610.2005.05073.x article EN Headache The Journal of Head and Face Pain 2005-04-01

The treatment of a migraine attack can be difficult when first-line medication is unsuccessful and options for parenteral "rescue" therapy are limited.A randomized, double-blind, placebo-controlled, dose-ranging, multicenter study was conducted to assess the efficacy tolerability droperidol 0.1 mg, 2.75 5.5 8.25 mg acute moderate severe headache in adults.A total 331 patients were enrolled; 305 treated. Headache response at 2 hours better (p < 0.002) groups receiving IM doses (87%), (81%),...

10.1212/01.wnl.0000042477.63516.b2 article EN Neurology 2003-01-28

Migraine is a common chronic neurological disease that disproportionately affects women. has significant negative effects on physical, emotional, and social aspects of health, can be costly for patients, employers, society as whole. Growing evidence supports the roles sex gender in migraine risk, pathophysiology, presentation, diagnosis, treatment, management. However, differences have received limited attention, which impede advancements detection, care, education. The Society Women's...

10.1089/jwh.2018.7274 article EN Journal of Women s Health 2018-08-01

Introduction: Triptans, the most commonly prescribed acute treatments for migraine attacks are, per FDA labeling, contraindicated in cardiovascular (CV) disease patients and have warnings precautions those with CV risk factors. Methods: Headache specialists, cardiologists, health economics outcomes researchers convened to identify diagnostic codes for: (1) diseases contraindicating triptans based on labeling; (2) conditions comprising “other significant underlying disease”; (3) factors...

10.1177/2150132720963680 article EN cc-by-nc Journal of Primary Care & Community Health 2020-01-01

Olanzapine, a thienobenzodiazepine, is new "atypical" antipsychotic drug. Olanzapine's pharmacologic properties suggest it would be effective for headaches, and its propensity inducing acute extrapyramidal reactions or tardive dyskinesia relatively low. We thus decided to assess the value of olanzapine in treatment chronic refractory headache.We reviewed records 50 patients with headache who were treated at least 3 months. All previously had failed four preventative medications. The daily...

10.1046/j.1526-4610.2002.02126.x article EN Headache The Journal of Head and Face Pain 2002-06-01

Headache is a common, disabling disorder that frequently not well managed in general clinical practice.To determine if patients cared for coordinated headache management program would achieve reduced disability compared with usual care.A randomized controlled trial of vs care.Three distinctly different practice sites: an academic internal medicine located major east coast city, staff-model care organization west and community medium-sized city the southeast. Patients.- Individuals 21 years...

10.1111/j.1526-4610.2007.01148.x article EN Headache The Journal of Head and Face Pain 2008-06-10

1. Myositis ossificans as a complication of tetanus is described. 2. Ossification in mesodermal tissue briefly discussed.

10.1302/0301-620x.41b3.535 article EN Journal of Bone and Joint Surgery - British Volume 1959-08-01

1. Details of clinical, radiological, biochemical and histological investigations a case metaphysial dysostosis are presented. 2. The patient was boy seven years, showed widespread lesions (involving long bones limbs, small hands feet, pelvis, clavicles, ribs) characterised by retardation growth ossification with masses partly calcified tissue in the metaphyses. 3. No clinical or evidence renal osteodystrophy found described. 4. Metaphysial is discussed relation to other chondrodystrophies.

10.1302/0301-620x.36b4.622 article EN Journal of Bone and Joint Surgery - British Volume 1954-11-01

Colloid cysts of the third ventricle are benign tumors that may cause brief, severe headache and, rarely, death. We present a patient with frequent, episodic, headaches 2 weeks' duration who suddenly became obtunded. reviewed literature on symptomatology colloid and conclude any patient: less than 1‐year history suggestive ventricular cyst causing should be aggressively investigated.

10.1046/j.1526-4610.1997.3701015.x article EN Headache The Journal of Head and Face Pain 1997-01-01
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