A5111133906- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Surface Chemistry and Catalysis
- Molecular Junctions and Nanostructures
- Supramolecular Self-Assembly in Materials
- Advanced biosensing and bioanalysis techniques
- Alzheimer's disease research and treatments
- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Crystallography and molecular interactions
- Surface and Thin Film Phenomena
- Nanocluster Synthesis and Applications
- Protein Structure and Dynamics
- Porphyrin and Phthalocyanine Chemistry
- Chemokine receptors and signaling
- Spectroscopy and Quantum Chemical Studies
- Force Microscopy Techniques and Applications
- Immunotherapy and Immune Responses
- Graphene research and applications
- Graphene and Nanomaterials Applications
- Electrochemical sensors and biosensors
- Computational Drug Discovery Methods
- Luminescence and Fluorescent Materials
Shanghai Institute of Organic Chemistry
2018-2025
Northwest A&F University
2025
University of Chinese Academy of Sciences
2016-2025
Fujian Medical University
2023-2025
Anhui Polytechnic University
2025
Chinese Academy of Sciences
2015-2024
National Center for Nanoscience and Technology
2015-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
Xiamen Medical College
2023-2024
Leiden University
2024
Abstract Physical hydrogels from existing polymers consisting of noncovalent interacting networks are highly desired due to their well‐controlled compositions and environmental friendliness; therefore, applied as adhesives, artificial tissues, soft machines. Nevertheless, these gels have suffered weak mechanical strength low water resistance. Current methodologies used fabricate mainly involve the freezing–thawing process (cryogels), which complicated in preparation short adjustment polymer...
Don't waste it! The treatment of Mg(OH)2 nanowaste containing CrVI with NaHCO3+Na2CO3 as mineralizer converts this into a nontoxic bulk material and concentrated solution the heavy metal in two-step process involving desorption rapid growth nanocrystals for complete separation from (see picture).
Understanding how molecules interact to form large-scale hierarchical structures on surfaces holds promise for building designer nanoscale constructs with defined chemical and physical properties. Here, we describe early advances in this field highlight upcoming opportunities challenges. Both direct intermolecular interactions those that are mediated by coordinated metal centers or substrates discussed. These can be additive, but they also interfere each other, leading new assemblies which...
Abstract Multidrug resistance (MDR) is a major impediment to cancer treatment. A promising strategy for treating MDR the joint delivery of combined anticancer agents tumor cells in single nanocarrier. Here, first time, Resveratrol (Res) was co-encapsulated with paclitaxel (PTX) PEGylated liposome construct carrier-delivered form combination therapy drug-resistant tumors. The composite had an average diameter 50 nm encapsulated efficiencies above 50%. studies demonstrated that could generate...
To extend the functionalities of two-dimensional graphene-like layered compounds as versatile materials, modification transition metal dichalcogenide nanosheets such MoS2 with nanoparticles is great and widespread interest. However, few studies are available on preparation bimetallic supported MoS2. Herein, a facile efficient method to synthesize MoS2–PtAg nanohybrids by decorating ultrathin octahedral Pt74Ag26 alloy has been reported. The as-prepared MoS2–Pt74Ag26 were investigated novel...
Abstract Infections caused by multidrug‐resistant (MDR) bacteria pose a threat to human health worldwide, making new effective antibacterial agents urgently desired. To date, it is still great challenge develop antibiotics for MDR with clear mechanisms. Herein, novel alternative copper clusters (CuCs) molecule precisely synthesized utilizing an artificially designed theanine peptide. The prepared CuCs exhibit excellent broad‐spectrum activity in vitro, including gram‐positive...
Multifunctional nanoplatforms for imaging-guided synergistic antitumor treatment are highly desirable in biomedical applications. However, anticancer is largely affected by the pre-existing hypoxic tumor microenvironment (TME), which not only causes resistance of tumors to photodynamic therapy (PDT), but also promotes tumorigenesis and progression. Here, a continuous O
We report on the synthesis of inorganic fullerene-like molybdenum disulfide (MoS2) nanoparticles by pulsed laser ablation (PLA) in water. The final products were characterized scanning electron microscopy, X-ray diffraction, transmission and resonance Raman spectroscopy, etc. Cell viability studies show that as-prepared MoS2 have good solubility biocompatibility, which may a great potential various biomedical applications. It is shown technique PLA water also provides green convenient method...
A multifunctional GO–IO–CS nanocomposite was synthesized. The can effectively capture and eliminate bacteria, largely destroy bacteria biofilms under NIR irradiation.
Single or few-layered MoS2 nanosheets, as a novel class of 2D nanomaterials, have received tremendous attention due to their fantastic physical and chemical properties. Here, we fabricated MoS2–PEG–CpG with small uniform size multifunctional platform for photothermal enhanced immunotherapy. nanosheets were by exfoliation further probe sonication. To realize MoS2-based adjuvant delivery, functionalized cytosine–phosphate–guanine (CpG) polyethylene glycol (PEG) form nanoconjugates. As an...
The complex pathogenic mechanisms of Alzheimer's disease (AD) include the aggregation β-amyloid peptides (Aβ) into oligomers or fibrils as well Aβ-mediated oxidative stress, which require comprehensive treatment. Therefore, inhibition Aβ and free-radical scavenging are essential for treatment AD. Nanoparticles (NPs) have been found to influence process in vitro. Herein, we report effects molybdenum disulfide (MoS2) NPs on aggregation. Polyvinylpyrrolidone-functionalized MoS2 were fabricated...
A novel magnetic-enhanced colorimetric assay was constructed based on aptamer conjugated PtCo bimetallic nanoparticles (NPs) with high oxidase-like catalytic activity, water solubility, low cell toxicity, and superparamagnetic properties. It found that the incorporation of magnetic metal Co atoms into NPs could not only be facilitated for separation, but also resulted in significantly improved activity cancer-cell detection without destructive H2O2. The present work demonstrates a general...
Here, we report facile fabrication of two-dimensional (2D) Pd nanosheet (NS)-supported zero-dimensional (0D) Au nanoparticles via galvanic replacement. In the synthesis, surface-clean NSs premade not only acted as a sacrifice template for replacing atoms by Au3+ ions, but served support substrate to nanoparticles. The morphology, structure, and composition products relied on Au/Pd feed atomic ratio. Interestingly, as-obtained 0D/2D AuxPd100–x (x = 4.5, 9.8, 21) nanocomposites showed...
N6 -methyladenosine (m6 A) modulators decide the fate of m6 A-modified transcripts and drive cancer development. RNA interference targeting A promise to be an emerging therapy but is challenging due its poor tumor high systematic toxicity. Here engineered small extracellular vesicles (sEVs) with CD47 expression cyclic arginine-glycine-aspartic (c(RGDyC)) modification are developed for effective delivery short interfering against reader YTH N6-methyladenosine binding protein 1 (YTHDF1) treat...