A5021521449- Heavy Metal Exposure and Toxicity
- Fluoride Effects and Removal
- Heavy metals in environment
- Mercury impact and mitigation studies
- Traditional Chinese Medicine Analysis
- Traditional Chinese Medicine Studies
- Allergic Rhinitis and Sensitization
- Gut microbiota and health
- Bone and Dental Protein Studies
- Cancer-related molecular mechanisms research
- Asthma and respiratory diseases
- Spectroscopy and Chemometric Analyses
- Viral Infectious Diseases and Gene Expression in Insects
- RNA modifications and cancer
- Anesthesia and Neurotoxicity Research
- Protein purification and stability
- Metabolomics and Mass Spectrometry Studies
- Child Nutrition and Water Access
- Retinoids in leukemia and cellular processes
- Mathematical Biology Tumor Growth
- Circular RNAs in diseases
- Water Treatment and Disinfection
- Protein Tyrosine Phosphatases
- Pharmaceutical and Antibiotic Environmental Impacts
- Enhanced Recovery After Surgery
Zhejiang University
2009-2025
Shanxi Agricultural University
2025
Jilin University
2019-2024
Jilin Province Science and Technology Department
2024
China Pharmaceutical University
2017-2024
Yangzhou University
2023
Jilin Agricultural University
2020
Second Affiliated Hospital of Luohe Medical College
2019
Abstract Aim The aim of this study was to explore the role and molecular basis long noncoding RNA (lncRNA) TRHDE‐AS1 in lung cancer. Methods We used real‐time polymerase chain reaction analyze messenger expression levels TRHDE‐AS1, miR‐103, KLF4. cell viability, proliferation, invasion rates were assessed via 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide, Cell Counting Kit‐8, Transwell assays elucidate TRHDE‐AS1. Results Our results demonstrated that lncRNA is mainly located...
Abstract The optimization of bioprocess for CHO cell culture involves careful consideration factors such as nutrient consumption, metabolic byproduct accumulation, growth, and monoclonal antibody (mAb) production. Valuable insights can be obtained by understanding cellular physiology to ensure robust efficient bioprocess. This study aims improve our the CHO‐K1 metabolism using 1 H NMR‐based metabolomics. Initially, variations in performance profiles under varied aeration conditions copper...
Vascular endothelial (VE)-cadherin junctional localization is known to play a central role in vascular development, barrier integrity, and homeostasis. The sarcoma homology domain containing protein tyrosine phosphatase (SHP)2 has been shown be involved regulating function; however, the mechanisms remain largely unknown. In this work SHP2 knockdown an HUVEC monolayer increased VE-cadherin internalization permeability. Loss of specifically augmented GTPase activity ADP-ribosylation factor...
Kelp, the brown alga distributed in coastal areas all over world, is also an important medicine food homology product China. However, levels and profiles of persistent organic pollutants (POPs) kelp have not been thoroughly investigated to date. Polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) emerging bromine flame retardants (eBFRs) were evaluated 41 samples from main producing The concentrations total PCBs, PBDEs eBFRs range 0.321–4.24 ng/g dry weight (dw),...
Abstract Introduction Herbal preparations are extensively utilised for the treatment of diseases in Asian countries. However, variations origin, climate, and production processes can lead to inconsistencies quality herbal preparations. Existing control methods only target a few components finished product but ignore pharmaceutical process. Therefore, this study intends develop comprehensive component analysis method intermediates process reveal change patterns substances deepen...
Throughout the coronavirus (COVID-19) pandemic, sanitizing products benzethonium chloride (BEC) and polyhexamethylene guanidine hydrochloride (PHMG-H) were widely used; however, few studies have investigated their combined toxicity to organisms. In present study, acute genotoxicity of BEC, PHMG-H, combination two as endpoints using Daphnia carinata model organism. For individual reagents, PHMG-H was found be more toxic than BEC in terms both mortality genotoxicity. DNA damage survival rate...
Choosing the right solvent and timely use is basis of rational drug most direct efficient way to improve safety traditional Chinese medicine injections. This study aimed evaluate influence preparation time on Shuanghuanglian injection inducing pseudo-allergic reactions with mouse mode. The two tests were carried out: (1) Comparative experiment between different solvent: appropriate concentration 0.9% sodium chloride 5% dextrose injection, mixed Evans blue, at one intravenous injected into...
Pancreatic cancer is one of the most malignant cancers with rapid progression and poor prognosis. The use transcriptional data can be effective in finding new biomarkers for pancreatic cancer. Many network-based methods used to identify are proposed, among which combination network controllability appears. However, existing do not study RNA, rely on priori mutations information, or only achieve classification tasks. In this study, we propose a method combined Relational Graph Convolutional...