A5017266518- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Soft tissue tumor case studies
- Musculoskeletal synovial abnormalities and treatments
- Gastrointestinal disorders and treatments
- Oral and Maxillofacial Pathology
- MRI in cancer diagnosis
- Advanced X-ray and CT Imaging
- Neuroblastoma Research and Treatments
- Orthopedic Surgery and Rehabilitation
- Prostate Cancer Treatment and Research
- Management of metastatic bone disease
- Gastrointestinal Tumor Research and Treatment
- Cardiac tumors and thrombi
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Gastroesophageal reflux and treatments
- Trace Elements in Health
- Pancreatic and Hepatic Oncology Research
- Foot and Ankle Surgery
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Inflammatory Myopathies and Dermatomyositis
- Skin and Cellular Biology Research
Medical University of Graz
2020-2025
Polytechnic of Međimurje in Čakovec
2008-2016
Fusions involving NTRK1, NTRK2, and NTRK3 are oncogenic drivers occurring in a spectrum of mesenchymal neoplasms ranging from benign to highly malignant tumors. To gain further insights into the staining profile with pan-TRK assay, we analyzed large number soft tissue sarcomas correlated our findings molecular testing. Additionally, expand NTRK-fusion tumors by reporting lesion lung as well skin fibrous histiocytoma NTRK-fusion. We retrospectively reviewed diagnosed at Diagnostic Research...
Demographic and environmental factors determine the incidence of survival with malignancies, including sarcoma [1]. Accordingly, annual soft tissue sarcomas (STS) has markedly increased since early 2000s [2, 3]. Likewise, there appears to be an overall increase in bone (BS) 1975 [4, 5]. In parallel, one study reports moderate improvement adult patients BS STS up 2007 [6]. Previous studies were often based on cancer registries low coverage rates [3, 7, 8], focused limited time periods 9, 10],...
Hallux rigidus is degenerative arthritis of the first metatarsophalangeal joint characterized by pain and stiffness in with limitation motion functional impairment. Recently, bone grafts have been introduced orthopedic procedures, namely osteosynthesis arthrodesis. Allografts can induce formation, provide support for vascular ingrowth a low risk immunological rejection. A 52-year-old female patient hallux underwent arthrodesis using Shark Screw® made allogenic cortical bone. Corrective...
In the last decade, new tumor entities have been described, including EWSR1/FUS::NFATC2-rearranged neoplasms of different biologic behavior. To gain further insights into behavior these tumors, we analyzed a spectrum and discuss their key diagnostic molecular features in relation to prognosis. We report five patients with neoplasms, one simple bone cyst (SBC), two complex cystic lesions lacking morphological characteristics SBC, sarcomas. three cases, fluorescence situ hybridization (FISH)...
Abstract Prostate cancer (PC) is one of the most common cancers affecting men worldwide, with a high recurrence rate after therapy. 68 Ga-PSMA-11 and 18 F-fluciclovine are PET imaging tracers for detection sites in PC patients. membrane antigen overexpressed by tumor cells, whereas targets increased amino acid transporter cells. We report case an 83-year-old man known oligodendroglioma biochemically recurrent who shows focal uptake brain.
Summary Background Osteoid osteomas of the foot are rare, with a varying and atypical clinical as well radiological presentation impeding early diagnosis treatment. The aim present multicentre study was to 1) analyze epidemiological, findings patients osteoid 2) deduce diagnostic algorithm based on findings. Methods A total 37 (25 males, 67.6%, mean age 23.9 years, range 8–57 years) were retrospectively included, treated between 2000 2014 at 6 participating tertiary tumor centres....
Abstract Background Artificial bone graft substitutes (ABGS) for curettage of tumors are becoming increasingly popular. The aim this retrospective analysis was to determine the efficacy ABGS Cerasorb (Curasan-AG, Kleinostheim, Germany), a beta-tricalcium phosphate (beta-TCP), concerning resorption profile, healing, and remodeling after surgery evaluate potential complications. Methods Forty-three patients suffering from benign low-grade malignant were treated with refilling bony cavity using...
Background and purpose — Cat scratch disease (CSD) is a self-limiting caused by Bartonella (B.) henselae. It characterized granulomatous infection, most frequently involving lymph nodes. However, it can present with atypical symptoms including musculoskeletal manifestations, posing diagnostic challenge. We describe the prevalence demographics of CSD cases referred to sarcoma center, radiological, histological, molecular findings.Patients methods Our cohort comprised 10 patients, median age...
Guidelines for previous negative biopsy (PNB) cohorts with a suspicion of prostate cancer (PCa) after positive multiparametric (mp) magnetic-resonance-imaging (MRI) often favour the fusion-guided targeted prostate-biopsy (TB) only approach Prostate Imaging-Reporting and Data System (PI-RADS) ≥3 lesions. However, recommendations lack direct performance comparison within naïve (BN) vs. PNB patients its prognostication whole mount pathology report (WMPR), respectively. We suppose, that...
Background.Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal of digestive tract.These can not be simply divided into benign and malignant forms.There is a continuum from to forms.The tumour size mitotic activity have strong influence on GISTs behaviour.Tumour behaviour also varies according site origin.The origin anywhere along tract, in mesentery or omentum.GISTs mainly tumours, about 70-80%, usually found gastric wall.We report case 70-year old female with form...
Background. Nodular fasciitis (NF) is a self-limiting, benign mesenchymal neoplasm of fibroblastic/myofibroblastic origin. Due to the fast growth, cellularity, and frequently observed high mitotic count, it commonly misdiagnosed as sarcoma, often resulting in overtreatment. Intraarticular examples NF are extremely rare. Radiologically, can mimic fibroma tendon sheath, tenosynovial giant cell tumor, synovial chondromatosis. Histology vary from hypercellular, mitotically active lesions...
Primitive neuroectodermal tumor (PNET)/Ewing's sarcoma (EWS) belongs to a family of neoplasms that are presumed originate from the crest. PNET/EWSs highly aggressive malignancies usually present in form bone or soft tissue masses and affect adolescents young adults. Primary PNET/EWS kidney is very rare.We case 32-year-old female patient with primary renal diagnosed nine years eight months earlier. The presented acute flank pain left lumbar region, hematuria, episodes high body temperature...
Cellular myxoma is a benign soft tissue tumor frequently associated with GNAS mutation that may morphologically resemble low-grade myxofibrosarcoma. This study aimed to identify the undescribed methylation profile of cellular and compare it We performed molecular analysis on twenty myxomas nine myxofibrosarcomas analyzed results using methylation-based DKFZ sarcoma classifier. A total 90% had mutations (four loci not been previously described). Copy number variations were found in all but...
Abstract Objective We aim to evaluate the efficacy of CT-guided percutaneous radiofrequency ablation (RFA) and surgical treatment in osteoid osteoma (OO) treated at Medical University Graz. Materials methods In a single-institution study, we analysed data from January 2005 2021 patients with histological/radiological diagnosis OO. CT MRI scans were reviewed for typical findings. Means (with SD) medians IQR) reported normally non-normally distributed variables. Differences between groups...
Abstract Purpose To evaluate the correlation between ectopic adipose tissue and iron overload severity in patients with hemochromatosis. Material methods A retrospective cohort of 52 who underwent liver concentration quantification from January 2015 to October 2023 using a 3.0T MRI scanner. R2* relaxation times proton density fat fraction (PDFF) were assessed for entire volume specific region interest (ROI) placed right lobe. Total body (TF), subcutaneous (SCF), intermuscular (IMF), visceral...
Kurzzusammenfassung Nodular fasciitis (NF) is a self-limiting, benign mesenchymal neoplasm of fibroblastic/myofibroblastic origin. Due to its fast growth, cellularity and frequently observed high mitotic count, it commonly misdiagnosed as malignant tumor, often resulting in overtreatment. Intraarticular examples NF are rare. Radiologically, can mimic fibroma the tendon sheath, tenosynovial giant cell tumor or synovial chondromatosis. Recently, MYH9-USP6 fusion has been found up 92% NF’s....