- Shoulder Injury and Treatment
- Lung Cancer Treatments and Mutations
- Shoulder and Clavicle Injuries
- Endodontics and Root Canal Treatments
- RNA modifications and cancer
- Foot and Ankle Surgery
- Dental Radiography and Imaging
- Cancer Immunotherapy and Biomarkers
- Trauma Management and Diagnosis
- Inflammatory Biomarkers in Disease Prognosis
- Lung Cancer Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Sexual function and dysfunction studies
- Cancer Genomics and Diagnostics
- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Tendon Structure and Treatment
- RNA Research and Splicing
- Cancer survivorship and care
- Kruppel-like factors research
- COVID-19 and healthcare impacts
- Facial Rejuvenation and Surgery Techniques
- Melanoma and MAPK Pathways
- Orthopedic Surgery and Rehabilitation
Southern University of Science and Technology
2023-2025
Jinan University
2023-2025
First Hospital of Jilin University
2017-2024
Jilin University
2017-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2024
Jiangxi Agricultural University
2023-2024
Qilu Hospital of Shandong University
2014-2023
Shenzhen University Health Science Center
2023
Beijing Hospital
2018-2022
Tianjin Children's Hospital
2022
Maxillary posterior teeth have close anatomical proximity to the maxillary sinus floor (MSF), and race, gender, age, side presence/absence of adjacent may influence mean distances between root apices MSF. This study aimed evaluate both relationship MSF, loss on distance roots MSF.Cone-beam computed tomography images were collected from 1011 Chinese patients. The MSF was divided into three types: Type OS (the apex extending below/outside MSF), CO contacting with IS above/inside MSF). minimum...
B7-H4, a member of B7 family, is transmembrane protein and inhibits T-cells immunity. However, in variety tumor cells, B7-H4 was detected predominantly intracellular compartments with unknown mechanism functions. In this study, we analyzed expression subcellular distribution by immunohistochemistry renal cell carcinoma (RCC) tissues. on the membrane, cytosol and/or nucleus The membrane nuclear significantly correlated stages RCC. Moreover, localization inversely intensity infiltrates...
The aim of the study was to investigate association between environmental factors and nonsyndromic cleft lip and/or palate (NSCL/P) in Yantai District, China. A retrospective case-control carried out. total 236 NSCL/P children were selected from Department Oral Maxillofacial Surgery Stomatological Hospital September 2013 December 2016 as cases; 209 controls chosen other diagnosis same department during period. 2 groups matched age sex. parents participants inquired regarding risk factors,...
ABSTRACT Esophageal squamous cell carcinoma ( ESCC ) is a globally prevalent malignancy known for its aggressive nature and unfavorable outcomes. Identifying new biomarkers crucial the early detection improved prognostication of . The circadian clock NIMA ‐related kinase 2 NEK2 are pivotal in cancer development. While impact rhythm disruptions on progression evident, specific contribution to these changes not well understood. Our study discovered as consistently differentially expressed gene...
To summarize the clinical and epidemiological characteristics of acute intussusception.This retrospective study included pediatric patients with intussusception admitted to Department Pediatric Surgery, Qilu Hospital (Qingdao), Cheeloo College Medicine, Shandong University, from January 2014 December 2019.A total 402 infants/children were (301 males 101 females) a mean age 2.4 ± 1.5 years (2 months 9 years). Thirty (7.5%) had history cold food intake, diarrhea, upper respiratory infection...
Mesoporous calcium-silicate nanoparticles (MCSNs) are advanced biomaterials for drug delivery and mineralization induction. They can load silver exhibit significantly antibacterial effects. However, the effects of MCSNs silver-loaded on dentin unknown. The (Ag) and/or zinc (Zn) incorporated (Ag-Zn-MCSNs) were prepared by a template method, their characterizations tested. Then filled into root canals investigated. Ag-Zn-MCSNs showed characteristics mesoporous materials sustained release ions...
To analyze the dynamic changes of chest CT images patients with corona virus disease-19 (COVID-19).Fifty-two cases COVID-19 were admitted in First Affiliated Hospital Zhejiang University School Medicine. The consecutive scans followed up for all an average 4 performed per patient during hospitalization. shortest interval between each scan was 2 days and longest 7 days. shape, number distribution lung shadows, as well characteristics lesions on reviewed.The obvious shadows infiltrating lungs...
Abstract Background and objective Tumor angiogenesis is vital for tumor growth. Recent evidence indicated that bone marrow-derived mesenchymal stem cells (BMSCs) can migrate to sites exert critical effects on growth through direct and/or indirect interactions with cells. However, the effect of BMSCs neovascularization has not been fully elucidated. This study aimed investigate whether fusion from glioma participated in angiogenesis. Methods SU3-RFP were injected into right caudate nucleus...
Abstract Background Better understanding of the danger zone anatomy in mesial roots (MRs) mandibular first molars (MFMs) may serve to decrease risk mishaps. This study aimed measure minimal distal dentine thicknesses MRs MFMs a native Chinese population using cone-beam computed tomography (CBCT). Methods CBCT images 1792 from 898 patients were analyzed. The mesiobuccal (MB) and mesiolingual (ML) canals below furcation 1, 2, 3, 4, 5 mm measured. association between root lengths, patient’s age...
To introduce a new postoperative pulmonary rehabilitation program named physical manipulation (PMPR) and to explore the effect of perioperative management, including PMPR, on patients with non-small cell lung cancer (NSCLC) after thoracoscopic lobectomy.A randomized controlled trial was conducted between April June 2021 at Department Thoracic Surgery, Beijing Hospital. Adult NSCLC who had undergone lobectomy were allocated treatment control groups using random number table. The group...
The aim of this study was to evaluate the clinical outcomes arthroscopy-assisted reconstruction coracoclavicular (CC) ligament using Endobutton for treating acromioclavicular (AC) joint dislocation.From March 2012 May 2013, a total 22 patients with fresh AC dislocation (Rockwood type III and V) were treated CC ligament. regular post-operation follow-up performed. Shoulder function assessed Constant-Murley scores. Postoperative efficacy surgery evaluated Karlsson criterion.The followed...
Esophageal cancer is a significant global health concern, ranking seventh in incidence and sixth mortality. It encompasses two pathological types: esophageal squamous cell carcinoma (ESCC) adenocarcinoma, with ESCC being more prevalent globally associated higher mortality rates. The POU (Pit-Oct-Unc) domain family transcription factors, comprising 15 members, play important roles embryonic development organ formation. Aberrant expression of POUs has been observed several human cancers,...
Background and Aims Needle injection needle-free were proven effective in improving glycated hemoglobin (HbA1c) type 2 diabetes mellitus (T2DM) patients. However, it is unclear if needle injections of insulin during intensive therapy hospitalized patients provide similar efficacy safety benefits. Methods A self-controlled cross-over study was conducted on 62 with T2DM who received long-acting short-acting or without needles. The 7-point blood glucose test performed the 6th day after...
This study aimed to investigate symptom subgroups and associated influencing factors in patients with advanced cancer.A cross-sectional was conducted, involving 416 cancer. The examined five symptoms: fatigue, pain, sleep impairment, anxiety, depression. Latent Profile Analysis (LPA) utilized classify subgroups. A multiple logistic regression analysis conducted explore the identified subgroups.The revealed three distinct among participants: "all low" (58.2%), characterized by normal symptoms...
Abstract Alternative splicing (AS), a crucial mechanism in post‐transcriptional regulation, has been implicated diverse cancer processes. Several variants of solute carrier (SLC) transporters reportedly play pivotal roles tumorigenesis and tumor development. However, an in‐depth analysis AS landscapes SLCs colon adenocarcinoma (COAD) is lacking. Herein, we analyzed data from The Cancer Genome Atlas identified 1215 events across 243 SLC genes, including 109 differentially expressed (DEAS)...
Aim: To clarify the regulatory roles of GLDCV1, first identified truncated glycine decarboxylase (GLDC), on cancer stem cells and tumorigenesis. Materials & methods: RT-PCR or RT-qPCR, immunoblotting immunohistochemical staining were applied to assess gene expression. MTT, BrdU incorporation colony formation assays used examine cell proliferation capacity. Soft agar in vivo transplantation evaluate cellular transformation Results conclusion: Expression GLDCV1 GLDC was enhanced non-small-cell...
The present study aimed to investigate the alteration of DNA damage signaling pathway profile in radiation-treated glioblastoma stem-like cells (GSLCs), and also explore potential targets for overcoming radioresistance. Serum-free medium was used isolate culture GSLCs. Cell growth detected using a cell counting kit-8 assay sorting analysis performed by flow cytometry. X-ray irradiation produced Siemens-Primus linear accelerator. Reverse transcription-quantitative polymerase chain reaction...
Background: Recently, calreticulin (CALR) gene mutations have been identified in patients with essential thrombocythemia (ET). A high-frequency of ET cases without Janus kinase 2 (JAK2) contain CALR and exhibit clinical characteristics different from those mutant JAK2. Thus, we investigated the frequency features Chinese Han ethnicity ET. Methods: We recruited 310 to analyze states CALR, JAK2V617F, MPLW515 by polymerase chain reaction direct sequencing. analyzed relationship between...