A5009197958- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Pneumonia and Respiratory Infections
- Mycobacterium research and diagnosis
- Chronic Disease Management Strategies
- HIV-related health complications and treatments
- Diabetes and associated disorders
- Vitamin D Research Studies
- Hepatitis C virus research
- Blood Pressure and Hypertension Studies
- Clostridium difficile and Clostridium perfringens research
- Blood disorders and treatments
- Sodium Intake and Health
- Diabetes Treatment and Management
- Food Security and Health in Diverse Populations
- Global Public Health Policies and Epidemiology
- Microscopic Colitis
- Diabetes Management and Education
- HIV/AIDS Research and Interventions
- Cystic Fibrosis Research Advances
- Health and Medical Research Impacts
- Hormonal Regulation and Hypertension
- HIV, Drug Use, Sexual Risk
Emory University
2014-2025
University of South Carolina
2024
Georgia State University
2014-2022
National Center for Tuberculosis and Lung Disease
2015
David Tvildiani Medical University
2015
University of California, Irvine
2015
Takeda (Japan)
2015
Agnes Scott College
2014
Stanford Health Care
2014
Stanford University
2014
Background. In the United States, proportion of patients with extrapulmonary tuberculosis (EPTB) has increased relative to cases pulmonary tuberculosis. Patients central nervous system (CNS)/meningeal and disseminated EPTB those human immunodeficiency virus (HIV)/AIDS have mortality. The purpose our study was determine risk factors associated particular types EPTB.
Globally, 10 million incident cases of tuberculosis (TB) are reported annually, and 95% TB 80% tobacco users reside in low- middle-income countries. Smoking approximately doubles the risk disease mortality. We estimated proportion annual mortality attributable to smoking 32 high-TB-burden obtained country-specific estimates incidence, mortality, prevalence from World Health Organization Global Report (2017), surveillance reports (2015), Tobacco Atlas. Risk ratios for effect on incidence were...
National tuberculosis (TB) treatment facility in the country of Georgia.To determine prevalence diabetes mellitus (DM) and pre-DM among patients with TB using glycosylated-hemoglobin (HbA1c), to estimate association between DM clinical characteristics response anti-tuberculosis treatment.A cohort study was conducted from 2011 2014 at Centre for Lung Disease Tbilisi. Patients aged ⩾ 35 years pulmonary were included. HbA1c used define (⩾ 6.5%), 5.7-6.4%), no (<5.7%). Interviews medical chart...
Although diabetes mellitus (DM) is an established risk factor for active tuberculosis (TB) disease, little known about the association between pre-DM, DM, and latent tuberculous infection (LTBI).To estimate DM LTBI.We conducted a cross-sectional study among recently arrived refugees seen at health clinic in Atlanta, GA, USA, 2013 2014. Patients were screened using glycosylated-hemoglobin (HbA1c), LTBI QuantiFERON(®)-TB (QFT) test. HbA1c QFT results, demographic information, medical history...
Rates and risk factors for acquired drug resistance association with outcomes among patients multidrug-resistant tuberculosis (MDR TB) are not well defined. In an MDR TB cohort from the country of Georgia, susceptibility testing second-line drugs (SLDs) was performed at baseline every third month. Acquired defined as any SLD whose status changed susceptible to resistant follow-up. Among 141 patients, in Mycobacterium observed 19 (14%); prevalence 9.1% ofloxacin 9.8% capreomycin or kanamycin....
Objective To assess the effect of tobacco smoking on outcome tuberculosis treatment in Tbilisi, Georgia.Methods We conducted a prospective cohort study adults with laboratory-confirmed from May 2011 to November 2013.History was collected using standardized questionnaire adapted global adult survey.We considered therapy have poor if participants defaulted, failed or died.We used multivariable regressions estimate risk outcome.Findings Of 591 patients enrolled, 188 (31.8%) were past smokers...
Abstract Investments in digital health technologies such as artificial intelligence, wearable devices, and telemedicine may support Africa achieve United Nations (UN) Sustainable Development Goal for Health by 2030. We aimed to characterize map ecosystems of all 54 countries the context endemic infectious non-communicable diseases (ID NCD). performed a cross-national ecological analysis using 20-year data from World Bank, UN Economic Commission Africa, Organization, Joint Programme on...
BackgroundThe country of Georgia has a high prevalence tuberculosis (TB) and hepatitis C virus (HCV) infection. PurposeTo determine whether HCV co-infection increases the risk incident drug-induced among patients on first-line anti-TB drug therapy. MethodsProspective cohort study; serology was obtained all study subjects at time TB diagnosis; hepatic enzyme tests (serum alanine aminotransferase [ALT] activity) were baseline monthly during treatment. ResultsAmong 326 with culture-confirmed...
Diabetes is a risk factor for active tuberculosis (TB). Data are limited regarding the association between diabetes and TB drug resistance treatment outcomes. We examined characteristics of patients with without in Peruvian cohort at high drug-resistant TB. Among (TB-DM), we studied clinical/management outcomes.During 2005-2008, adults suspected respiratory symptoms Lima, Peru, who received rapid susceptibility testing (DST), were prospectively enrolled followed during treatment. Bivariate...
Abstract Background. Diabetes is a risk factor for active tuberculosis (TB), but little known about the relationship between diabetes and multidrug-resistant (MDR) TB. We aimed to assess factors primary MDR TB, including diabetes, determine whether reduced rate of sputum culture conversion among patients with Methods. From 2011 2014, we conducted cohort study at National Center Tuberculosis Lung Diseases in Tbilisi, Georgia. Adult (≥35 years) TB were eligible. Multidrug-resistant was defined...
OBJECTIVE In cross-sectional U.S. studies, patients with diabetes had twice the prevalence of latent tuberculosis infection (LTBI) compared those without diabetes. However, whether LTBI contributes to risk is unknown. We used longitudinal data determine if associated increased incidence. RESEARCH DESIGN AND METHODS conducted a retrospective cohort study among Veterans receiving care in Health Administration from 2000 2015. Eligibility included all preexisting who received tuberculin skin...
The impact of diabetes mellitus on tuberculosis (TB) treatment outcomes has not been well investigated in most sub-Saharan countries including Ethiopia. current study aimed to determine the association between and unsuccessful TB among drug-susceptible patients treated at selected health facilities Addis Ababa,
The association between student characteristics and depression among students attending women's colleges (single-sex institutions of higher education that exclude or limit males from admission) is poorly understood. Our objective was to estimate the prevalence determine behavioral social associated with a college.We administered cross-sectional Internet-based survey April May 2012 (n = 277) enrolled at private college in southeastern US. Center for Epidemiologic Studies Depression (CES-D)...
Diabetes mellitus (DM) is a risk factor for active tuberculosis (TB) but little known about the effect of DM on culture conversion among patients with multidrug-resistant (MDR)-TB. The primary aim was to estimate association between and rate TB sputum conversion. A secondary objective poor treatment outcomes MDR-TB. cohort all adult starting MDR-TB in country Georgia 2009-2011 followed during second-line therapy. Cox proportional models were used adjusted hazard Log-binomial regression...
There are limited data on the clinical impact of rapid diagnostic tests to detect multidrug-resistant tuberculosis (MDR-TB). We sought determine whether use a molecular test MDR-TB improves outcomes.A quasi-experimental study was conducted analyze Genotype MTBDRplus assay outcomes among patients with culture-confirmed pulmonary MDR-TB. Patients received treatment at National Center for Tuberculosis and Lung Diseases in Tbilisi, Georgia. Time initiation, culture conversion, infection control...
In the United States, multistate Salmonella outbreaks are most commonly linked to a food source; however, contact with live animals can also result in of human illness. To characterize animal and examine differences compared foodborne outbreaks, we analysed data reported Centers for Disease Control Prevention through National Outbreak Reporting System (NORS) from 2009 2014 primary mode transmission listed as "animal contact" or "food." Four hundred eighty-four were NORS; these 99 (20.5%)...