Bogusław Nedoszytko

ORCID: 0000-0002-6286-0693
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About
Contact & Profiles
Research Areas
  • Mast cells and histamine
  • Urticaria and Related Conditions
  • Cutaneous lymphoproliferative disorders research
  • Dermatology and Skin Diseases
  • Food Allergy and Anaphylaxis Research
  • Asthma and respiratory diseases
  • Psoriasis: Treatment and Pathogenesis
  • Allergic Rhinitis and Sensitization
  • Lymphoma Diagnosis and Treatment
  • melanin and skin pigmentation
  • Sarcoma Diagnosis and Treatment
  • T-cell and Retrovirus Studies
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology
  • Drug-Induced Adverse Reactions
  • Cancer Genomics and Diagnostics
  • Immune Cell Function and Interaction
  • Acne and Rosacea Treatments and Effects
  • Polyamine Metabolism and Applications
  • Immunotherapy and Immune Responses
  • Ovarian cancer diagnosis and treatment
  • Cytokine Signaling Pathways and Interactions
  • Digestive system and related health
  • Epigenetics and DNA Methylation
  • Vitamin D Research Studies

Gdańsk Medical University
2015-2024

Medical University of Vienna
2021

Hospital Virgen del Valle
2021

University of Gdańsk
2014

Activation of tissue mast cells (MCs) and their abnormal growth accumulation in various organs are typically found primary MC disorders also referred to as mastocytosis. However, increasing numbers patients now being informed that clinical findings due activation (MCA) is neither associated with mastocytosis nor a defined allergic or inflammatory reaction. In other MCA, MCs appear be clonal cells, but criteria for diagnosing not met. A working conference was organized 2010 the aim define MCA...

10.1159/000328760 article EN International Archives of Allergy and Immunology 2011-10-27

Abstract Mastocytosis is an emerging differential diagnosis in patients with more or less specific mediator‐related symptoms. In some of these patients, typical skin lesions are found and the mastocytosis can be established. other cases, however, absent, which represents a diagnostic challenge. light this unmet need, we developed algorithm for suspected mastocytosis. adult skin, bone marrow ( BM ) biopsy should considered, regardless basal serum tryptase concentration. adults without who...

10.1111/all.12436 article EN Allergy 2014-05-19

Mast cell activation (MCA) is common and occurs in a number of pathologic conditions, including IgE-dependent independent allergic reactions, atopic disorders, autoimmune processes, mastocytosis. In subset patients, no underlying disease known trigger MCA are found. When the symptoms severe, systemic, recurrent, accompanied by diagnostic increase serum tryptase level or other mast mediators, an syndrome (MCAS) may be diagnosed. these typically respond to drugs suppressing MCA, mediator...

10.1016/j.jaip.2022.05.007 article EN cc-by The Journal of Allergy and Clinical Immunology In Practice 2022-05-25

Abstract Multicolor fluorescent in situ hybridization (FISH) was used to identify acquired chromosomal aberrations 12 patients with mycosis fungoides or Sézary syndrome, the most common forms of primary cutaneous T-cell lymphoma (CTCL). The frequently affected chromosome 12, which showed clonal deletions translocations a break point 12q21 12q22 five seven consecutive syndrome and monosomy sixth patient. balanced translocation t(12;18)(q21;q21.2), mapped minimal region two deletions, fine...

10.1158/0008-5472.can-04-0366 article EN Cancer Research 2005-09-15
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