A5101630836- Cancer-related molecular mechanisms research
- Medical Imaging and Analysis
- Circular RNAs in diseases
- Spine and Intervertebral Disc Pathology
- RNA Research and Splicing
- Clinical practice guidelines implementation
- RNA modifications and cancer
Cixian People's Hospital
2020
Suzhou University of Science and Technology
2019
The aim of this study was to determine the function NEAT1/miR-23a-3p/SMC1A axis in cell proliferation and apoptosis acute myeloid leukemia (AML). Microarray analysis used screen differentially expressed lncRNAs/miRNAs/mRNAs primary AML cells. expression nuclear paraspeckle assembly transcript 1 (NEAT1), miR-23a-3p, structural maintenance chromosome alpha (SMC1A) cells THP-1 were measured by quantitative real-time polymerase chain reaction (qRT-PCR). A Cell Counting Kit-8 (CCK-8) assay...
Abstract Aim The aim of this study was to explore the role and molecular basis long noncoding RNA (lncRNA) TRHDE‐AS1 in lung cancer. Methods We used real‐time polymerase chain reaction analyze messenger expression levels TRHDE‐AS1, miR‐103, KLF4. cell viability, proliferation, invasion rates were assessed via 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide, Cell Counting Kit‐8, Transwell assays elucidate TRHDE‐AS1. Results Our results demonstrated that lncRNA is mainly located...