We developed a facile strategy to synthesize series of water-soluble Pt, PtxNi1-x (0 < x 1), and Ni nanocrystals. The octahedral, truncated cubic shapes were uniformly controlled by varying crystal growth inhibition agents such as benzoic acid, aniline, carbon monoxide. compositions the nanocrystals effectively choice ratios between Pt precursors. In preliminary study probe their structure–activity dependence, we found that shapes, compositions, capping strongly influence catalyst...

Nanocatalytic therapy, involving the nanozyme-triggered production of reactive oxygen species (ROS) in tumor microenvironment (TME), has demonstrated potential but nanozymes still face challenges activity and specificity that compromise therapeutic efficacy. Herein, we report a strategy based on single-atom nanozyme to initiate cascade enzymatic reactions TME for tumor-specific treatment. The cobalt-single-atom nanozyme, with Co-N coordination N-doped porous carbon (Co-SAs@NC), displays...

To extend the functionalities of two-dimensional graphene-like layered compounds as versatile materials, modification transition metal dichalcogenide nanosheets such MoS2 with nanoparticles is great and widespread interest. However, few studies are available on preparation bimetallic supported MoS2. Herein, a facile efficient method to synthesize MoS2–PtAg nanohybrids by decorating ultrathin octahedral Pt74Ag26 alloy has been reported. The as-prepared MoS2–Pt74Ag26 were investigated novel...

We report the formation of single-crystalline octahedral Au-Ag nanoframes by a modified galvanic replacement reaction. Upon sequential addition AgNO(3), CuCl, and HAuCl(4) to octadecylamine solution, truncated polyhedral silver nanoparticles formed first then changed into nanoframes, without requiring conventional Ag removal step with additional oxidation etchant. The have 12 sides, all eight {111} faces are empty. side grows along [110] direction, diameter is less than 10 nm. selective gold...

Because of the requirements sustainable development as well desirability using molecular hydrogen a chemical reagent, it is paramount importance and great challenge to develop highly active selective catalysts for hydrogenation organic molecules, including substituted nitroarenes. We approach this question by probing unsupported bimetallic nanoparticles. A series novel RhxNiy (x, y = 1, 2, 3) nanoparticles were successfully prepared our "noble metal-induced reduction" strategy. Unsupported...

It is highly challenging but desirable to develop efficient catalysts for the activation of oxygen under mild conditions. Here, we report that various monodispersed metal nanoparticles (Ag, Pt, Co, Cu, Ni, Pd, and Au) efficiently activated molecular conditions, illustrated by aerobic oxidation anilines form either symmetric or asymmetric aromatic azo compounds. This discovery indicates exploiting catalytic power could enable sustainable chemistry suitable important reactions.

Single or few-layered MoS2 nanosheets, as a novel class of 2D nanomaterials, have received tremendous attention due to their fantastic physical and chemical properties. Here, we fabricated MoS2–PEG–CpG with small uniform size multifunctional platform for photothermal enhanced immunotherapy. nanosheets were by exfoliation further probe sonication. To realize MoS2-based adjuvant delivery, functionalized cytosine–phosphate–guanine (CpG) polyethylene glycol (PEG) form nanoconjugates. As an...

The complex pathogenic mechanisms of Alzheimer's disease (AD) include the aggregation β-amyloid peptides (Aβ) into oligomers or fibrils as well Aβ-mediated oxidative stress, which require comprehensive treatment. Therefore, inhibition Aβ and free-radical scavenging are essential for treatment AD. Nanoparticles (NPs) have been found to influence process in vitro. Herein, we report effects molybdenum disulfide (MoS2) NPs on aggregation. Polyvinylpyrrolidone-functionalized MoS2 were fabricated...

A novel magnetic-enhanced colorimetric assay was constructed based on aptamer conjugated PtCo bimetallic nanoparticles (NPs) with high oxidase-like catalytic activity, water solubility, low cell toxicity, and superparamagnetic properties. It found that the incorporation of magnetic metal Co atoms into NPs could not only be facilitated for separation, but also resulted in significantly improved activity cancer-cell detection without destructive H2O2. The present work demonstrates a general...

Here, we report facile fabrication of two-dimensional (2D) Pd nanosheet (NS)-supported zero-dimensional (0D) Au nanoparticles via galvanic replacement. In the synthesis, surface-clean NSs premade not only acted as a sacrifice template for replacing atoms by Au3+ ions, but served support substrate to nanoparticles. The morphology, structure, and composition products relied on Au/Pd feed atomic ratio. Interestingly, as-obtained 0D/2D AuxPd100–x (x = 4.5, 9.8, 21) nanocomposites showed...

Ag–Pd bimetallic nanocrystals (NCs) with tunable compositions and narrow size distributions were produced by a one-pot synthesis. The NC growth process was investigated time-dependent TEM, XRD, UV–vis studies. In the hydrodechlorination of 4-chlorophenol, AgPdx (x = 2, 4, 6, 9, 19) showed pronounced composition-dependent catalytic activities, leading to AgPd9 catalyst excellent activity.

Functional CuO/Pt nanocomposites were successfully constructed as peroxidase mimics for highly selective colorimetric detection of ascorbic acid.

Herein we have identified an optimal catalyst, Pd1Ag1.7, for the tandem reductive amination between nitroarenes and aldehydes (selectivity > 93%). Key to success is ability control compositions of investigational Pd1−xAgx (x = 0–1) catalysts, as well clear composition dependent activity/selectivity trend observed in this study. This catalyst features a wide substrate scope, excellent recyclability, activity selectivity under ambient conditions.

Quercetin nanoparticles fabricated by pulsed laser ablation showed enhanced bioavailability and multifunctional effects on amyloid-β mediated neurotoxicity.

Plasmon-enhanced electrocatalysis holds great promise for converting solar energy into chemical by efficiently harvesting photons electrocatalytic reactions. Here, we report a unique two-dimensional (2D) "Egg Waffle"-like heterostructure, i.e., gold nanoparticles intercalated in palladium nanosheet (AuNP-in-PdNS), effectively interfacing Au NPs with 2D Pd greatly enhancing activity under light illumination. A considerable enhancement, small overpotential of 19 mV (i.e., 4-fold decrease) at...

Nanowires have attracted much attention due to their potential bioapplications, such as delivery of drugs or sensing devices. Here we report the development a unique cell-capture and release platform based on nanowires. The combination nanowires, surface-binding peptides, cell-targeting aptamers leads specific efficient capture cancer cells. Moreover, binding processes are reversible, which is not only useful for downstream analysis but also reusability substrate. Our work provides new...