A5023855544- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- Infectious Diseases and Mycology
- Plant Disease Resistance and Genetics
- Yeasts and Rust Fungi Studies
- Fungal Biology and Applications
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycotoxins in Agriculture and Food
- Metal Extraction and Bioleaching
- Bacterial Identification and Susceptibility Testing
- Plant-Microbe Interactions and Immunity
- Streptococcal Infections and Treatments
- Minerals Flotation and Separation Techniques
- Mycobacterium research and diagnosis
- Toxin Mechanisms and Immunotoxins
- Phytoplasmas and Hemiptera pathogens
- Skin Protection and Aging
- Antibiotic Use and Resistance
- Inflammation biomarkers and pathways
- Wound Healing and Treatments
- Extraction and Separation Processes
- Antimicrobial Peptides and Activities
- Inflammasome and immune disorders
Shanghai Changzheng Hospital
2016-2025
Second Military Medical University
2015-2025
Central South University
2021-2023
Intelligent Health (United Kingdom)
2022
Eastern Hepatobiliary Surgery Hospital
2021
Shanghai Medical College of Fudan University
2020
United Hospital
2019-2020
First Affiliated Hospital of Xinjiang Medical University
2016
Xinjiang Medical University
2016
Institute of Dermatology
2011-2013
Objectives: Development and validation of a single-step accurate reverse transcriptase loop-mediated isothermal amplification technique (RT-LAMP) for rapid identification SARS-COV-2 relative to commercial quantitative real-time PCR (qRT-PCR) assays allow prompt initiation proper medical care containment virus spread. Methods: Primers showing optimal in-silico features were subjected analytical sensitivity specificity assess the limit detection (LOD) cross-reaction with closely-...
Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and neoformans species complexes. After more than 15 years molecular genetic phenotypic studies much debate, proposal for taxonomic revision was made.
Clonal outbreaks of fluconazole-resistant (FLZR) Candida parapsilosis isolates have been reported in several countries. Despite its being the second leading cause candidemia, azole resistance mechanisms and clonal expansion FLZR C. blood not Turkey. In this study, we consecutively collected (n = 225) from fifth largest hospital Turkey (2007 to 2019), assessed their susceptibility pattern using CLSI M27-A3/S4, sequenced ERG11 for all MRR1, TAC1, UPC2 a selected number isolates. The typing...
As the second leading etiological agent of candidemia in Turkey and cause severe fluconazole-non-susceptible (FNS) clonal outbreaks, Candida parapsilosis emerged as a major health threat at Ege University Hospital (EUH). Evaluation microbiological pertinent clinical profiles patients due to C . EUH 2019–2020. isolates were collected from blood samples identified by sequencing internal transcribed spacer ribosomal DNA. Antifungal susceptibility testing was performed accordance with CLSI M60...
Cryptococcosis is an important fungal disease in Asia with estimated 140,000 new infections annually the majority of which occurs patients suffering from HIV/AIDS. Cryptococcus neoformans variety grubii (serotype A) major causative agent this disease. In present study, multilocus sequence typing (MLST) using ISHAM MLST consensus scheme for C. neoformans/C. gattii species complex was used to analyse nucleotide polymorphisms among 476 isolates pathogen obtained 8 Asian countries. Population...
Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococcosis in immunocompromised patients as well immunocompetent individuals. Host cell surface receptors recognize C. have been widely studied. However, intracellular sensing of this still poorly understood. Our previous studies demonstrated both biofilm and acapsular mutant are able to activate the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome. In current study, it was found...
Currently, research in sexual behavior and awareness female Chinese college students (FCCSs) is limited, particularly regarding the difference influencing factors between from rural areas urban areas. To fill gap available data, a cross-sectional study using anonymous questionnaires was conducted among 3193 six universities located Beijing, Shanghai, Guangzhou, China, February to June, 2013. Of 2669 respondents, 20.6% 20.9% of areas, respectively, reported being sexually experienced. The...
Cryptococcosis has been reported to be mostly associated with non-HIV-related patients in China. However, little is known about the molecular characteristics of clinical isolates from Cryptococcus neoformans species complex this country. In study, 115 were included. Molecular type VNI was most representative (n=103), followed by VGI (n=8), VNIII (n=2), VNIV (n=1), and VGII (n=1). With exception a serotype D mating isolate, all possessed MATalpha locus. Multilocus sequence typing (MLST)...
Identification of opportunistic yeasts in developing countries is mainly performed by phenotypic assays, which are time-consuming and prone to errors. Wrong species identification may result suboptimal treatment inaccurate epidemiological data. To improve rapidity accuracy identification, a diagnostic strategy using stepwise "YEAST PANEL multiplex PCR assays" targeting 21 clinically important yeast Candida, Trichosporon, Rhodotorula, Cryptococcus, Geotrichum was designed. Four hundred CBS...
Candida albicans, glabrata, and parapsilosis are three prevalent causes of candidiasis, worldwide. These species considered as nine medically important complex species. Limited knowledge about these newly recognized prompted us to develop a one-step, multiplex PCR detect identify them in clinical settings.Primers targeting Hyphal Wall Protein I gene for the C. dubliniensis, africana, Intergenic Spacer nivariensis, bracarensis, Intein ITS rDNA parapsilosis, orthopsilosis, metapsilosis were...
ABSTRACT Sebaceous gland diseases are a group of common dermatological with multiple causes. To date, systematic report the risk factors for sebaceous in adolescents has not been published. The aim this study was to assess prevalence and certain (seborrhea, seborrheic dermatitis, acne, androgenetic alopecia rosacea) their relationship gastrointestinal dysfunction adolescents. From August–October, 2002–2005, questionnaire survey carried out obtain epidemiological data about diseases. Using...
Background Cryptococcus neoformans is a pathogenic yeast that causes cryptococcosis, life threatening disease. The prevalence of cryptococcosis in Asia has been rising after the onset AIDS epidemic and estimates indicate more than 120 cases per 1,000 HIV-infected individuals year. Almost all cryptococcal disease both immunocompromised immunocompetent patients are caused by C. var. grubii. Epidemiological studies on pan-Asia have not reported. present work genetic diversity fungus...
The multidrug-resistant opportunistic yeast species of Candida auris, haemulonii, duobushaemulonii and pseudohaemulonii continue to endanger the healthcare settings around globe. Due lack a specific qPCR assay for detection these from clinical samples, we developed multiplex assay. Analytical specificity sensitivity showed 100% up ten genomes target with high value reproducibility (R2 >0.99). Subsequently, spiked serum our specifically could detect C. auris one genome >0.98). Lack cross...