A5044555694- Cannabis and Cannabinoid Research
- Smoking Behavior and Cessation
- Advanced Chemical Sensor Technologies
- Nicotinic Acetylcholine Receptors Study
- Indoor Air Quality and Microbial Exposure
- Forensic Toxicology and Drug Analysis
- Psychedelics and Drug Studies
- Neuroscience of respiration and sleep
- Coffee research and impacts
- Air Quality and Health Impacts
- Nutritional Studies and Diet
- Fatty Acid Research and Health
- Sleep and Wakefulness Research
- Cerebrovascular and Carotid Artery Diseases
- Biochemical Analysis and Sensing Techniques
- GABA and Rice Research
- Analytical Chemistry and Chromatography
- Infant Health and Development
- Folate and B Vitamins Research
University of Rochester Medical Center
2021-2023
Portland State University
2017-2021
E-cigarette aerosol emission studies typically focus on benchmarking toxicant levels versus those of cigarettes. However, such do not fully account for the distinct chemical makeup e-liquids and their unique properties. These approaches often conclude that there are fewer lower toxins produced by e-cigarettes than In 2015, we reported discovery new hemiacetals derived from reaction formaldehyde e-liquid solvents. The main finding was they constituted a significant proportion potentially...
Cannabis e-cigarettes containing Δ
Inhalable, noncombustible cannabis products are playing a central role in the expansion of medical and recreational use cannabis. In particular, practice "dabbing" with butane hash oil has emerged great popularity states that have legalized Despite their growing popularity, degradation product profiles these new not been extensively investigated. The study herein focuses on chemistry myrcene other common terpenes found extracts. Methacrolein, benzene, several concern to human health were...
Consumption of cannabis by nontraditional methods has surged since the advent legalization in North America and worldwide. Inhaling extracts using vaporizers via dabbing risen popularity, while concerns over product safety have not hindered their proliferation. The work herein is first step toward assessing vaporizing concentrated as a function gas-phase reaction products. thermal degradants Δ9-tetrahydrocannabinol (THC) been previously investigated. It was found that users may be exposed to...
The outbreak of e-cigarette or vaping product use-associated lung injury (EVALI) has been cause for concern to the medical community, particularly given that this novel illness coincided with COVID-19 pandemic, another severe pulmonary illness. Though cannabis e-cigarettes tainted vitamin E acetate were primarily associated EVALI, acute injuries stemming from inhalation reported in literature prior 2019, and it suggested components additives other than may be responsible. Despite these...
Flavoring chemicals in electronic nicotine delivery systems have been shown to cause cellular inflammation; meanwhile, the effects of fruit and tobacco flavors on lung inflammation by nose-only exposures mice are relatively unknown. We hypothesized that exposure flavored e-cigarettes would C57BL/6 J mice. The were exposed air, propylene glycol/vegetable glycerin, e-liquids: Apple, Cherry, Strawberry, Wintergreen, Smooth & Mild Tobacco, one hour per day for three days. Quantification...
Dabbing and vaping cannabis extracts have gained large popularity in the United States as alternatives to smoking, but diversity both available products consumption habits make it difficult assess consumer exposure psychoactive ingredients potentially harmful components. This work studies how relative ratios of two primary components extracts, Δ9-tetrahydrocannabinol (THC) terpenes, affect dosage these or (HPHCs). THC contains a monoterpene moiety has been previously shown emit similar...
Widespread legalization of cannabis throughout the United States has created a knowledge gap that leaves practitioners who manage voice disorders uninformed about this substance, commonly referred to as marijuana. The association inhalation and is rarely reported. However, studies on between respiration have been published; therefore, these may serve surrogate for phonation.To review literature cannabis-only consumption via smoking vaping with health function vocal mechanism aid clinical...
Heat-not-burn products, eg, I quit ordinary smoking (IQOS), are becoming popular alternative tobacco products. The nicotine aerosol protonation state has addiction implications due to differences in absorption kinetics and harshness. Nicotine free-base fraction (αfb) ranges from 0 1. Herein, we report αfb for IQOS aerosols by exchange-averaged 1H NMR chemical shifts of the methyl protons bulk verified headspace-solid phase microextraction-gas chromatography-mass spectrometry. ≈ products...
Abstract Flavoring chemicals utilized in electronic nicotine delivery systems (ENDS) have been shown to result an increase cellular inflammation, meanwhile, the effects of fruit and tobacco flavors on lung inflammation by nose-only exposures mice are relatively unknown. We hypothesized that C57BL/6J exposed flavored e-cigarettes would inflammation. were air, propylene glycol/vegetable glycerin (PG/VG), e-liquids “Apple”, “Cherry”, “Strawberry”, “Wintergreen”, “Smooth & Mild Tobacco”, for...
Pine rosin (colophony) has been identified as a new adulterant in cannabis oil for vaping. Its inhalation toxicity is significant health concern. For example, pine fumes are released during soldering, and have cited causative agent of occupational asthma. Symptoms also include desquamation bronchial epithelium, which observed EVALI patients. The sample analyzed herein contains medium chain triglycerides oleamide, the latter found synthetic marijuana product Spice, or K2. A combination NMR...
Pine rosin (colophony) has been identified as a new adulterant in cannabis oil for vaping. Its inhalation toxicity is significant health concern. For example, pine fumes are released during soldering, and have cited causative agent of occupational asthma. Symptoms also include desquamation bronchial epithelium, which observed EVALI patients. The sample analyzed herein contains medium chain triglycerides oleamide, the latter found synthetic marijuana product Spice, or K2. A combination NMR...