A5005604647- Anesthesia and Pain Management
- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Infective Endocarditis Diagnosis and Management
- Hydrogels: synthesis, properties, applications
- Synthesis and Reactivity of Heterocycles
- Extraction and Separation Processes
- Microfluidic and Capillary Electrophoresis Applications
- Dental Research and COVID-19
- Dental Anxiety and Anesthesia Techniques
- Ultrasound and Hyperthermia Applications
- Nosocomial Infections in ICU
- Synthesis and pharmacology of benzodiazepine derivatives
- Ultrasound and Cavitation Phenomena
- Adsorption and biosorption for pollutant removal
- Synthesis of heterocyclic compounds
- Cardiac Arrest and Resuscitation
- Cyclopropane Reaction Mechanisms
- Synthesis and biological activity
- Congenital Heart Disease Studies
- Streptococcal Infections and Treatments
- Shoulder Injury and Treatment
- Synthesis and Biological Evaluation
- Pancreatic function and diabetes
- Organoselenium and organotellurium chemistry
Mansoura University
2016-2025
The University of Texas Southwestern Medical Center
2021-2025
Valley Health System
2023-2025
Maharishi Markandeshwar University, Mullana
2023
Institute of Medical Sciences
2023
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences
2023
MedStar Heart & Vascular Institute
2023
Minia University
2019-2023
Gandhi Medical College & Hospital
2023
Universiti Teknologi MARA
2023
Since the first report of organoselenium compound, ebselen, as a potent inhibitor SARS-CoV-2 Mpro main protease by Z. Jin et al. (Nature, 2020), different OSe analogs have been developed and evaluated for their anti-COVID-19 activities. Herein, organoselenium-clubbed Schiff bases were synthesized in good yields (up to 87%) characterized using spectroscopic techniques. Their geometries studied DFT B3LYP/6-311 (d, p) approach. Ten FDA-approved drugs targeting COVID-19 used model pharmacophores...
<title>Abstract</title> <bold>Background</bold> Heart failure with reduced ejection fraction (HFrEF) requires adherence to guideline-directed medical therapy (GDMT) for optimal outcomes. This study aimed assess GDMT at a teaching hospital and compare discharge prescriptions by residents attending physicians. <bold>Methods</bold> A retrospective cohort was conducted Spring Valley Hospital from August 2023 March 2024. Patients HFrEF decompensated heart as the primary reason admission were...
Hemicrania continua is an indomethacin-responsive headache disorder characterized by a continuous, moderate to severe, unilateral headache. More than 90 cases of hemicrania have been reported, but there still uncertainty about its clinical features.The authors compared 34 new (24 women, 10 men) with previously reported cases. All the patients met Goadsby and Lipton's proposed criteria. The baseline (continuous background headache) exacerbation (attacks severe periods headaches).The was...
This review reports the reactivity of indolizines. The reactions section covers, in general, electrophilic, oxidation, reduction, addition, cycloaddition, condensation, and Mannich multicomponent reactions. synthesis bis-indolizines cyclazines are reported. reaction mechanisms discussed.
We report the synthesis of an amphiphilic triblock copolymer composed a hydrophilic poly(ethylene glycol) (PEG) block, central poly(acrylic acid) (PAA) and hydrophobic poly(methyl methacrylate) (PMMA) block using atom transfer radical polymerization technique. examined self-assembly PEG-b-PAA-b-PMMA copolymers in aqueous solutions forming nanosized micelles their ability to encapsulate guest molecules such as Nile Red (NR) dye cabazitaxel (CTX, anticancer drug). used...
Abstract In this work, an ion‐imprinted polymeric material based on functionalized phenolic resin was developed for the efficient selective removal of Cu 2+ ions from aqueous solution. p‐ Aminophenol‐isatin Schiff base ligand (HPIS) first synthesized and combined with to prepare corresponding complex [Cu(PIS) 2 ]. The along its copper fully investigated characterized before anchoring in a base‐catalyzed condensation copolymerization formaldehyde resorcinol. were removed obtained construction...
Eculizumab is a biologic medication used for the treatment of complement-related disorders including anti-acetylcholine receptor antibody-positive generalized myasthenia gravis. It targets C5 complement, preventing its cleavage into active terminal components. Thus, vaccination against encapsulated organisms advised before starting this treatment. also has critical role Cryptococcus neoformans infection. Here, we present case 34-year-old man with history gravis who was treated prednisone and...
BackgroundWe evaluated the safety and efficacy of thoracic paravertebral block as a method pain relief after thoracotomy in comparison with systemic opioids.Study designRandomized controlled trial.MethodsWe scheduled 40 patients divided into two groups to receive either 20 ml bupivacaine (0.5%) incremental injections for intra postoperative analgesia via catheter inserted space. The other received morphine analgesia. We recorded Visual Analog Scale score, total consumption, time first...
Acute pancreatitis (AP) is the most common cause of gastroenterological hospitalization in USA, with a mortality ranging from 5 to 20%. Up 80% cases are caused by cholelithiasis and alcohol abuse. Less etiologies that need be explored include hypertriglyceridemia, trauma, ERCP, infections, drugs. A number medications known acute pancreatitis, 0.3-1.4% all being drug induced (DIP). Here, we present case metronidazole-induced pancreatitis.
A series of tetrahydropyrimidines and bis‐(tetrahydropyrimidines) was synthesized by Mannich reaction sec ‐emaminones with formaldehyde the appropriate amine or diamine. Whereas gave dihydro‐1,3‐oxazine. Tetrahydropyrimidines incorporating a phenolic base were obtained tetrahydropyrimidine. The bis( ‐enaminones) used as precursors in synthesis bis(tetrahydropyrimidines) bis(dihydro‐1,3‐oxazines). Treatment ‐emaminone ‐enaminone) hydrazine hydrate phenylhydrazine suitable aldehyde afforded...
Type 1 diabetes stem-cell-based treatment approach is among the leading therapeutic strategies for treating cardiac damage owing to stem cells' regeneration capabilities. Mesenchymal cells derived from adipose tissue (AD-MSCs) have shown great potential in diabetic cardiomyopathy (DCM). Herein, we explored antioxidant-supporting role of N, N'-diphenyl-1,4-phenylenediamine (DPPD) enhancing MSCs' alleviating DCM complications heart tissues type rats. Six male albinos Wistar rat groups been...