Alfred Janssen

ORCID: 0000-0002-8067-064X
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About
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Research Areas
  • Breast Implant and Reconstruction
  • Breast Cancer Treatment Studies
  • Reconstructive Surgery and Microvascular Techniques
  • Breast Lesions and Carcinomas
  • Cutaneous Melanoma Detection and Management
  • Radiomics and Machine Learning in Medical Imaging
  • Wound Healing and Treatments
  • Abdominal Trauma and Injuries
  • MRI in cancer diagnosis
  • Acute Ischemic Stroke Management
  • Phosphorus compounds and reactions
  • Organophosphorus compounds synthesis
  • Stroke Rehabilitation and Recovery
  • Congenital Diaphragmatic Hernia Studies
  • Cancer Genomics and Diagnostics
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Vascular Procedures and Complications
  • Abdominal vascular conditions and treatments
  • Surgical site infection prevention
  • Cancer Diagnosis and Treatment
  • Clinical practice guidelines implementation
  • Peripheral Artery Disease Management
  • Congenital Anomalies and Fetal Surgery
  • Antifungal resistance and susceptibility
  • Patient Satisfaction in Healthcare

Zuyderland Medisch Centrum
2017-2024

Damiaan Dicht bij het leven
2007-2014

Heinrich Heine University Düsseldorf
1987-2006

KU Leuven
1996

Factors influencing access to stroke unit (SU) care and data on quality of SU in Germany are scarce. We investigated characteristics patients directly admitted a as well patient-related structural factors adherence predefined indicators acute across hospitals providing care. Data were derived from the German Stroke Registers Study Group (ADSR), voluntary network 9 regional registers for monitoring Germany. Multivariable logistic regression analyses performed investigate direct admission SU....

10.1186/s12883-017-0819-0 article EN cc-by BMC Neurology 2017-03-09

Abstract Background To prevent recurrence after ileocolonic resection [ICR] in Crohn’s disease [CD], postoperative prophylaxis based on risk stratification is recommended international guidelines. This study aimed to evaluate CD implementation of a clinical management algorithm and determine the predictive value histological factors [RFs]. Methods In this multicentre, prospective cohort study, patients [≥16 years] scheduled for ICR were included. The advised no medication low-risk patients,...

10.1093/ecco-jcc/jjac128 article EN cc-by-nc Journal of Crohn s and Colitis 2022-09-11

Stroke patients should be cared for in accordance with evidence-based guidelines. The extent of implementation guidelines the acute care stroke Germany has been unclear to date.The regional quality assurance projects that cooperate framework German Registers Study Group (Arbeitsgemeinschaft Deutscher Schlaganfall-Register, ADSR) collected data on 627 hospitals 2012. hospital or transient ischemic attack (TIA) was assessed basis 15 standardized, indicators and compared across nine...

10.3238/arztebl.2014.0759 article EN Deutsches Ärzteblatt international 2014-11-07

Abstract Patients and breast cancer surgeons are frequently confronted with wound complications after mastectomy. Negative pressure therapy (NPWT) is a promising technique for preventing skin closure in elective surgery. However, clinical study evaluating postoperative following the use of NPWT, focusing solely on closed incisions patients undergoing mastectomy, has yet to be performed. Between June 2019 February 2020, 50 consecutive underwent mastectomy NPWT during first seven days. This...

10.1038/s41598-021-89036-3 article EN cc-by Scientific Reports 2021-05-05

Abstract Background Localisation techniques for nonpalpable breast cancer lesions and sentinel lymph node biopsy (SLNB) are associated with several drawbacks. A complete magnetic technique using seeds superparamagnetic iron oxide tracer could be an interesting alternative. This study describes a clear protocol the results of combined approach. Methods From August 2021 to February 2022 40 patients undergoing conserving surgery SLNB were eligible inclusion. was performed under ultrasound or...

10.1002/jso.27197 article EN Journal of Surgical Oncology 2023-01-04

Abstract Background Seroma formation is a common complication after breast cancer surgery and can lead to delayed wound healing, infection, patient discomfort repeated visits the outpatient clinic. Mastectomy combined with flap fixation becoming standard practice currently closed-suction drainage. There evidence showing that drainage may be insufficient in preventing seroma formation. reasonable doubt whether there still place for mastectomy when performed. We hypothesize closed suction does...

10.1186/s12885-020-07242-0 article EN cc-by BMC Cancer 2020-08-07

Background and Purpose: Quality indicators (QI) are an accepted tool to measure performance of hospitals in routine care. We investigated the association between quality acute stroke care defined by overall adherence evidence-based QI early outcome German hospitals. Methods: Patients with ischemic admitted one cooperating within ADSR (German Stroke Register Study Group) were analyzed. The is a voluntary network 9 regional registers monitoring across 736 Germany. was 11 processes correlation...

10.1161/strokeaha.120.029968 article EN Stroke 2020-10-12

Abstract Background Current pre-operative Sentinel Lymph Node (SLN) mapping using dual tracing is associated with drawbacks (radiation exposure, logistic challenges). Superparamagnetic iron oxide (SPIO) a non-inferior alternative for SLN in breast cancer patients. Limited research has been performed on SPIO use and MRI melanoma patients to identify SLNs. Methods Healthy participants underwent MRI-scanning pre- post SPIO-injection during 20 min. Workflow protocols varied dosage, massage...

10.1186/s12885-022-10146-w article EN cc-by BMC Cancer 2022-10-14

Abstract Purpose The outcome of the sentinel lymph node in breast cancer patients affects adjuvant treatment. Compared to conventional histopathology, analysis by one-step nucleic acid amplification (OSNA) harvests more micrometastasis, potentially inducing overtreatment. In this study we investigated impact OSNA on treatment, compared histopathological analysis. Methods Data from T1–3 with nodes analysed between January 2016 and December 2019 (OSNA group, n = 1086) Zuyderland Medical...

10.1007/s10549-023-07065-0 article EN cc-by Breast Cancer Research and Treatment 2023-07-27

(2007). Spontaneous Postpartum Subcapsular Liver Rupture. Acta Chirurgica Belgica: Vol. 107, No. 6, pp. 713-715.

10.1080/00015458.2007.11680156 article RO Acta Chirurgica Belgica 2007-01-01

Stenosis of the subclavian artery is uncommon and it rarely causes symptoms. Only symptomatic patients should be treated. We report a case chronic left upper limb ischemia caused by stenosis after repetitive clavicular fixation. The was first treated with carotid-subclavian bypass soon followed angioplasty stenting because occlusion bypass. Finally, failure these procedures necessitated subclavian-axillary crossover Both extra-anatomic percutaneous transluminal are safe effective. If...

10.1016/j.ijscr.2014.04.032 article EN International Journal of Surgery Case Reports 2014-01-01

Abstract Aminophosphine des Typs Rn P(NR′2)3-n (n= 2, 1, 0; R = Ph, c-Hex, (-)Men, t-Bu; R′= Me, Et, n-Bu) reagieren mit 4-Bis(aryl)-1, 3, 4-dithiadiphosphetan-2, 4-disulfiden (ArPS2)2(Ar: 4-Methoxyphenyl An, Naphthyl, Thienyl) unter formaler Insertion monomerer {ArPS2)-Einheiten in eine oder zwei der λ3-P—N-Bindung zu chiralen Organophosphorverbindungen Ar(R′2N)P(S)—S—PRn (NR′2)2-n(n 0) und [Ar(R′2N)P(S)—]2PR2(NR′2)1-n (n 1.0). In diesen werden bei Raumtemperatur bevorzugt die λ3—P—N—und...

10.1080/10426509008038044 article DE Phosphorus, sulfur, and silicon and the related elements 1990-07-01
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