Seong-Jae Lee

ORCID: 0000-0002-8060-4378
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About
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Research Areas
  • Peripheral Nerve Disorders
  • Orthopedic Surgery and Rehabilitation
  • Laser Applications in Dentistry and Medicine
  • Neurological Disease Mechanisms and Treatments
  • Elbow and Forearm Trauma Treatment
  • Medical Imaging and Analysis
  • Nerve Injury and Rehabilitation
  • Cervical and Thoracic Myelopathy
  • Shoulder Injury and Treatment
  • Healthcare and Venom Research
  • Muscle Physiology and Disorders
  • Neurological Disorders and Treatments
  • EEG and Brain-Computer Interfaces
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Infant Development and Preterm Care
  • Infrared Thermography in Medicine
  • Phagocytosis and Immune Regulation
  • Esophageal and GI Pathology
  • Caveolin-1 and cellular processes
  • Cancer Genomics and Diagnostics
  • Dysphagia Assessment and Management
  • AI in cancer detection
  • Neonatal and fetal brain pathology
  • Botulinum Toxin and Related Neurological Disorders
  • Corneal Surgery and Treatments

Seoul National University of Education
2021

Phosphatidylserine (PS) is an integral component of eukaryotic cell membranes and organelles. The Drosophila genome contains a single PS synthase (PSS)-encoding gene (Pss) homologous to mammalian PSSs. Flies with Pss loss-of-function alleles show reduced life span, increased bang sensitivity, locomotor defects, vacuolated brain, which are the signs associated neurodegeneration. We observed defective mitochondria in mutant adult as well elevated production reactive oxygen species, increase...

10.1016/j.isci.2021.102899 article EN cc-by-nc-nd iScience 2021-07-24
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