A5055222317- Geriatric Care and Nursing Homes
- Nutrition and Health in Aging
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Dementia and Cognitive Impairment Research
- Frailty in Older Adults
- Liver Disease Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Drug-Induced Hepatotoxicity and Protection
- Intensive Care Unit Cognitive Disorders
- Healthcare Policy and Management
- Sleep and related disorders
- Folate and B Vitamins Research
- Retinal Imaging and Analysis
- Sleep and Wakefulness Research
- Sexual function and dysfunction studies
- Muscle Physiology and Disorders
- Chronic Kidney Disease and Diabetes
- Food Security and Health in Diverse Populations
- Retinal Diseases and Treatments
- Anesthesia and Sedative Agents
- Neurogenetic and Muscular Disorders Research
- Pregnancy and Medication Impact
- Pharmacological Effects and Toxicity Studies
- Pharmacology and Obesity Treatment
NYU Langone Health
2025
New York University
2024
Johns Hopkins University
2021-2022
Johns Hopkins Medicine
2021-2022
Hospital for Sick Children
2020
University of Toronto
2020
Cognitive impairment is common among persons with chronic kidney disease (CKD), due in part to reduced function. Given that physical activity (PA) known mitigate cognitive decline, we examined whether associations between CKD stage and global/domain-specific function differ by PA.We leveraged 3223 participants (≥60 years of age) enrolled National Health Nutrition Examination Survey (NHANES, 2011-2014), at least one measure objective [immediate recall (CERAD-WL), delayed (CERAD-DR), verbal...
ABSTRACT Background Short and long sleep durations are associated with cognitive dysfunction. Given the increased prevalence of abnormalities in chronic kidney disease (CKD) population, we tested whether association between duration function differed older adults without CKD. Methods This was a study 3215 (age ≥60 years) enrolled National Health Nutrition Examination Survey (2011–14) evaluating duration, (immediate recall, delayed verbal fluency, executive processing speed global cognition)...
Retinopathy and chronic kidney disease (CKD) are typically considered microvascular complications of diabetes, cardiovascular cerebrovascular diseases macrovascular complications; however, all may share common pathological mechanisms. This study quantified the association retinopathy with risk compared in persons diabetes.Retrospective cohort study.1,759 participants ARIC who had diabetes at visit 4 underwent retinal examination 3.Retinopathy.Prevalent CKD (estimated glomerular filtration...
ABSTRACT Background Medical distrust may hinder kidney transplantation (KT) access. Among KT candidates evaluated for waitlisting, we identified factors associated with high levels and quantified their association waitlisting. Methods 812 (2018–2023), assessed using the Revised Health Care System Distrust Scale across composite, competence, values subscales. We used linear regression to quantify associations between candidate neighborhood‐level scores. Cox models scores Results At...
Mutations in the nuclear matrix protein Matrin 3 ( MATR3 ) have been identified amyotrophic lateral sclerosis and myopathy. To investigate mechanisms underlying mutations neuromuscular diseases efficiently screen for modifiers of toxicity, we generated transgenic flies. Our findings indicate that expression wild‐type or mutant motor neurons reduces climbing ability lifespan flies, while their indirect flight muscles (IFM) results abnormal wing positioning muscle degeneration. In both IFM,...
Kidney transplant (KT) candidates often experience hospitalizations, increasing their delirium risk. Hospitalizations and are associated with worse post-KT outcomes, yet relationship pre-KT outcomes is less clear. Pre-KT may worsen access to KT due its negative impact on cognition ability maintain overall health.
Abstract Background Though older adults with chronic kidney disease (CKD) have a greater mortality risk than those without CKD, traditional factors poorly predict in this population. Therefore, we tested our hypothesis that two common geriatric factors, frailty and cognitive impairment, their co-occurrence, might improve prediction CKD. Methods Among participants aged ≥ 60 years from National Health Nutrition Examination Survey (2011–2014), quantified associations between (physical...
ABSTRACT Introduction Dietary restrictions for patients with end‐stage kidney disease (ESKD) are burdensome. Kidney transplantation (KT) candidates who lack neighborhood resources and burdened by dietary may have decreased access to KT. Methods In our two‐center prospective cohort study (2014–2023), 2471 ESKD were evaluated KT (candidates) reported their perceived burden of (not at all, somewhat/moderately, or extremely bothered). Neighborhood‐level socioeconomic factors derived from...
Background: Unintentional weight loss, a hallmark of frailty, predicts worse post-kidney transplantation (KT) outcomes. However, loss in candidates with obesity is often recommended to enhance transplant eligibility. We tested whether pre-evaluation change associated listing/waitlist mortality, considering intentionality and frailty. Methods: leveraged data on body mass index (BMI), intentionality, (one-year at evaluation), frailty (four-component Physical Frailty Phenotype evaluation) for...