Paul Müellner

ORCID: 0000-0002-8162-2455
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Research Areas
  • Photonic and Optical Devices
  • Advanced Fiber Optic Sensors
  • Optical Coherence Tomography Applications
  • Advanced Fiber Laser Technologies
  • Semiconductor Lasers and Optical Devices
  • Advanced Biosensing Techniques and Applications
  • Photonic Crystals and Applications
  • Advanced Fluorescence Microscopy Techniques
  • Advanced Photonic Communication Systems
  • Monoclonal and Polyclonal Antibodies Research
  • Retinal and Macular Surgery
  • Nanofabrication and Lithography Techniques
  • Molecular Junctions and Nanostructures
  • Plasmonic and Surface Plasmon Research
  • Advanced biosensing and bioanalysis techniques
  • Mechanical and Optical Resonators
  • Biosensors and Analytical Detection
  • Neural Networks and Reservoir Computing
  • 3D Printing in Biomedical Research
  • Microfluidic and Bio-sensing Technologies
  • Optical Network Technologies
  • Analytical Chemistry and Sensors
  • Retinal Diseases and Treatments
  • Microfluidic and Capillary Electrophoresis Applications
  • Characterization and Applications of Magnetic Nanoparticles

Austrian Institute of Technology
2014-2024

Abstract In this work, we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on photonic integrated chip. The diffraction gratings used spectral-domain can be replaced by circuits comprising an arrayed waveguide grating. Two grating designs with 256 channels were tested, which enabled the first chip-based three-dimensional human retinal measurements. Design 1 supports bandwidth of 22 nm, sensitivity up to 91 dB (830 µW ) axial resolution 10.7 µm...

10.1038/s41377-020-00450-0 article EN cc-by Light Science & Applications 2021-01-05

In this numerical study, we show that by exploiting the advantages of horizontal silicon slot wave-guide structure nonlinear interaction can be significantly increased compared to vertical waveguides. The deposition a 20 nm thin optically layer with low refractive index sandwiched between two wires 220 width and 205 height could enable nonlinearity coefficient gamma more than 2 x 10(7) W(-1)km(-1).

10.1364/oe.17.009282 article EN cc-by Optics Express 2009-05-19

We present a CMOS-compatible silicon nitride (Si3N4) waveguide technology platform suitable for monolithic co-integration with optoelectronics in the visible and <1.1 μm near infrared wavelength region. With an optimized fabrication process employing low-temperature plasma enhanced chemical vapour deposition (PECVD) reactive ion etching (RIE), propagation losses of 0.86 dB/cm were achieved at λ=850 nm wire waveguides cross section 600x250 nm2. As example application we show Mach-Zehnder...

10.1016/j.proeng.2015.08.728 article EN Procedia Engineering 2015-01-01

A complementary cell analysis method has been developed to assess the dynamic interactions of tumor cells with resident tissue and immune using optical light scattering impedance sensing shed on behavior. The combination electroanalytical biosensing technologies integrated in a lab-on-a-chip allows for continuous, label-free, noninvasive probing cell-to-cell between adherent nonadherent cocultures, thus providing real-time insights into responses under physiologically relevant conditions....

10.1021/ac4033406 article EN Analytical Chemistry 2013-11-12

The fabrication of flexible low-loss, thin-film, foil-based polymer waveguides with grating couplers employing a high-volume industrial roll-to-roll process is demonstrated. embossed feature propagation losses less than 1 dB/cm (633 nm, TE polarization), bending 0.4-0.8 dB/360° for radii as small 2 mm, and coupling efficiencies up to 25%. In addition, the possess thermo-optic coefficient -1.58×10(-4) 1/°C. fabricated are promising candidates short-distance data communication well sensing...

10.1364/ao.52.004510 article EN Applied Optics 2013-06-21

We report a new method for detecting human IgG (hIgG) in serum on integrated-optical Mach-Zehnder interferometer biosensors realized high index contrast polymer material system. In the linear range of sensor (5–200 nM) we observed excellent signal recoveries (95–110%) buffer and samples, which indicate absence matrix effects. Signal enhancement was reached by using secondary anti-human antibodies, bind to immobilized target IgGs allow concentrations down 100 pM. This based optical is fully...

10.1002/jbio.201500280 article EN Journal of Biophotonics 2015-12-10

Biotin- and iminobiotin-bonded surfaces obtained by thiol–ene chemistry subsequent modification with polyamines were characterized respect to streptavidin-binding capacity reversibility for photonic biosensing using X-ray photoelectron spectroscopy Mach–Zehnder-interferometric sensors. The streptavidin–iminobiotin system was exploited reversible multilayer deposition determination of affinity constants on each layer.

10.1039/c3cc48640k article EN cc-by Chemical Communications 2014-01-01

Silicon nitride based photonic integrated circuits offer a wavelength operation window in the near infrared down to visible light, which makes them attractive for life science applications.However, they exhibit significantly different behavior comparison better established silicon on insulator counterparts due lower index contrast.One of most important building blocks are broadband couplers with defined coupling ratio.We present asymmetric directional coupler designs 50/50 and 90/10...

10.1364/osac.1.001324 article EN cc-by OSA Continuum 2018-12-11

In this paper, we present a novel concept for multi-channel swept source optical coherence tomography (OCT) system based on photonic integrated circuits (PICs). At the core of is low-loss polarization dependent path routing approach allowing lower excess loss compared to previously shown PIC-based OCT systems, facilitating parallelization measurement units. As proof routing, silicon nitride single-channel operating at 840 nm was implemented and used acquire in-vivo tomograms human retina....

10.1364/oe.404588 article EN cc-by Optics Express 2020-10-05

Abstract Photonic integrated circuits (PICs) represent a promising technology for the much-needed medical devices of today. Their primary advantage lies in their ability to integrate multiple functions onto single chip, thereby reducing complexity, size, maintenance requirements, and costs. When applied optical coherence tomography (OCT), leading tool state-of-the-art ophthalmic diagnosis, PICs have potential increase accessibility, especially scenarios, where weight, or costs are limiting...

10.1186/s43074-024-00150-7 article EN cc-by PhotoniX 2024-10-11

As a leading provider of sensing solutions ams AG is developing semiconductor sensors in wide variety fields. One the key competences lies optical sensing. To widen company's portfolio this field we have been processes for fully integrated CMOS compatible photonic components based on Si3N4 last few years. This contribution will give an overview process as post-processing flow standard CMOS, some basic building blocks and their properties, example use medical applications.

10.3390/proceedings2131023 article EN cc-by 2018-11-19

We report the simulation, design and experimental validation of various PECVD silicon nitride photonic building blocks required for implementation a CMOS-compatible integrated circuit technology platform operating in 850 nm 600 wavelength domain. In particular, we discuss an inverted taper structure efficient coupling light to from chip, propagation bend losses as well broadband power polarization beam splitters region. region, demonstrate realization optically pumped dye-doped polymer laser...

10.1117/12.2509982 article EN 2019-03-04

We present the technological verification of a size-optimized 160-channel, 50-GHz silicon nitride-based AWG-spectrometer. The spectrometer was designed for TM-polarized light with central wavelength 850 nm applying our proprietary "AWG-Parameters" tool. For simulations AWG layout, WDM PHASAR photonics tool from Optiwave used. simulated results show satisfying optical properties However, high-channel count causes large size standard design approaches. To solve this problem we special taper...

10.1007/s00340-019-7192-1 article EN cc-by Applied Physics B 2019-05-04

In order to enable local functionalisation of label-free optical waveguide biosensors in a cost effective mass-fabrication compatible manner, we investigate surface modification employing inkjet printing a) functional polymers (biotin-modified polyethyleneimine (PEI-B)) implement high receptor densities at the and b) UV-curable benzophenone dextran (benzo-dextran) form voluminous porous hydrogel matrix. The combination these approaches on single chip is promising for detection biomolecules....

10.1016/j.proeng.2016.11.113 article EN Procedia Engineering 2016-01-01

Broadband low loss and ultra-low crosstalk waveguide crossings are a crucial component for photonic integrated circuits to allow higher integration density of functional components an increased flexibility in the layout. We report design optimized silicon nitride based on multimode interferometer structures intersecting light paths TE/TE-like, TM/TM-like, TE/TM-like polarized near infrared wavelength region 790 nm 890 nm. The crossing diverse polarization modes facilitates dual operation...

10.1364/osac.381003 article EN cc-by OSA Continuum 2020-01-27

We introduce a novel biosensor concept, which employs hybrid nanoparticles consisting of magnetic nanorods encapsulated by noble metal shells. These have the potential to directly signal presence analyte molecules in sample solution via inducing change their rotational dynamics on binding, thus circumventing need extensive preparation. While nanoparticles' cores enable rotation an external field, shells are used monitor through excitation and observation longitudinal plasmon resonances....

10.1016/j.proeng.2010.09.304 article EN Procedia Engineering 2010-01-01

We theoretically investigate the lateral leakage in fully symmetric horizontal rib-type slot waveguides caused by coupling between TM-like mode and a TE slab mode. The mechanism is described dependence on geometry parameters studied using variational mode-matching method. In addition, effective-index method to solve transcendent eigenmode equation of applied compared with aforementioned rigorous numerical show that this semi-analytical approach yields results sufficiently high accuracy. For...

10.1364/oe.16.000287 article EN cc-by Optics Express 2008-01-01

Abstract Photonic integrated circuits (PIC) provide promising functionalities to significantly reduce the size and costs of optical coherence tomography (OCT) systems. This paper presents an imaging platform operating at a center wavelength 830 nm for ophthalmic application using PIC-based swept source OCT. An on-chip Mach–Zehnder interferometer (MZI) configuration, which comprises input power splitter, polarization beam splitters in sample reference arm, 50/50 coupler signal interference...

10.1038/s41598-021-00637-4 article EN cc-by Scientific Reports 2021-10-26

The impressive progress of silicon photonic integrated device technology during the past fifteen years has been primarily driven by requirements optical data- and telecommunication. Research development in photonics therefore focused on telecom wavelengths 1.55 µm 1.31 regions silicon-on-insulator (SOI) material as waveguide integration platform. rising cost burden traditional healthcare system well increasing health consciousness among people is stimulating decentralization creating a...

10.1109/piers.2016.7734463 article EN 2016-08-01

We report several PECVD silicon nitride photonic building blocks required for the implementation of a CMOS-compatible integrated circuit technology platform operating in 850 nm and 600 wavelength domain. In particular, region we discuss low-loss broadband 1x2 power splitter loop mirror. region, present new results on an optically pumped dye-doped polymer laser that couples its light directly into waveguide. Moreover, design considerations waveguide based gas sensing concept detecting target...

10.1117/12.2524277 article EN 2019-04-26
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