A5093471662- Psoriasis: Treatment and Pathogenesis
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Health and Medical Studies
- Pharmaceutical studies and practices
- Autoimmune Bullous Skin Diseases
Medical University of Graz
2023-2025
Abstract Background Generalized pustular psoriasis (GPP) is a rare, inflammatory skin disease characterized by widespread eruption of sterile pustules with or without systemic symptoms. Objectives This study aimed to describe the demographics patients GPP in Central and Eastern Europe (CEE), present clinical characteristics individual flares explore current treatment landscape. Methods Patient were collected at times last observation previous treatment. Characteristics patient's (most...
Due to similarities, the distinction between generalized pustular psoriasis (GPP) and acute exanthematous pustulosis (AGEP) has been a matter of debate for long time. Our aim was define molecular features GPP AGEP. We analyzed skin biopsy samples clinical data from 125 patients with AGEP, GPP, palmoplantar (PPP), plaque (PSO), non-pustular cutaneous adverse drug reactions (ADRs), as well healthy controls using RNA sequencing blinded histopathological analyses. The transcriptome...
Zusammenfassung Hintergrund und Ziele In dieser Studie wurde untersucht, inwieweit die Einführung wirksamerer Medikamente in jüngster Zeit zu einer Verbesserung der Behandlungsergebnisse von Psoriasis‐Patienten im klinischen Alltag geführt hat. Patienten Methodik Es wurden Patientencharakteristika Wirksamkeit Therapie ersten Behandlungsjahr bei Biologika‐naiven 2004 bis heute analysiert, unabhängig Therapiewechseln. Ergebnisse Die Daten 2729 eigneten sich für Analyse. Der Anteil weiblichen...