A5090156858- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Fatty Acid Research and Health
- Metabolism and Genetic Disorders
- Gestational Diabetes Research and Management
- Diet and metabolism studies
- Peroxisome Proliferator-Activated Receptors
- Diet, Metabolism, and Disease
- Pregnancy and preeclampsia studies
- Lipid metabolism and biosynthesis
- Lipid metabolism and disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Growth Hormone and Insulin-like Growth Factors
- Wildlife Ecology and Conservation
- Muscle metabolism and nutrition
- Metabolism, Diabetes, and Cancer
- Antioxidant Activity and Oxidative Stress
- Liver Disease Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Prenatal Substance Exposure Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Cholesterol and Lipid Metabolism
- Pancreatic function and diabetes
- Cancer, Lipids, and Metabolism
- Animal Behavior and Reproduction
Charles Darwin Foundation
2025
Benemérita Universidad Autónoma de Puebla
2024
Montclair State University
2024
Universidad San Pablo CEU
2014-2023
University of O'Higgins
2023
Simón Bolívar University
2007-2020
University of Matanzas
2020
Hospital Clínico Universitario Virgen de la Victoria
2008-2018
Universidad San Pablo
2000-2015
Universidad Juárez del Estado de Durango
2011-2015
To determine the contribution of maternal glucose and lipids to intrauterine metabolic environment fetal growth in pregnancies with gestational diabetes mellitus (GDM).In 150 pregnancies, serum triglycerides (TGs), cholesterol, free fatty acids (FFAs), glycerol, insulin, were determined cord blood during 3rd trimester. Maternal values came from oral tolerance testing profiles. Measurements abdominal circumference (AC) performed simultaneously sampling birth weight, BMI neonatal fat mass...
Insulin resistance plays a role in the pathogenesis of diabetes, including gestational diabetes. The glucose clamp is considered gold standard for determining vivo insulin sensitivity, both human and animal models. However, laborious, time consuming and, animals, requires anesthesia collection multiple blood samples. In studies, number simple indexes, derived from fasting levels, have been obtained validated against clamp. these indexes not rats their accuracy predicting altered sensitivity...
The effects of late pregnancy on metabolic fuels, liver composition, gluconeogenesis, and nitrogen metabolism have been examined in fed fasted rats.
To understand the mechanism responsible for maternal hyperlipidemia, 25 healthy pregnant women were studied longitudinally during three trimesters of gestation and at post-partum, 11 again post-lactation.Triglyceride cholesterol levels increased with in all lipoprotein fractions.However, greatest change appeared low density (LDL) high (HDL) lipoproteins, both which showed an increase their triglyceride/cholesterol ratio.The proportional distribution HDL subfractions that HDL2b fraction was...
Plasma lipoproteins were studied longitudinally at the 1st, 2nd, and 3rd trimester of gestation postpartum postlactation in 12 age-matched PGDM women, 9 GDM healthy control subjects. FPG HbA1c higher every case women than subjects, whereas patients, glucose was augmented only after parturition. FFA β-hydroxybutyrate levels both patients subjects during but not Total TGs VLDL, LDL, HDL increased with gestational time three groups declined postpartum, although total cholesterol followed a...
During late gestation, although maternal adipose tissue lipolytic activity becomes enhanced, products cross the placenta with difficulty. Under fasting conditions, free fatty acids (FFA) are used for ketogenesis by mother, and ketone bodies as fuels lipogenic substrates fetus. Maternal glycerol is preferentially glucose synthesis, saving other gluconeogenic substrates, like amino acids, fetal growth. Placental transfer of triglycerides null, but essential derived from diet, which transported...
The effects of late pregnancy on adipose tissue metabolism have been examined in fed and fasted rats. Lumbar fat was excised from 19-day pregnant age-matched virgin rats which had given unrestricted access to food (“fed”) or for 48 hr before sacrifice.
To evaluate the potential contribution of maternal glucose and lipids to fetal metabolic variables growth in pregnancies with normal tolerance comparison well-controlled gestational diabetes previously reported by us.In 190 oral tests (controls), insulin, lipid components were determined arterial cord blood serum. Birthweight neonatal fat mass obtained after delivery. Values adjusted for pre-pregnancy BMI, Caesarean section age. Measurements compared those reported.Maternal serum glucose,...
Whereas accumulation of fat depots occurs during the first two-thirds gestation, increased adipose tissue lipolysis and hyperlipidemia develops in last trimester. Insulin resistance estrogens late pregnancy contribute to these changes. Lipoprotein receptors fatty acid binding proteins placenta allow transfer long-chain polyunsaturated acids fetus. Enhanced oxidative stress may be related maternal hyperlipidemia. Maternal plasma nonesterified cholesterol correlate with those fetus,...
OBJECTIVE To determine the concentrations of adipocyte fatty acid–binding protein (AFABP) and other adipocytokines in maternal cord serum pregnant women with gestational diabetes mellitus (GDM) control subjects to relate them indexes insulin sensitivity. RESEARCH DESIGN AND METHODS In 86 98 GDM women, venous blood was collected before vaginal delivery arterial from immediately after delivery. Serum were measured by enzyme-linked immunosorbent assay (ELISA). RESULTS had higher prepregnancy...