A5063538563- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Nail Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- Yeasts and Rust Fungi Studies
- Medical and Biological Ozone Research
- Selenium in Biological Systems
- Enterobacteriaceae and Cronobacter Research
- Infectious Diseases and Mycology
- Molecular Biology Techniques and Applications
- Antimicrobial Resistance in Staphylococcus
- Pneumocystis jirovecii pneumonia detection and treatment
- Sinusitis and nasal conditions
- Oral Health Pathology and Treatment
- Virus-based gene therapy research
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Pharmacological Effects of Natural Compounds
- Ginger and Zingiberaceae research
- Ocular Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Bacterial Identification and Susceptibility Testing
- Plant Pathogens and Resistance
- Garlic and Onion Studies
- Antibiotic Use and Resistance
Tehran University of Medical Sciences
2017-2023
Shiraz University of Medical Sciences
2021-2022
Shahed University
2011
Emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. Apparently, the novel (SARS-CoV-2) armed by special abilities to spread and dysregulate immune mechanisms. The likelihood oropharyngeal candidiasis (OPC) development in COVID-19 patients with list attributable risk factors for oral infections has not yet been investigated.We here aim investigate prevalence, causative agents antifungal susceptibility pattern OPC Iranian patients.A total 53 hospitalised were...
ABSTRACT The objective of this study was to assess the in vitro activity novel triazole antifungal drug, efinaconazole, and five comparators (luliconazole, lanoconazole, terbinafine, itraconazole, fluconazole) against a large collection Trichophyton interdigitale rubrum clinical isolates. geometric mean MICs were lowest for luliconazole (0.0005 μg/ml), followed by lanoconazole (0.002 efinaconazole (0.007 terbinafine (0.011 itraconazole (0.095 fluconazole (12.77 μg/ml). It appears that are...
Occurrence of non-Candida albicans Candida (NCAC) species that are associated with elevated MIC values and therapeutic failures increasing. As a result, timely accurate means identification to the level is becoming an essential part diagnostic practices in clinical settings. In this study, 301 clinically isolated yeast strains recovered from various anatomical sites [Blood (n = 145), other 156)] were used assess accuracy practicality API 20C AUX 21-plex PCR compared MALDI-TOF MS large...
Introduction. Given the limited number of candidaemia studies in Iran, profile yeast species causing bloodstream infections (BSIs), especially adults, remains limited. Although biochemical assays are widely used developing countries, they produce erroneous results, for rare species.Aim. We aimed to assess BSIs and compare accuracy Vitek 2 system 21-plex PCR.Methodology. Yeast blood isolates were retrospectively collected from patients recruited two tertiary care training hospitals Tehran...
Background and Purpose: Candida albicans is the most common species (sp.) isolated from fungal infections.Azole resistance in has been considerably increased last decades.Given toxicity of antimicrobial drugs, to antifungal agents, drug interactions, identification new agents seems essential.In this study, we assessed effects biogenic selenium nanoparticles on C. determined expression ERG11 CDR1 genes.Materials Methods: Selenium were synthesized with Bacillus sp.MSH-1.The ultrastructure was...
Background: Vulvovaginal candidiasis (VVC) is a common infection, affecting up to 75% of women at least once during their lifetime. In addition, approximately 5% patients may experience recurrent VVC. Candida albicans the most causative agent Overall, precise identification agents VVC necessary for effective treatment. Objectives: The purpose this study was identify molecular characteristics and antifungal susceptibility species, isolated from with in cities Shoush, Dezful, Andimeshk,...
Fungal rhinosinusitis (FRS) encompasses a various spectrum of diseases. Histopathology is the "reference method" for diagnosing FRS, but it cannot determine genus and species. Moreover, in more than 50% histopathologically proven cases, culture elicited no reliable results. This study was an attempt to evaluate diagnostic efficiency semi-nested polymerase chain reaction (PCR) from formalin-fixed paraffin-embedded (FFPE) functional endoscopic sinus surgery (FESS) FRS patients.One hundred ten...
Background and Purpose: Candidemia is a major cause of morbidity mortality among patients receiving immunosuppressive therapy those hospitalized with serious underlying diseases. Here, we investigated the epidemiological, clinical, mycological features candidemia in Tehran, Iran. Materials Methods: A prospective observational study all diagnosed was performed at two referral teaching hospitals Iran, from February to December 2018. Demographic characteristics, diseases, risk factors, clinical...
This case report describes the progressive wound infection in left thigh of a 34-year-old man due to an old landmine explosion. The developed into rapidly spreading skin and soft tissue necrotising Saksenaea infection, despite antifungal therapy surgical debridement. provides evidence that spp. should be added list mucoralean fungi can cause severe infection. It also highlights need for improved early diagnostic procedures enhanced understanding virulence factors contribute
Fungal species are responsible for 40%-50% of all microbial keratitis cases. Due to the low amount extracted DNA in ocular Formalin-fixed Paraffin-embedded (FFPE) samples, selecting a reliable molecular method is substantial issue this field.Sixty-six samples were collected via penetrating keratoplasty (PK) technique. Histopathology assays performed using hematoxylin-eosin (H&E) and periodic acid Schiff (PAS) staining methods. The ITS1/ITS4 ITS1/ITS2 primer pairs used semi-nested polymerase...
Hyperalgesia is considered as one of the marked signs subchronic diabetes mellitus that could affect life style patients. This study was designed to investigate antinociceptive effect chronic feeding Allium schoenoprasum L. (AS) leaf in streptozotocin-diabetic rats using formalin and hot tail immersion tests. Rats were divided into control, AS leaf-treated diabetic, sodium salicylate (SS)-treated diabetic groups. The treatment groups received oral administration leaf-mixed pelleted food (3%)...
Objectives: Candiduria is a common finding in the hospitalized patients.The goal of this study was to quantify interleukin (IL)-17 and IL-22 levels urine candiduric non-candiduric subjects.Odds ratios (OR) were adjusted for age, sex indwelling Foley. CI= confidence interval Conclusions:Our results indicated that direct examination, fungal culture, investigation IL-17 are useful tools diagnosis Candida urinary tract infection.
Background and Aims: Rhinosinusitis is an inflammation of the mucous membrane that may be caused by infectious agents such as bacteria, fungi viruses. Few studies have been carried out on role viruses in patients .The aim this study was molecular detection Adenoviruses sinus tissues nested polymerase chain reaction (PCR) Shiraz.Materials Methods: In present study, 103 paraffin-embedded biopsy specimens were subjected to DNA extraction tested for adenovirus using Nested PCR. The amplification...
Background and Objectives: There is a poor understanding about the prevalence characteristics of secondary bacterial fungal infections among Coronavirus diseases 2019 (COVID-19) superinfection in hospitalized patients. Materials Methods: Four hundred COVID-19-proven patients were enrolled this study. Nasal swabs for molecular assay (Real-time PCR) sputum samples further microbiological assays collected. Following broad-spectrum search, meta-analysis was performed using StatsDirect software...