A5047616627- Mast cells and histamine
- Eosinophilic Disorders and Syndromes
- Asthma and respiratory diseases
- Urticaria and Related Conditions
- Food Allergy and Anaphylaxis Research
- Breast Cancer Treatment Studies
- Molecular Biology Techniques and Applications
- Drug-Induced Adverse Reactions
- Acute Myeloid Leukemia Research
- Cervical Cancer and HPV Research
- Autoimmune Bullous Skin Diseases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Gene expression and cancer classification
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- melanin and skin pigmentation
- Prostate Cancer Treatment and Research
- Cutaneous Melanoma Detection and Management
- Allergic Rhinitis and Sensitization
- Click Chemistry and Applications
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Veterinary Oncology Research
Paracelsus Medical University
2016-2025
University of Salzburg
2017-2024
Ludwig-Maximilians-Universität München
2011-2023
University of Tübingen
2002-2023
Misgav Ladach
2022
Universidad de Salamanca
2022
Gdańsk Medical University
2012-2021
Medical University of Vienna
2021
Unfallkrankenhaus Salzburg
2018-2020
Salzburger Landeskliniken
2017-2018
Activation of tissue mast cells (MCs) and their abnormal growth accumulation in various organs are typically found primary MC disorders also referred to as mastocytosis. However, increasing numbers patients now being informed that clinical findings due activation (MCA) is neither associated with mastocytosis nor a defined allergic or inflammatory reaction. In other MCA, MCs appear be clonal cells, but criteria for diagnosing not met. A working conference was organized 2010 the aim define MCA...
Advanced systemic mastocytosis comprises rare hematologic neoplasms that are associated with a poor prognosis and lack effective treatment options. The multikinase inhibitor midostaurin inhibits KIT D816V, primary driver of disease pathogenesis. We conducted an open-label study oral at dose 100 mg twice daily in 116 patients, whom 89 mastocytosis-related organ damage were eligible for inclusion the efficacy population; 16 had aggressive mastocytosis, 57 neoplasm, mast-cell leukemia. outcome...
// Peter Valent 1,2 , Attilio Orazi 3 David P. Steensma 4 Benjamin L. Ebert 5 Detlef Haase 6 Luca Malcovati 7 Arjan A. van de Loosdrecht 8 Torsten Haferlach 9 Theresia M. Westers Denise Wells 10 Aristoteles Giagounidis 11 Michael Loken Alberto Orfao 12 Lübbert 13 Arnold Ganser 14 Wolf-Karsten Hofmann 15 Kiyoyuki Ogata 16 Julie Schanz Marie C. Béné 17 Gregor Hoermann 18 Wolfgang R. Sperr Karl Sotlar 19 Bettelheim 20 Reinhard Stauder 21 Pfeilstöcker 22 Hans-Peter Horny...
ABSTRACT A nested multiplex PCR (NMPCR) assay that combines degenerate E6/E7 consensus primers and type-specific was evaluated for the detection typing of human papillomavirus (HPV) genotypes 6/11, 16, 18, 31, 33, 35, 39, 42, 43, 44, 45, 51, 52, 56, 58, 59, 66, 68 using HPV DNA-containing plasmids cervical scrapes ( n = 1,525). The performance NMPCR relative to conventional with MY09-MY11 GP5+-GP6+ primers, these two primer sets (MY/GP) in 495 corresponding histologic cytologic findings....
ABSTRACT The productive cycle of human papillomaviruses (HPVs) can be divided into discrete phases. Cell proliferation and episomal maintenance in the lower epithelial layers are followed by genome amplification expression capsid proteins. These events, which occur all infections, distinguished using antibodies to viral gene products or surrogate markers their expression. Here we have compared precancerous lesions caused HPV type 16 (HPV16) with types that not generally associated cancer....
Becoming invasive is a crucial step in breast cancer oncogenesis. At this point, lesion carries the potential for spreading and metastasis--a process, whose molecular characteristics still remain poorly understood. In article, we describe matched-pair analysis of ductal carcinoma situ (DCIS) (IDC) nine carcinomas to identify novel markers characterizing transition from DCIS IDC. The purpose study was better understand biology candidate genes products might serve as prognostic and/or targets...