A5090646040- Syphilis Diagnosis and Treatment
- Genital Health and Disease
- Reproductive tract infections research
- Psoriasis: Treatment and Pathogenesis
- Skin Diseases and Diabetes
- Dermatology and Skin Diseases
- Cutaneous Melanoma Detection and Management
- Herpesvirus Infections and Treatments
- Drug-Induced Adverse Reactions
- Autoimmune Bullous Skin Diseases
- Diverticular Disease and Complications
- Poxvirus research and outbreaks
- Nonmelanoma Skin Cancer Studies
- Parvovirus B19 Infection Studies
- HIV/AIDS Research and Interventions
- Oral Health Pathology and Treatment
- Cancer and Skin Lesions
- Autoimmune and Inflammatory Disorders
- Asthma and respiratory diseases
- HIV/AIDS oral health manifestations
- Immunodeficiency and Autoimmune Disorders
- Metastasis and carcinoma case studies
- Historical Medical Research and Treatments
- Eosinophilic Disorders and Syndromes
- Ear and Head Tumors
Medical University of Graz
2018-2024
Austrian Society of Dermatology and Venereology
2020-2024
Treatment of prurigo nodularis (PN) is challenging and new treatment options are needed.To evaluate the efficacy safety two oral doses kappa opioid agonist mu antagonist nalbuphine extended release (NAL-ER) tablets in a phase 2, multicentre, randomized, double-blind, placebo-controlled trial with an open-label, 50-week extension phase.Subjects moderate-to-severe PN were randomized to NAL-ER 81 mg (NAL-ER81) or 162 (NAL-ER162) twice-daily placebo for 8 weeks stable dosing following 2-week...
Summary Background and Objectives Serovar L1–L3 of Chlamydia trachomatis (CT) causes lymphogranuloma venereum (LGV). A surge in LGV‐cases has been observed among HIV‐positive men who have sex with (MSM). Discrimination between LGV non‐LGV is pivotal since it major treatment implications. Here, we aimed to determine the prevalence characteristics CT‐infections. Patients Methods All CT‐positive results from 04/2014–12/2021 at four largest Austrian HIV STI clinics were evaluated. Disease...
Abstract With the introduction of latest class biologic drugs targeting interleukin (IL)-23p19, three new, highly effective can be used for treatment chronic plaque psoriasis. However, poorer skin improvement as well higher rates serious adverse events have been reported patients under real-world conditions (outside clinical trials). This accounts especially who already treated with drugs. We therefore aimed to determine effectiveness and safety IL-23p19 inhibitors in by analysing data from...
Syphilis is a curable systemic infectious disease with clear increase in incidence recent years. The presents broad clinical spectrum and challenges clinicians due to the long incubation period sometimes complex interpretation of serological test results. Penicillin G remains treatment choice all stages syphilis.
The incidence of sexually transmitted infections (STIs) is unbridled and on the rise. Extragenital STIs (anal pharyngeal infections) are commonly asymptomatic, resulting in delayed diagnosis treatment consequently higher chances onward transmission.
Abstract Background Dermatological research has traditionally concentrated on evaluating mental comorbidities, neglecting positive concepts like happiness. Initial studies indicate that psoriasis and atopic dermatitis (AD) impair the happiness of those affected. Considering global variations, this study aimed to explore disease‐ country‐specific differences in disease‐related quality life happiness, potential influential factors heuristic among AD patients Europe. Methods A cross‐sectional...
Summary Background and Objectives This study analyzed the extent to which recent introduction of more effective treatments has led an improvement in real‐world psoriasis patients. Patients Methods Patient characteristics first‐year treatment effectiveness biologic‐naive patients have been since 2004 until now, irrespective switches. Results Data from 2,729 were eligible for this analysis. The proportion female increased significantly over years 29.9% 36.2% (p < 0.028), while number with...
Mycoplasma genitalium (MG) is an emerging sexually transmitted infection, often harboring resistance-associated mutations to azithromycin (AZM). Global surveillance has been mandated tackle the burden caused by MG, yet no data are available for Austria. Thus, we aimed investigate prevalence of disease characteristics, and treatment outcomes at largest Austrian HIV-and STI clinic.
Melanocytic nevi have a complex evolution influenced by several endogenous and exogenous factors are known risk for malignant melanoma. Interestingly, tobacco use seems to be inversely associated with melanoma risk. However, the association between lentigines has not yet been evaluated.We investigated prevalence of nevi, atypical in relation smoking cohort 59 smokers 60 age- sex-matched nonsmokers, using questionnaire performing total body skin examination experts.No significant differences...
Lymphogranuloma venereum (LGV) ist eine sexuell übertragene Erkrankung verursacht durch Chlamydia trachomatis (CT), Serovar L1-L3. Eine Zunahme von LGV vorwiegend bei Männern, die Sex mit Männern haben (MSM), beobachtet worden. Die Unterscheidung zwischen und Nicht-LGV-Serovaren hat therapeutische Konsequenzen, daher wurden Prävalenz Charakteristika innerhalb aller CT-Infektionen untersucht.
Zusammenfassung Hintergrund und Ziele In dieser Studie wurde untersucht, inwieweit die Einführung wirksamerer Medikamente in jüngster Zeit zu einer Verbesserung der Behandlungsergebnisse von Psoriasis‐Patienten im klinischen Alltag geführt hat. Patienten Methodik Es wurden Patientencharakteristika Wirksamkeit Therapie ersten Behandlungsjahr bei Biologika‐naiven 2004 bis heute analysiert, unabhängig Therapiewechseln. Ergebnisse Die Daten 2729 eigneten sich für Analyse. Der Anteil weiblichen...
We present the case of a 66-year-old bisexual patient suffering from painful bloody defecation, linked to rectal thickening, rectovesical fistula and enlarged lymph nodes in mesorectal area. The was misdiagnosed with cancer (T3 N2) on MRI but symptoms were due lymphogranuloma venereum. After adequate treatment doxycycline, faded within days; control showed complete regression all pathologic alterations.
Abstract is missing (Short communication)
A 60-year-old man presented due to two centrally crustose pustules on the penis of 1 week duration. The patient denied any unprotected sexual intercourse; however, admitted protected contact with a male random acquaintance. local trauma, manipulation, or previous pathologies at that other site. He also reported having fever day before. was diagnosed HIV 14 years previously and maintained good immune-virological control under antiretroviral treatment. In addition his history HIV, he had high...
A 50-year-old man presented with a broad ulcerated lesion on the glans penis, persisting for 3 weeks since spa stay some before. He had been seen by dermatologist in preceding weeks, who prescribed various topicals, including dexpanthenol, gentamicin, resin salve, clotrimazole, and octenidinine dihydrochloride 2-phenoxyethanol. Serology syphilis was negative. As ulcer persisted, patient sent to our department diagnostic re-evaluation. The did not take any medication regular basis denied...